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1QVX
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SOLUTION STRUCTURE OF THE FAT DOMAIN OF FOCAL ADHESION KINASE
Descriptor:Focal adhesion kinase 1
Authors:Gao, G., Prutzman, K.C., King, M.L., DeRose, E.F., London, R.E., Schaller, M.D., Campbell, S.L.
Deposit date:2003-08-29
Release date:2004-03-02
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase in Complex with a Paxillin LD Peptide: EVIDENCE FOR A TWO-SITE BINDING MODEL.
J.Biol.Chem., 279, 2004
6L1W
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ZINC-FINGER ANTIVIRAL PROTEIN (ZAP) BOUND TO RNA
Descriptor:Zinc finger CCCH-type antiviral protein 1, RNA (5'-R(*CP*GP*UP*CP*GP*U)-3'), ZINC ION
Authors:Luo, X., Wang, X., Gao, Y., Zhu, J., Liu, S., Gao, G., Gao, P.
Deposit date:2019-09-30
Release date:2020-01-01
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein.
Cell Rep, 30, 2020
6U3Q
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THE ATOMIC STRUCTURE OF A HUMAN ADENO-ASSOCIATED VIRUS CAPSID ISOLATE (AAVHU69/AAVV66)
Descriptor:Capsid protein VP1
Authors:Hsu, H.-L., Brown, A., Loveland, A., Tai, P., Korostelev, A., Gao, G.
Deposit date:2019-08-22
Release date:2020-05-27
Last modified:2020-07-15
Method:ELECTRON MICROSCOPY (2.46 Å)
Cite:Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties.
Nat Commun, 11, 2020
1PV3
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NMR SOLUTION STRUCTURE OF THE AVIAN FAT-DOMAIN OF FOCAL ADHESION KINASE
Descriptor:Focal adhesion kinase 1
Authors:Prutzman, K.C., Gao, G., King, M.L., Iyer, V.V., Mueller, G.A., Schaller, M.D., Campbell, S.L.
Deposit date:2003-06-26
Release date:2004-05-25
Last modified:2016-04-27
Method:SOLUTION NMR
Cite:The Focal Adhesion Targeting Domain of Focal Adhesion Kinase Contains a Hinge Region that Modulates Tyrosine 926 Phosphorylation.
STRUCTURE, 12, 2004
1TXD
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF LEUKEMIA-ASSOCIATED RHOGEF
Descriptor:Rho guanine nucleotide exchange factor 12
Authors:Kristelly, R., Gao, G., Tesmer, J.J.
Deposit date:2004-07-03
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
1X86
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CRYSTAL STRUCTURE OF THE DH/PH DOMAINS OF LEUKEMIA-ASSOCIATED RHOGEF IN COMPLEX WITH RHOA
Descriptor:Rho guanine nucleotide exchange factor 12, Transforming protein RhoA, PHOSPHATE ION
Authors:Kristelly, R., Gao, G., Tesmer, J.J.
Deposit date:2004-08-17
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
J.Biol.Chem., 279, 2004
3U9G
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CRYSTAL STRUCTURE OF THE ZINC FINGER ANTIVIRAL PROTEIN
Descriptor:Zinc finger CCCH-type antiviral protein 1, ZINC ION
Authors:Chen, S., Xu, Y., Zhang, K., Wang, X., Sun, J., Gao, G., Liu, Y.
Deposit date:2011-10-18
Release date:2012-03-14
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA.
Nat.Struct.Mol.Biol., 19, 2012
3V32
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CRYSTAL STRUCTURE OF MCPIP1 N-TERMINAL CONSERVED DOMAIN
Descriptor:Ribonuclease ZC3H12A
Authors:Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., Rao, Z.
Deposit date:2011-12-12
Release date:2012-05-23
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
3V33
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CRYSTAL STRUCTURE OF MCPIP1 CONSERVED DOMAIN WITH ZINC-FINGER MOTIF
Descriptor:Ribonuclease ZC3H12A
Authors:Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., Rao, Z.
Deposit date:2011-12-12
Release date:2012-05-23
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
3V34
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CRYSTAL STRUCTURE OF MCPIP1 CONSERVED DOMAIN WITH MAGNESIUM ION IN THE CATALYTIC CENTER
Descriptor:Ribonuclease ZC3H12A, MAGNESIUM ION
Authors:Xu, J., Peng, W., Sun, Y., Wang, X., Xu, Y., Li, X., Gao, G., Rao, Z.
Deposit date:2011-12-12
Release date:2012-05-23
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (2.003 Å)
Cite:Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase
Nucleic Acids Res., 40, 2012
4MX1
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STRUCTURE OF RICIN A CHAIN BOUND WITH 2-AMINO-4-OXO-N-(2-(3-PHENYLUREIDO)ETHYL)-3,4-DIHYDROPTERIDINE-7-CARBOXAMIDE
Descriptor:Ricin A chain, 2-amino-4-oxo-N-{2-[(phenylcarbamoyl)amino]ethyl}-3,4-dihydropteridine-7-carboxamide, SULFATE ION, ...
Authors:Robertus, J.D., Wiget, P.A., Manzano, L.A., Pruet, J.M., Gao, G., Saito, R., Jasheway, K.R., Monzingo, A.F., Anslyn, E.V.
Deposit date:2013-09-25
Release date:2014-01-15
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics.
Bioorg.Med.Chem.Lett., 23, 2013
4MX5
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STRUCTURE OF RICIN A CHAIN BOUND WITH BENZYL-(2-(2-AMINO-4-OXO-3,4-DIHYDROPTERIDINE-7-CARBOXAMIDO)ETHYL)CARBAMATE
Descriptor:Ricin A chain, benzyl (2-{[(2-amino-4-oxo-3,4-dihydropteridin-7-yl)carbonyl]amino}ethyl)carbamate
Authors:Jasheway, K.R., Robertus, J.D., Wiget, P.A., Manzano, L.A., Pruet, J.M., Gao, G., Saito, R., Monzingo, A.F., Anslyn, E.V.
Deposit date:2013-09-25
Release date:2014-01-15
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Sulfur incorporation generally improves Ricin inhibition in pterin-appended glycine-phenylalanine dipeptide mimics.
Bioorg.Med.Chem.Lett., 23, 2013
4WJA
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CRYSTAL STRUCTURE OF PAXX
Descriptor:Uncharacterized protein C9orf142
Authors:Xing, M., Yang, M., Huo, W., Feng, F., Wei, L., Ning, S., Yan, Z., Li, W., Wang, Q., Hou, M., Dong, C., Guo, R., Gao, G., Ji, J., Lan, L., Liang, H., Xu, D.
Deposit date:2014-09-29
Release date:2015-03-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway.
Nat Commun, 6, 2015
6I2M
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CRYSTAL STRUCTURE OF VACCINIA VIRUS PROTEIN A55 BTB-BACK DOMAIN IN COMPLEX WITH HUMAN CULLIN-3 N-TERMINUS
Descriptor:Kelch repeat and BTB domain-containing protein A55, Cullin-3
Authors:Gao, G., Graham, S.C.
Deposit date:2018-11-01
Release date:2019-01-23
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular basis of cullin-3 (Cul3) ubiquitin ligase subversion by vaccinia virus protein A55.
J.Biol.Chem., 294, 2019
6J9K
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APO-ACRIIC2
Descriptor:AcrIIC2, MAGNESIUM ION
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (2.234 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 74, 2019
6J9L
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FNOBH+ACRIIC2
Descriptor:AcrIIC2, HNH endonuclease family protein
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 74, 2019
6J9M
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NMEBH+ACRIIC2
Descriptor:CRISPR-associated endonuclease Cas9, AcrIIC2
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (2.394 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 74, 2019
6J9N
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NMEHNH+ACRIIC3
Descriptor:CRISPR-associated endonuclease Cas9, AcrIIC3
Authors:Zhu, Y.L., Gao, A., Serganov, A., Gao, P.
Deposit date:2019-01-23
Release date:2019-03-06
Last modified:2019-05-01
Method:X-RAY DIFFRACTION (2.606 Å)
Cite:Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins.
Mol. Cell, 74, 2019
7C01
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MOLECULAR BASIS FOR A POTENT HUMAN NEUTRALIZING ANTIBODY TARGETING SARS-COV-2 RBD
Descriptor:SARS-Cov-2 Spike protein S1, CB6 heavy chain, CB6 light chain, ...
Authors:Shi, R., Qi, J., Wang, Q., Gao, F.G., Yan, J.
Deposit date:2020-04-29
Release date:2020-05-27
Last modified:2020-08-19
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2.
Nature, 584, 2020
4NFB
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STRUCTURE OF PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR (PILR )
Descriptor:Paired immunoglobulin-like type 2 receptor alpha
Authors:Lu, Q., Lu, G., Qi, J., Li, Y., Zhang, Y., Wang, H., Fan, Z., Yan, J., Gao, G.
Deposit date:2013-10-31
Release date:2014-05-28
Last modified:2014-09-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:PILR alpha and PILR beta have a siglec fold and provide the basis of binding to sialic acid
Proc.Natl.Acad.Sci.USA, 111, 2014
7BXF
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MVCA-LPG2149 COMPLEX
Descriptor:MvcA, Lpg2149, PRASEODYMIUM ION
Authors:Gao, P.
Deposit date:2020-04-19
Release date:2020-05-20
Last modified:2020-09-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
7BXG
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MAVC-UBE2N-UB COMPLEX
Descriptor:MavC, Ubiquitin-conjugating enzyme E2 N, Polyubiquitin-C
Authors:Gao, P., Wang, Y.
Deposit date:2020-04-19
Release date:2020-05-20
Last modified:2020-09-09
Method:X-RAY DIFFRACTION (2.705 Å)
Cite:Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
7BXH
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MAVC-LPG2149 COMPLEX
Descriptor:Lpg2149, MavC
Authors:Gao, P., Wang, Y.
Deposit date:2020-04-19
Release date:2020-05-20
Last modified:2020-09-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
4KPQ
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STRUCTURE AND RECEPTOR BINDING SPECIFICITY OF THE HEMAGGLUTININ H13 FROM AVIAN INFLUENZA A VIRUS H13N6
Descriptor:Hemagglutinin, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Lu, X., Qi, J., Shi, Y., Gao, G.
Deposit date:2013-05-14
Release date:2013-07-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.502 Å)
Cite:Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6
J.Virol., 87, 2013
4KPS
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STRUCTURE AND RECEPTOR BINDING SPECIFICITY OF THE HEMAGGLUTININ H13 FROM AVIAN INFLUENZA A VIRUS H13N6
Descriptor:Hemagglutinin, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Lu, X., Qi, J., Shi, Y., Gao, G.
Deposit date:2013-05-14
Release date:2013-07-03
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.587 Å)
Cite:Structure and Receptor Binding Specificity of Hemagglutinin H13 from Avian Influenza A Virus H13N6
J.Virol., 87, 2013
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