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4PAM
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A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFITE ION, ...
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2014-04-09
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4PAN
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A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFITE ION, ...
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2014-04-09
Release date:2014-07-30
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4PAO
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A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2014-04-09
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
4PAQ
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A CONSERVED PHENYLALANINE AS RELAY BETWEEN THE 5 HELIX AND THE GDP BINDING REGION OF HETEROTRIMERIC G PROTEIN
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2014-04-09
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Conserved Phenylalanine as a Relay between the alpha 5 Helix and the GDP Binding Region of Heterotrimeric Gi Protein alpha Subunit.
J.Biol.Chem., 289, 2014
5KDL
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CRYSTAL STRUCTURE OF THE 4 ALANINE INSERTION VARIANT OF THE GI ALPHA1 SUBUNIT BOUND TO GTPGAMMAS
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, MAGNESIUM ION, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2016-06-08
Release date:2016-08-03
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.665 Å)
Cite:A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor.
J.Biol.Chem., 291, 2016
5KDO
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HETEROTRIMERIC COMPLEX OF THE 4 ALANINE INSERTION VARIANT OF THE GI ALPHA1 SUBUNIT AND THE GBETA1-GGAMMA1
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(T) subunit gamma-T1, ...
Authors:Kaya, A.I., Lokits, A.D., Gilbert, J., Iverson, T.M., Meiler, J., Hamm, H.E.
Deposit date:2016-06-08
Release date:2016-08-03
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Conserved Hydrophobic Core in G alpha i1 Regulates G Protein Activation and Release from Activated Receptor.
J.Biol.Chem., 291, 2016
3HXO
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CRYSTAL STRUCTURE OF VON WILLEBRAND FACTOR (VWF) A1 DOMAIN IN COMPLEX WITH DNA APTAMER ARC1172, AN INHIBITOR OF VWF-PLATELET BINDING
Descriptor:von Willebrand factor, Aptamer ARC1172
Authors:Huang, R.H., Sadler, J.E., Fremont, D.H., Diener, J.L., Schaub, R.G.
Deposit date:2009-06-21
Release date:2009-11-17
Last modified:2012-03-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A structural explanation for the antithrombotic activity of ARC1172, a DNA aptamer that binds von Willebrand factor domain A1.
Structure, 17, 2009
3HXQ
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CRYSTAL STRUCTURE OF VON WILLEBRAND FACTOR (VWF) A1 DOMAIN IN COMPLEX WITH DNA APTAMER ARC1172, AN INHIBITOR OF VWF-PLATELET BINDING
Descriptor:von Willebrand Factor, Aptamer ARC1172
Authors:Huang, R.H., Sadler, J.E., Fremont, D.H., Diener, J.L., Schaub, R.G.
Deposit date:2009-06-21
Release date:2009-11-17
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:A structural explanation for the antithrombotic activity of ARC1172, a DNA aptamer that binds von Willebrand factor domain A1.
Structure, 17, 2009