1LVC

Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 2' deoxy, 3' anthraniloyl ATP

Summary for 1LVC

Related1K90
Descriptorcalmodulin-sensitive adenylate cyclase, calmodulin, YTTERBIUM (III) ION, ... (5 entities in total)
Functional Keywordshelical domain, protein-protein complex, lyase
Biological sourceBacillus anthracis
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Cellular locationSecreted P40136
Cytoplasm, cytoskeleton, spindle P02593
Total number of polymer chains6
Total molecular weight228969.64
Authors
Shen, Y.,Lee, Y.-S.,Soelaiman, S.,Bergson, P.,Lu, D.,Chen, A.,Beckingham, K.,Grabarek, Z.,Mrksich, M.,Tang, W.-J. (deposition date: 2002-05-28, release date: 2002-12-04, Last modification date: 2011-07-13)
Primary citation
Shen, Y.,Lee, Y.-S.,Soelaiman, S.,Bergson, P.,Lu, D.,Chen, A.,Beckingham, K.,Grabarek, Z.,Mrksich, M.,Tang, W.-J.
Physiological calcium concentrations regulate calmodulin binding and catalysis of adenylyl cyclase exotoxins
Embo J., 21:6721-6732, 2002
PubMed: 12485993 (PDB entries with the same primary citation)
DOI: 10.1093/emboj/cdf681
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.6 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.306525.6%10.4%2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution