Author results

1FUG
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S-ADENOSYLMETHIONINE SYNTHETASE
Descriptor:S-ADENOSYLMETHIONINE SYNTHETASE
Authors:Fu, Z., Markham, G.D., Takusagawa, F.
Deposit date:1996-02-25
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Flexible loop in the structure of S-adenosylmethionine synthetase crystallized in the tetragonal modification.
J.Biomol.Struct.Dyn., 13, 1996
1KVK
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THE STRUCTURE OF BINARY COMPLEX BETWEEN A MAMMALIAN MEVALONATE KINASE AND ATP: INSIGHTS INTO THE REACTION MECHANISM AND HUMAN INHERITED DISEASE
Descriptor:mevalonate kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Fu, Z., Wang, M., Potter, D., Mizioko, H.M., Kim, J.J.
Deposit date:2002-01-26
Release date:2002-03-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
1XVA
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METHYLTRANSFERASE
Descriptor:GLYCINE N-METHYLTRANSFERASE, ACETATE ION, S-ADENOSYLMETHIONINE
Authors:Fu, Z., Hu, Y., Konishi, K., Takata, Y., Ogawa, H., Gomi, T., Fujioka, M., Takusagawa, F.
Deposit date:1996-07-20
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of glycine N-methyltransferase from rat liver.
Biochemistry, 35, 1996
2CW6
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CRYSTAL STRUCTURE OF HUMAN HMG-COA LYASE: INSIGHTS INTO CATALYSIS AND THE MOLECULAR BASIS FOR HYDROXYMETHYLGLUTARIC ACIDURIA
Descriptor:Hydroxymethylglutaryl-CoA lyase, mitochondrial, MAGNESIUM ION, ...
Authors:Fu, Z., Runquist, J.A., Hunt, J.F., Miziorko, H.M., Kim, J.-J.P.
Deposit date:2005-06-17
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human 3-hydroxy-3-methylglutaryl-CoA Lyase: insights into catalysis and the molecular basis for hydroxymethylglutaric aciduria
J.Biol.Chem., 281, 2006
2G7K
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STRUCTURE OF THE LIGHT CHAIN OF BOTULINUM NEUROTOXIN, SEROTYPE A BOUND TO SMALL MOLECULE INHIBITORS
Descriptor:Botulinum neurotoxin type A
Authors:Fu, Z., Baldwin, M.R., Boldt, G.E., Crawford, A., Janda, K.D., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
2G7N
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STRUCTURE OF THE LIGHT CHAIN OF BOTULINUM NEUROTOXIN SEROTYPE A BOUND TO SMALL MOLECULE INHIBITORS
Descriptor:Botulinum neurotoxin type A, ZINC ION, SILVER ION
Authors:Fu, Z., Baldwin, M.R., Boldt, G.E., Janda, K.D., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Light Chain of Botulinum Neurotoxin Serotype A bound to Small Molecule Inhibitors
To be Published
2G7P
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STRUCTURE OF THE LIGHT CHAIN OF BOTULINUM NEUROTOXIN SEROTYPE A BOUND TO SMALL MOLECULE INHIBITORS
Descriptor:Botulinum neurotoxin type A, ZINC ION
Authors:Fu, Z., Baldwin, M.R., Boldt, G.E., Janda, K.D., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
2G7Q
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STRUCTURE OF THE LIGHT CHAIN OF BOTULINUM NEUROTOXIN SEROTYPE A BOUND TO SMALL MOLECULE INHIBITORS
Descriptor:Botulinum neurotoxin type A, ZINC ION, N-HYDROXY-L-ARGININAMIDE
Authors:Fu, Z., Baldwin, M.R., Boldt, G.E., Janda, K.D., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
2R3V
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THE BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF MEVALONATE KINASE AND ISOPRENOID METABOLISM
Descriptor:Mevalonate kinase
Authors:Fu, Z., Voynova, N.E., Miziorko, H.M., Kim, J.P.
Deposit date:2007-08-30
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism.
Biochemistry, 47, 2008
2R42
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THE BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF MEVALONATE KINASE AND ISOPRENOID METABOLISM
Descriptor:Mevalonate kinase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
Authors:Fu, Z., Voynova, N.E., Miziorko, H.M., Kim, J.P.
Deposit date:2007-08-30
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism.
Biochemistry, 47, 2008
3FUO
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THE CRYSTAL STRUCTURE OF RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN SEROTYPE A
Descriptor:Botulinum neurotoxin type A
Authors:Fu, Z., Chen, C., Barbieri, J.T., Kim, J.-J.P., Baldwin, M.R.
Deposit date:2009-01-14
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Biochemistry, 48, 2009
3FUQ
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GLYCOSYLATED SV2 AND GANGLIOSIDES AS DUAL RECEPTORS FOR BOTULINUM NEUROTOXIN SEROTYPE F
Descriptor:BoNT/F (Neurotoxin type F)
Authors:Fu, Z., Chen, C., Barbieri, J.T., Kim, J.-J.P., Baldwin, M.R.
Deposit date:2009-01-14
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Biochemistry, 48, 2009
3MP3
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CRYSTAL STRUCTURE OF HUMAN LYASE IN COMPLEX WITH INHIBITOR HG-COA
Descriptor:Hydroxymethylglutaryl-CoA lyase, 3-HYDROXYPENTANEDIOIC ACID, MAGNESIUM ION, ...
Authors:Fu, Z., Runquist, J.A., Montgomery, C., Miziorko, H.M., Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
3MP4
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CRYSTAL STRUCTURE OF HUMAN LYASE R41M MUTANT
Descriptor:Hydroxymethylglutaryl-CoA lyase
Authors:Fu, Z., Runquist, J.A., Montgomery, C., Miziorko, H.M., Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
3MP5
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CRYSTAL STRUCTURE OF HUMAN LYASE R41M IN COMPLEX WITH HMG-COA
Descriptor:Hydroxymethylglutaryl-CoA lyase, 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, MAGNESIUM ION
Authors:Fu, Z., Runquist, J.A., Montgomery, C., Miziorko, H.M., Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
1SIQ
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THE CRYSTAL STRUCTURE AND MECHANISM OF HUMAN GLUTARYL-COA DEHYDROGENASE
Descriptor:Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Wang, M., Fu, Z., Paschke, R., Goodman, S., Frerman, F.E., Kim, J.J.
Deposit date:2004-03-01
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions
Biochemistry, 43, 2004
1SIR
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THE CRYSTAL STRUCTURE AND MECHANISM OF HUMAN GLUTARYL-COA DEHYDROGENASE
Descriptor:Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, S-4-NITROBUTYRYL-COA
Authors:Wang, M., Fu, Z., Paschke, R., Goodman, S.L., Frerman, F.E., Kim, J.J.
Deposit date:2004-03-01
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions
Biochemistry, 43, 2004
3N7J
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE D BINDING DOMAIN
Descriptor:Botulinum neurotoxin type D
Authors:Fu, Z., Baldwin, M.R., Karalewitz, A., Kroken, A., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2010-05-27
Release date:2010-09-08
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .
Biochemistry, 49, 2010
3N7K
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE C1 BINDING DOMAIN
Descriptor:Botulinum neurotoxin type C1
Authors:Fu, Z., Kroken, A., Karalewitz, A., Baldwin, M.R., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2010-05-27
Release date:2010-09-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .
Biochemistry, 49, 2010
3N7L
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CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE D/C VPI 5993 BINDING DOMAIN
Descriptor:Neurotoxin, SULFATE ION, GLYCEROL
Authors:Fu, Z., Karalewitz, A., Kroken, A., Baldwin, M.R., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2010-05-27
Release date:2010-09-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .
Biochemistry, 49, 2010
3N7M
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CRYSTAL STRUCTURE OF W1252A MUTANT OF HCR D/C VPI 5995
Descriptor:Neurotoxin, SULFATE ION, GLYCEROL
Authors:Fu, Z., Karalewitz, A., Kroken, A., Baldwin, M.R., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2010-05-27
Release date:2010-09-08
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .
Biochemistry, 49, 2010
3RMX
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CRYSTAL STRUCTURE OF HCR/D F1240A MUTANT
Descriptor:Botulinum neurotoxin type D
Authors:Fu, Z., Karalewitz, A., Kroken, A., Kim, J.-J.P., Barbieri, J.T.
Deposit date:2011-04-21
Release date:2011-06-01
Last modified:2015-02-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons.
J.Biol.Chem., 286, 2011
3RMY
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CRYSTAL STRUCTURE OF HCR/D W1238A MUTANT
Descriptor:Botulinum neurotoxin type D, GLYCEROL
Authors:Fu, Z., Karalewitz, A., Kroken, A., Kim, J.-J.P., Barbieri, J.T.
Deposit date:2011-04-21
Release date:2011-06-01
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Novel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into Neurons.
J.Biol.Chem., 286, 2011
3RSJ
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STRUCTURE OF HCRF IN COMPLEX WITH GANGLIOSIDE GD1A
Descriptor:BoNT/F, N-ACETYL-D-GALACTOSAMINE, BETA-D-GALACTOSE, ...
Authors:Fu, Z., Benson, M.A., Barbieri, J.T., Kim, J.-J.P., Baldwin, M.R.
Deposit date:2011-05-02
Release date:2011-08-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Unique ganglioside recognition strategies for clostridial neurotoxins.
J.Biol.Chem., 286, 2011
4FVV
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CRYSTAL STRUCTURE OF HCR/D-SA-GBL1/C
Descriptor:Neurotoxin, SULFATE ION, GLYCEROL, ...
Authors:Fu, Z., Karalewitz, A., Baldwin, M.R., Kim, J.-J.P., Barbieri, J.T.
Deposit date:2012-06-29
Release date:2012-10-24
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
J.Biol.Chem., 287, 2012
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