Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site

Summary for 1S26

Related1K90 1LVC
DescriptorCalmodulin-sensitive adenylate cyclase, Calmodulin, YTTERBIUM (III) ION, ... (5 entities in total)
Functional Keywordsampcpp, edema factor, calmodulin, toxin, lyase-metal binding protein complex, lyase/metal binding protein
Biological sourceBacillus anthracis
Total number of polymer chains6
Total molecular weight228871.08
Shen, Y.,Zhukovskaya, N.L.,Bohm, A.,Tang, W.-J. (deposition date: 2004-01-08, release date: 2004-04-13, Last modification date: 2019-11-20)
Primary citation
Shen, Y.,Guo, Q.,Zhukovskaya, N.L.,Drum, C.L.,Bohm, A.,Tang, W.-J.
Structure of anthrax edema factor-calmodulin-adenosine-5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site
Biochem.Biophys.Res.Commun., 317:309-314, 2004
PubMed: 15063758 (PDB entries with the same primary citation)
DOI: 10.1016/j.bbrc.2004.03.046
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.28633 3.3% 7.1% 5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-14