Author results

1BIS
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HIV-1 INTEGRASE CORE DOMAIN
Descriptor:HIV-1 INTEGRASE
Authors:Goldgur, Y., Dyda, F., Hickman, A.B., Jenkins, T.M., Craigie, R., Davies, D.R.
Deposit date:1998-06-19
Release date:1998-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BIU
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HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++
Descriptor:HIV-1 INTEGRASE, MAGNESIUM ION
Authors:Goldgur, Y., Dyda, F., Hickman, A.B., Jenkins, T.M., Craigie, R., Davies, D.R.
Deposit date:1998-06-19
Release date:1998-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BIZ
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HIV-1 INTEGRASE CORE DOMAIN
Descriptor:HIV-1 INTEGRASE, CACODYLATE ION
Authors:Goldgur, Y., Dyda, F., Hickman, A.B., Jenkins, T.M., Craigie, R., Davies, D.R.
Deposit date:1998-06-21
Release date:1998-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.
Proc.Natl.Acad.Sci.USA, 95, 1998
1EIY
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THE CRYSTAL STRUCTURE OF PHENYLALANYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH COGNATE TRNAPHE
Descriptor:TRNA(PHE), PHENYLALANYL-TRNA SYNTHETASE
Authors:Goldgur, Y., Mosyak, L., Reshetnikova, L., Ankilova, V., Safro, M.
Deposit date:2000-02-29
Release date:2000-03-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:The crystal structure of phenylalanyl-tRNA synthetase from thermus thermophilus complexed with cognate tRNAPhe.
Structure, 5, 1997
1QS4
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CORE DOMAIN OF HIV-1 INTEGRASE COMPLEXED WITH MG++ AND 1-(5-CHLOROINDOL-3-YL)-3-HYDROXY-3-(2H-TETRAZOL-5-YL)-PROPENONE
Descriptor:PROTEIN (HIV-1 INTEGRASE (E.C.2.7.7.49)), MAGNESIUM ION, 1-(5-CHLOROINDOL-3-YL)-3-HYDROXY-3-(2H-TETRAZOL-5-YL)-PROPENONE
Authors:Goldgur, Y., Craigie, R., Fujiwara, T., Yoshinaga, T., Davies, D.R.
Deposit date:1999-06-25
Release date:1999-11-17
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design.
Proc.Natl.Acad.Sci.USA, 96, 1999
3ETP
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THE CRYSTAL STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE EPHB2 RECEPTOR AT 2.0 A RESOLUTION
Descriptor:Ephrin type-B receptor 2
Authors:Goldgur, Y., Paavilainen, S., Nikolov, D.B., Himanen, J.P.
Deposit date:2008-10-08
Release date:2008-10-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution.
Acta Crystallogr.,Sect.F, 65, 2009
2OQX
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CRYSTAL STRUCTURE OF THE APO FORM OF E. COLI TRYPTOPHANASE AT 1.9 A RESOLUTION
Descriptor:Tryptophanase, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Goldgur, Y., Kogan, A., Gdalevsky, G., Parola, A., Cohen-Luria, R., Almog, O.
Deposit date:2007-02-01
Release date:2007-02-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structure of apo tryptophanase from Escherichia coli reveals a wide-open conformation.
Acta Crystallogr.,Sect.D, 63, 2007
4W1Y
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI TRYPTOPHANASE IN 'SEMI-HOLO' FORM
Descriptor:Tryptophanase, SULFATE ION
Authors:Goldgur, Y.
Deposit date:2014-08-13
Release date:2014-12-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of Escherichia coli tryptophanase in holo and `semi-holo' forms.
Acta Crystallogr.,Sect.F, 71, 2015
4W4H
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ESCHERICHIA COLI TRYPTOPHANASE IN HOLO FORM
Descriptor:Tryptophanase
Authors:Goldgur, Y.
Deposit date:2014-08-14
Release date:2014-12-17
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structures of Escherichia coli tryptophanase in holo and `semi-holo' forms.
Acta Crystallogr.,Sect.F, 71, 2015
5TT5
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ESCHERICHIA COLI LIGA (K115M) IN COMPLEX WITH NAD+
Descriptor:DNA ligase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION, ...
Authors:Goldgur, Y., Unciuleac, M.-C., Shuman, S.H.
Deposit date:2016-11-01
Release date:2017-03-08
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.552 Å)
Cite:Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5TT6
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T4 RNA LIGASE 1 (K99M)
Descriptor:T4 RNA ligase 1, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Goldgur, Y., Unciuleac, M.-C., Shuman, S.H.
Deposit date:2016-11-01
Release date:2017-03-08
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.187 Å)
Cite:Two-metal versus one-metal mechanisms of lysine adenylylation by ATP-dependent and NAD(+)-dependent polynucleotide ligases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6NVO
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CRYSTAL STRUCTURE OF PSEUDOMONAS PUTIDA NUCLEASE MPE
Descriptor:Nuclease MPE, MANGANESE (II) ION
Authors:Goldgur, Y., Shuman, S., Ejaz, A.
Deposit date:2019-02-05
Release date:2019-03-27
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Activity and structure of Pseudomonas putida MPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster.
J. Biol. Chem., 2019
6NVP
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CRYSTAL STRUCTURE OF PSEUDOMONAS PUTIDA NUCLEASE MPE
Descriptor:Nuclease MPE, MANGANESE (II) ION
Authors:Goldgur, Y., Shuman, S., Ejaz, A.
Deposit date:2019-02-05
Release date:2019-03-27
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Activity and structure of Pseudomonas putida MPE, a manganese-dependent single-strand DNA endonuclease encoded in a nucleic acid repair gene cluster.
J. Biol. Chem., 2019
3G5K
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STRUCTURE AND ACTIVITY OF HUMAN MITOCHONDRIAL PEPTIDE DEFORMYLASE, A NOVEL CANCER TARGET
Descriptor:Peptide deformylase, mitochondrial, ACTINONIN, ...
Authors:Escobar-Alvarez, S., Goldgur, Y., Yang, G., Ouerfelli, O., Li, Y., Scheinberg, D.A.
Deposit date:2009-02-05
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and activity of human mitochondrial peptide deformylase, a novel cancer target
J.Mol.Biol., 387, 2009
3G5P
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STRUCTURE AND ACTIVITY OF HUMAN MITOCHONDRIAL PEPTIDE DEFORMYLASE, A NOVEL CANCER TARGET
Descriptor:Peptide deformylase, mitochondrial, COBALT (II) ION, ...
Authors:Escobar-Alvarez, S., Goldgur, Y., Yang, G., Ouerfelli, O., Li, Y., Scheinberg, D.A.
Deposit date:2009-02-05
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and activity of human mitochondrial peptide deformylase, a novel cancer target
J.Mol.Biol., 387, 2009
4M4P
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CRYSTAL STRUCTURE OF EPHA4 ECTODOMAIN
Descriptor:Ephrin type-A receptor 4, N-ACETYL-D-GLUCOSAMINE
Authors:Xu, K., Tsvetkova-Robev, D., Xu, Y., Goldgur, Y., Chan, Y.-P., Himanen, J.P., Nikolov, D.B.
Deposit date:2013-08-07
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.081 Å)
Cite:Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
4M4R
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EPHA4 ECTODOMAIN COMPLEX WITH EPHRIN A5
Descriptor:Ephrin type-A receptor 4, Ephrin-A5, N-ACETYL-D-GLUCOSAMINE
Authors:Xu, K., Tsvetkova-Robev, D., Xu, Y., Goldgur, Y., Chan, Y.-P., Himanen, J.P., Nikolov, D.B.
Deposit date:2013-08-07
Release date:2013-10-30
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
1PYS
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PHENYLALANYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS
Descriptor:PHENYLALANYL-TRNA SYNTHETASE, MAGNESIUM ION
Authors:Safro, M., Mosyak, L., Goldgur, Y., Reshetnikova, L., Delarue, M.
Deposit date:1996-11-14
Release date:1997-11-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of phenylalanyl-tRNA synthetase from Thermus thermophilus.
Nat.Struct.Biol., 2, 1995
2V0Y
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CRYSTAL STRUCTURE OF APO C298S TRYPTOPHANASE FROM E.COLI
Descriptor:TRYPTOPHANASE, CHLORIDE ION, MAGNESIUM ION
Authors:Kogan, A., Gdalevsky, G.Y., Cohen-Luria, R., Goldgur, Y., Parola, A.H., Almog, O.
Deposit date:2007-05-21
Release date:2008-06-10
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational Changes and Loose Packing Promote E. Coli Tryptophanase Cold Lability.
Bmc Struct.Biol., 9, 2009
2V1P
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CRYSTAL STRUCTURE OF THE APO FORM OF Y74F MUTANT E. COLI TRYPTOPHANASE
Descriptor:TRYPTHOPANASE, CHLORIDE ION, MAGNESIUM ION
Authors:Kogan, A., Gdalevsky, G.Y., Cohen-Luria, R., Goldgur, Y., Parola, A.H., Almog, O.
Deposit date:2007-05-28
Release date:2008-06-10
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational Changes and Loose Packing Promote E. Coli Tryptophanase Cold Lability.
Bmc Struct.Biol., 9, 2009
3HEI
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LIGAND RECOGNITION BY A-CLASS EPH RECEPTORS: CRYSTAL STRUCTURES OF THE EPHA2 LIGAND-BINDING DOMAIN AND THE EPHA2/EPHRIN-A1 COMPLEX
Descriptor:Ephrin type-A receptor 2, Ephrin-A1
Authors:Himanen, J.P., Goldgur, Y., Miao, H., Myshkin, E., Guo, H., Buck, M., Nguyen, M., Rajashankar, K.R., Wang, B., Nikolov, D.B.
Deposit date:2009-05-08
Release date:2009-06-30
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
3HPN
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LIGAND RECOGNITION BY A-CLASS EPH RECEPTORS: CRYSTAL STRUCTURES OF THE EPHA2 LIGAND-BINDING DOMAIN AND THE EPHA2/EPHRIN-A1 COMPLEX
Descriptor:Ephrin type-A receptor 2
Authors:Himanen, J.P., Goldgur, Y., Miao, H., Myshkin, E., Guo, H., Buck, M., Nguyen, M., Rajashankar, K.R., Wang, B., Nikolov, D.B.
Deposit date:2009-06-04
Release date:2009-06-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex.
Embo Rep., 10, 2009
3VFG
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CRYSTAL STRUCTURE OF MONOCLONAL ANTIBODY 3F8 FAB FRAGMENT THAT BINDS TO GD2 GANGLIOSIDE
Descriptor:3F8 Light Chain, 3F8 Heavy Chain
Authors:Ahmed, M., Goldgur, Y., Cheung, N.-K.
Deposit date:2012-01-09
Release date:2013-02-06
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors.
Plos One, 8, 2013
4JYO
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STRUCTURAL BASIS FOR ANGIOPOIETIN-1 MEDIATED SIGNALING INITIATION
Descriptor:Angiopoietin-1, CALCIUM ION
Authors:Yu, X., Seegar, T.C.M., Dalton, A.C., Tzvetkova-Robev, D., Goldgur, Y., Nikolov, D.B., Barton, W.A.
Deposit date:2013-03-31
Release date:2013-05-08
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JZC
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ANGIOPOIETIN-2 FIBRINOGEN DOMAIN TAG MUTANT
Descriptor:Angiopoietin-2
Authors:Yu, X., Seegar, T.C.M., Dalton, A.C., Tzvetkova-Robev, D., Goldgur, Y., Nikolov, D.B., Barton, W.A.
Deposit date:2013-04-02
Release date:2013-05-08
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
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