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6OE5
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SPLAYED OPEN PREFUSION RSV F CAPTURED BY CR9501 AND MOTAVIZUMAB FABS
Descriptor:Fusion glycoprotein F0,Fibritin, Motavizumab Fab Heavy Chain, Motavizumab Fab Light Chain, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2019-03-27
Release date:2019-04-17
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Transient Opening of Trimeric Prefusion RSV F Proteins
Nat Commun, 2019
6APB
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CRYSTAL STRUCTURE OF NON-NEUTRALIZING INFANT ANTIBODY ADI-14359 IN COMPLEX WITH POSTFUSION RSV F GLYCOPROTEIN
Descriptor:Fusion glycoprotein F0,Fusion glycoprotein F0, IgG H chain, ADI-14359 Fab Light Chain, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2017-08-17
Release date:2018-03-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.
Immunity, 48, 2018
6APC
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CRYSTAL STRUCTURE OF INFANT ANTIBODY ADI-19425
Descriptor:Epididymis luminal protein 214, IGL@ protein, SULFATE ION
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2017-08-17
Release date:2018-03-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.
Immunity, 48, 2018
6OE4
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PREFUSION RSV F MONOMER BOUND BY NEUTRALIZING ANTIBODY CR9501
Descriptor:Fusion glycoprotein F0, CR9501 Fab Light Chain, CR9501 Fab Heavy Chain, ...
Authors:McLellan, J.S., Gilman, M.S.A.
Deposit date:2019-03-27
Release date:2019-04-17
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Transient Opening of Trimeric Prefusion RSV F Proteins
Nat Commun, 2019
4ZYK
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CRYSTAL STRUCTURE OF QUATERNARY-SPECIFIC RSV-NEUTRALIZING HUMAN ANTIBODY AM14
Descriptor:AM14 Fab heavy chain, AM14 light chain, SULFATE ION, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-05-21
Release date:2015-07-29
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.
Plos Pathog., 11, 2015
4ZYP
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CRYSTAL STRUCTURE OF MOTAVIZUMAB AND QUATERNARY-SPECIFIC RSV-NEUTRALIZING HUMAN ANTIBODY AM14 IN COMPLEX WITH PREFUSION RSV F GLYCOPROTEIN
Descriptor:Fusion glycoprotein F0,Fibritin, Motavizumab antibody Fab heavy chain, Motavizumab antibody light chain, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-05-21
Release date:2015-07-29
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.
Plos Pathog., 11, 2015
5FHA
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CRYSTAL STRUCTURE OF PROTECTIVE EBOLA VIRUS ANTIBODY 114
Descriptor:Antibody 114 Fab heavy chain, Antibody 114 Fab light chain
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5FHB
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CRYSTAL STRUCTURE OF PROTECTIVE EBOLA VIRUS ANTIBODY 100
Descriptor:Antibody 100 Fab heavy chain, Antibody 100 Fab light chain, 1,2-ETHANEDIOL, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (1.973 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5FHC
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CRYSTAL STRUCTURE OF PROTECTIVE HUMAN ANTIBODIES 100 AND 114 IN COMPLEX WITH EBOLA VIRUS FUSION GLYCOPROTEIN (GP)
Descriptor:Envelope glycoprotein, Envelope glycoprotein,Envelope glycoprotein, Antibody 100 Fab heavy chain, ...
Authors:Gilman, M.S.A., McLellan, J.S.
Deposit date:2015-12-21
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (6.704 Å)
Cite:Structural and molecular basis for Ebola virus neutralization by protective human antibodies.
Science, 351, 2016
5TOJ
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CRYSTAL STRUCTURE OF THE RSV F GLYCOPROTEIN IN COMPLEX WITH THE NEUTRALIZING SINGLE-DOMAIN ANTIBODY F-VHH-4
Descriptor:Fusion glycoprotein F0, Fibritin chimera, Single-domain antibody F-VHH-4, ...
Authors:Gilman, M.S.A., Kabeche, S.C., McLellan, J.S.
Deposit date:2016-10-17
Release date:2017-02-22
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
5TOK
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CRYSTAL STRUCTURE OF THE RSV F GLYCOPROTEIN IN COMPLEX WITH THE NEUTRALIZING SINGLE-DOMAIN ANTIBODY F-VHH-L66
Descriptor:Fusion glycoprotein F0, Fibritin chimera, Single-domain antibody F-VHH-L66, ...
Authors:Gilman, M.S.A., Kabeche, S.C., McLellan, J.S.
Deposit date:2016-10-17
Release date:2017-02-22
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
5TP3
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CRYSTAL STRUCTURE OF THE RSV-NEUTRALIZING SINGLE-DOMAIN ANTIBODY F-VHH-4
Descriptor:F-VHH-4
Authors:Wrapp, D., Gilman, M.S.A., McLellan, J.S.
Deposit date:2016-10-19
Release date:2017-02-22
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.874 Å)
Cite:Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state.
Nat Commun, 8, 2017
6APD
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CRYSTAL STRUCTURE OF RSV F BOUND BY AM22 AND THE INFANT ANTIBODY ADI-19425
Descriptor:Fusion glycoprotein F0,Envelope glycoprotein, AM22 Fab Heavy Chain,IGH@ protein, AM22 Fab Light Chain,Uncharacterized protein, ...
Authors:Wrapp, D., McLellan, J.S.
Deposit date:2017-08-17
Release date:2018-03-21
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Infants Infected with Respiratory Syncytial Virus Generate Potent Neutralizing Antibodies that Lack Somatic Hypermutation.
Immunity, 48, 2018
6BLH
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RSV G CENTRAL CONSERVED REGION BOUND TO FAB CB017.5
Descriptor:Fab CB017.5 light chain, Fab CB017.5 heavy chain, Major surface glycoprotein G, ...
Authors:Jones, H.G., McLellan, J.S., Langedijk, J.P.
Deposit date:2017-11-10
Release date:2018-02-28
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018
6BLI
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RSV G PEPTIDE BOUND TO FAB CB002.5
Descriptor:CB002.5 Fab Heavy Chain, CB002.5 Fab Light Chain, Major surface glycoprotein G
Authors:Jones, H.G., McLellan, J.S., Langedijk, J.P.
Deposit date:2017-11-10
Release date:2018-02-28
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural basis for recognition of the central conserved region of RSV G by neutralizing human antibodies.
PLoS Pathog., 14, 2018