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1GAX
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BU of 1gax by Molmil
CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS VALYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(VAL) AND VALYL-ADENYLATE ANALOGUE
Descriptor: N-[VALINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, TRNA(VAL), VALYL-TRNA SYNTHETASE, ...
Authors:Fukai, S, Nureki, O, Sekine, S, Shimada, A, Tao, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2000-06-23
Release date:2000-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for double-sieve discrimination of L-valine from L-isoleucine and L-threonine by the complex of tRNA(Val) and valyl-tRNA synthetase.
Cell(Cambridge,Mass.), 103, 2000
1IVS
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BU of 1ivs by Molmil
CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS VALYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(VAL) AND VALYL-ADENYLATE ANALOGUE
Descriptor: N-[VALINYL]-N'-[ADENOSYL]-DIAMINOSUFONE, Valyl-tRNA synthetase, tRNA (Val)
Authors:Fukai, S, Nureki, O, Sekine, S.-I, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-03-29
Release date:2003-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase
RNA, 9, 2003
1UAD
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BU of 1uad by Molmil
Crystal structure of the RalA-GppNHp-Sec5 Ral-binding domain complex
Descriptor: Exocyst complex component Sec5, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ...
Authors:Fukai, S, Matern, H.T, Scheller, R.H, Brunger, A.T.
Deposit date:2003-03-09
Release date:2003-07-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of the interaction between RalA and Sec5, a subunit of the Sec6/8 complex
EMBO J., 22, 2003
1IYW
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BU of 1iyw by Molmil
Preliminary Structure of Thermus thermophilus Ligand-Free Valyl-tRNA Synthetase
Descriptor: Valyl-tRNA Synthetase
Authors:Fukai, S, Nureki, O, Sekine, S, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2002-09-10
Release date:2003-06-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (4 Å)
Cite:Mechanism of molecular interactions for tRNA(Val) recognition by valyl-tRNA synthetase
RNA, 9, 2003
2E7S
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BU of 2e7s by Molmil
Crystal structure of the yeast Sec2p GEF domain
Descriptor: Rab guanine nucleotide exchange factor SEC2
Authors:Fukai, S, Sato, Y, Nureki, O.
Deposit date:2007-01-12
Release date:2007-02-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Asymmetric Coiled-Coil Structure with Guanine Nucleotide Exchange Activity
Structure, 15, 2007
4UBQ
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BU of 4ubq by Molmil
Crystal Structure of IMP-2 Metallo-beta-Lactamase from Acinetobacter spp.
Descriptor: ACETATE ION, Beta-lactamase, ZINC ION
Authors:Yamaguchi, Y, Matsueda, S, Matsunaga, K, Takashio, N, Toma-Fukai, S, Yamagata, Y, Shibata, N, Wachino, J, Shibayama, K, Arakawa, Y, Kurosaki, H.
Deposit date:2014-08-13
Release date:2014-12-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of IMP-2 metallo-beta-lactamase from Acinetobacter spp.: comparison of active-site loop structures between IMP-1 and IMP-2.
Biol.Pharm.Bull., 38, 2015
7BY1
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BU of 7by1 by Molmil
Crystal structure of GCN5 PCAF N-terminal domain
Descriptor: Histone acetyltransferase KAT2A, ZINC ION
Authors:Hibi, R, Toma-Fukai, S, Shimizu, T.
Deposit date:2020-04-21
Release date:2020-08-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure.
J.Biol.Chem., 295, 2020
8J6N
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BU of 8j6n by Molmil
Crystal structure of Cystathionine gamma-lyase in complex with compound 1
Descriptor: 1,2-ETHANEDIOL, Cystathionine gamma-lyase, GLYCEROL, ...
Authors:Hibi, R, Toma-Fukai, S, Shimizu, T, Hanaoka, K.
Deposit date:2023-04-26
Release date:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of a cystathionine gamma-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5'-phosphate (PLP) via Schiff base formation.
Sci Rep, 13, 2023
5DST
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BU of 5dst by Molmil
Crystal structure of human PRMT8 in complex with SAH
Descriptor: Protein arginine N-methyltransferase 8, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Toma-Fukai, S, Shimizu, T.
Deposit date:2015-09-17
Release date:2016-02-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.963 Å)
Cite:Novel helical assembly in arginine methyltransferase 8
J.Mol.Biol., 428, 2016
5ZHX
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BU of 5zhx by Molmil
Crystal structure of SmgGDS-558 and farnesylated RhoA complex
Descriptor: FARNESYL, Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA
Authors:Shimizu, H, Toma-Fukai, S, Shimizu, T.
Deposit date:2018-03-13
Release date:2018-09-05
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YJ9
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BU of 5yj9 by Molmil
Crystal structure of Tribolium castaneum PINK1 kinase domain in complex with AMP-PNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PINK1, ...
Authors:Okatsu, K, Sato, Y, Fukai, S.
Deposit date:2017-10-09
Release date:2018-07-25
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural insights into ubiquitin phosphorylation by PINK1.
Sci Rep, 8, 2018
5Z8X
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BU of 5z8x by Molmil
Crystal structure of human LRRTM2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leucine-rich repeat transmembrane neuronal protein 2
Authors:Yamagata, A, Fukai, S.
Deposit date:2018-02-01
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.
Nat Commun, 9, 2018
5Z8Y
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BU of 5z8y by Molmil
Crystal structure of human LRRTM2 in complex with Neurexin 1beta
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Yamagata, A, Fukai, S.
Deposit date:2018-02-01
Release date:2018-10-10
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural insights into modulation and selectivity of transsynaptic neurexin-LRRTM interaction.
Nat Commun, 9, 2018
2EQB
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BU of 2eqb by Molmil
Crystal structure of the Rab GTPase Sec4p, the Sec2p GEF domain, and phosphate complex
Descriptor: PHOSPHATE ION, Rab guanine nucleotide exchange factor SEC2, Ras-related protein SEC4
Authors:Sato, Y, Fukai, S, Ishitani, R, Nureki, O.
Deposit date:2007-03-30
Release date:2007-05-22
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Sec4p{middle dot}Sec2p complex in the nucleotide exchanging intermediate state
Proc.Natl.Acad.Sci.Usa, 104, 2007
5ZNM
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BU of 5znm by Molmil
Colicin D Central Domain and C-terminal tRNase domain
Descriptor: Colicin-D, GLYCEROL, SULFATE ION
Authors:Chang, J.W, Sato, Y, Ogawa, T, Arakawa, T, Fukai, S, Fushinobu, S, Masaki, H.
Deposit date:2018-04-10
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the central and the C-terminal RNase domains of colicin D implicated its translocation pathway through inner membrane of target cell
J. Biochem., 164, 2018
3JSV
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BU of 3jsv by Molmil
Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin
Descriptor: NF-kappa-B essential modulator, Ubiquitin
Authors:Yoshikawa, A, Sato, Y, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S.
Deposit date:2009-09-11
Release date:2009-10-27
Last modified:2021-11-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
Febs Lett., 583, 2009
6A6I
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BU of 6a6i by Molmil
Crystal structure of the winged-helix domain of Cockayne syndrome group B protein in complex with ubiquitin
Descriptor: CHLORIDE ION, Excision repair cross-complementing rodent repair deficiency, complementation group 6 variant, ...
Authors:Takahashi, T.S, Sato, Y, Fukai, S.
Deposit date:2018-06-28
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis of ubiquitin recognition by the winged-helix domain of Cockayne syndrome group B protein.
Nucleic Acids Res., 47, 2019
3B2E
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BU of 3b2e by Molmil
Crystal structure of S. cerevisiae Get3 in the open conformation in complex with Get1 cytosolic domain
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATPase GET3, Golgi to ER traffic protein 1
Authors:Kubota, K, Yamagata, A, Fukai, S.
Deposit date:2011-07-30
Release date:2012-06-27
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Get1 stabilizes an open dimer conformation of get3 ATPase by binding two distinct interfaces
J.Mol.Biol., 422, 2012
4WU5
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BU of 4wu5 by Molmil
HLA-A24 in complex with HIV-1 Nef134-8(wt)
Descriptor: 8-Mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shimizu, A, Yamagata, A, Fukai, S, Iwamoto, A.
Deposit date:2014-10-31
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Nef134-8(wt) epitope presented by HLA-A24
To Be Published
4WU7
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BU of 4wu7 by Molmil
HLA-A24 in complex with HIV-1 Nef134-8(2F)
Descriptor: 8-Mer peptide from Protein Nef, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Shimizu, A, Yamagata, A, Fukai, S, Iwamoto, A.
Deposit date:2014-10-31
Release date:2015-05-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Crystal structure of Nef134-8 epitope presented by HLA-A24
To Be Published
1VFG
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BU of 1vfg by Molmil
Crystal structure of tRNA nucleotidyltransferase complexed with a primer tRNA and an incoming ATP analog
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, RNA (75-MER), poly A polymerase
Authors:Tomita, K, Fukai, S, Ishitani, R, Ueda, T, Takeuchi, N, Vassylyev, D.G, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-04-13
Release date:2004-08-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for template-independent RNA polymerization.
Nature, 430, 2004
1WY5
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BU of 1wy5 by Molmil
Crystal structure of isoluecyl-tRNA lysidine synthetase
Descriptor: Hypothetical UPF0072 protein AQ_1887
Authors:Nakanishi, K, Fukai, S, Ikeuchi, Y, Soma, A, Sekine, Y, Suzuki, T, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-02-06
Release date:2005-05-03
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural basis for lysidine formation by ATP pyrophosphatase accompanied by a lysine-specific loop and a tRNA-recognition domain.
Proc.Natl.Acad.Sci.Usa, 102, 2005
3B08
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BU of 3b08 by Molmil
Crystal structure of the mouse HOIL1-L-NZF in complex with linear di-ubiquitin
Descriptor: Polyubiquitin-C, RanBP-type and C3HC4-type zinc finger-containing protein 1, ZINC ION, ...
Authors:Sato, Y, Fujita, H, Yoshikawa, A, Yamashita, M, Yamagata, A, Kaiser, S.E, Iwai, K, Fukai, S.
Deposit date:2011-06-07
Release date:2011-12-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex
Proc.Natl.Acad.Sci.USA, 108, 2011
7W86
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BU of 7w86 by Molmil
Crystal structure of the DYW domain of DYW1
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, GLYCEROL, ...
Authors:Sawada, Y, Shimizu, H, Toma-Fukai, S, Shimizu, T.
Deposit date:2021-12-07
Release date:2022-12-14
Last modified:2023-06-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insight into the activation of an Arabidopsis organellar C-to-U RNA editing enzyme by active site complementation.
Plant Cell, 35, 2023
5GVC
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BU of 5gvc by Molmil
Human Topoisomerase IIIb topo domain
Descriptor: DNA topoisomerase 3-beta-1, MAGNESIUM ION
Authors:Goto-Ito, S, Yamagata, A, Sato, Y, Takahashi, T.S, Fukai, S.
Deposit date:2016-09-05
Release date:2017-06-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.436 Å)
Cite:Structural basis of the interaction between Topoisomerase III beta and the TDRD3 auxiliary factor
Sci Rep, 7, 2017

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