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1K93

Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin

Summary for 1K93
Entry DOI10.2210/pdb1k93/pdb
Related1K8T 1K9O
DescriptorCALMODULIN-SENSITIVE ADENYLATE CYCLASE, CALMODULIN, SULFATE ION, ... (4 entities in total)
Functional Keywordsedema factor, calmodulin, adenylyl cyclase, anthrax, toxin, lyase-metal binding protein complex, lyase/metal binding protein
Biological sourceBacillus anthracis
More
Cellular locationSecreted: P40136
Cytoplasm, cytoskeleton, spindle: P02593
Total number of polymer chains6
Total formula weight225746.09
Authors
Drum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J. (deposition date: 2001-10-26, release date: 2002-01-23, Last modification date: 2024-02-07)
Primary citationDrum, C.L.,Yan, S.-Z.,Bard, J.,Shen, Y.-Q.,Lu, D.,Soelaiman, S.,Grabarek, Z.,Bohm, A.,Tang, W.-J.
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.
Nature, 415:396-402, 2002
Cited by
PubMed: 11807546
DOI: 10.1038/415396a
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.95 Å)
Structure validation

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