Author results

1FUG
  • Download 1fug
  • View 1fug
Molmil generated image of 1fug
S-ADENOSYLMETHIONINE SYNTHETASE
Descriptor:S-ADENOSYLMETHIONINE SYNTHETASE
Authors:Fu, Z., Markham, G.D., Takusagawa, F.
Deposit date:1996-02-25
Release date:1996-08-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Flexible loop in the structure of S-adenosylmethionine synthetase crystallized in the tetragonal modification.
J.Biomol.Struct.Dyn., 13, 1996
1KVK
  • Download 1kvk
  • View 1kvk
Molmil generated image of 1kvk
THE STRUCTURE OF BINARY COMPLEX BETWEEN A MAMMALIAN MEVALONATE KINASE AND ATP: INSIGHTS INTO THE REACTION MECHANISM AND HUMAN INHERITED DISEASE
Descriptor:mevalonate kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Fu, Z., Wang, M., Potter, D., Mizioko, H.M., Kim, J.J.
Deposit date:2002-01-26
Release date:2002-03-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
1XVA
  • Download 1xva
  • View 1xva
Molmil generated image of 1xva
METHYLTRANSFERASE
Descriptor:GLYCINE N-METHYLTRANSFERASE, ACETATE ION, S-ADENOSYLMETHIONINE
Authors:Fu, Z., Hu, Y., Konishi, K., Takata, Y., Ogawa, H., Gomi, T., Fujioka, M., Takusagawa, F.
Deposit date:1996-07-20
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of glycine N-methyltransferase from rat liver.
Biochemistry, 35, 1996
2CW6
  • Download 2cw6
  • View 2cw6
Molmil generated image of 2cw6
CRYSTAL STRUCTURE OF HUMAN HMG-COA LYASE: INSIGHTS INTO CATALYSIS AND THE MOLECULAR BASIS FOR HYDROXYMETHYLGLUTARIC ACIDURIA
Descriptor:Hydroxymethylglutaryl-CoA lyase, mitochondrial, MAGNESIUM ION, ...
Authors:Fu, Z., Runquist, J.A., Hunt, J.F., Miziorko, H.M., Kim, J.-J.P.
Deposit date:2005-06-17
Release date:2005-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of human 3-hydroxy-3-methylglutaryl-CoA Lyase: insights into catalysis and the molecular basis for hydroxymethylglutaric aciduria
J.Biol.Chem., 281, 2006
2G7K
  • Download 2g7k
  • View 2g7k
Molmil generated image of 2g7k
STRUCTURE OF THE LIGHT CHAIN OF BOTULINUM NEUROTOXIN, SEROTYPE A BOUND TO SMALL MOLECULE INHIBITORS
Descriptor:Botulinum neurotoxin type A
Authors:Fu, Z., Baldwin, M.R., Boldt, G.E., Crawford, A., Janda, K.D., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
2G7N
  • Download 2g7n
  • View 2g7n
Molmil generated image of 2g7n
STRUCTURE OF THE LIGHT CHAIN OF BOTULINUM NEUROTOXIN SEROTYPE A BOUND TO SMALL MOLECULE INHIBITORS
Descriptor:Botulinum neurotoxin type A, ZINC ION, SILVER ION
Authors:Fu, Z., Baldwin, M.R., Boldt, G.E., Janda, K.D., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Light Chain of Botulinum Neurotoxin Serotype A bound to Small Molecule Inhibitors
To be Published
2G7P
  • Download 2g7p
  • View 2g7p
Molmil generated image of 2g7p
STRUCTURE OF THE LIGHT CHAIN OF BOTULINUM NEUROTOXIN SEROTYPE A BOUND TO SMALL MOLECULE INHIBITORS
Descriptor:Botulinum neurotoxin type A, ZINC ION
Authors:Fu, Z., Baldwin, M.R., Boldt, G.E., Janda, K.D., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
2G7Q
  • Download 2g7q
  • View 2g7q
Molmil generated image of 2g7q
STRUCTURE OF THE LIGHT CHAIN OF BOTULINUM NEUROTOXIN SEROTYPE A BOUND TO SMALL MOLECULE INHIBITORS
Descriptor:Botulinum neurotoxin type A, ZINC ION, N-HYDROXY-L-ARGININAMIDE
Authors:Fu, Z., Baldwin, M.R., Boldt, G.E., Janda, K.D., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2006-02-28
Release date:2006-08-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate.
Biochemistry, 45, 2006
2R3V
  • Download 2r3v
  • View 2r3v
Molmil generated image of 2r3v
THE BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF MEVALONATE KINASE AND ISOPRENOID METABOLISM
Descriptor:Mevalonate kinase
Authors:Fu, Z., Voynova, N.E., Miziorko, H.M., Kim, J.P.
Deposit date:2007-08-30
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism.
Biochemistry, 47, 2008
2R42
  • Download 2r42
  • View 2r42
Molmil generated image of 2r42
THE BIOCHEMICAL AND STRUCTURAL BASIS FOR FEEDBACK INHIBITION OF MEVALONATE KINASE AND ISOPRENOID METABOLISM
Descriptor:Mevalonate kinase, MAGNESIUM ION, S-[(2E,6E)-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENYL] TRIHYDROGEN THIODIPHOSPHATE
Authors:Fu, Z., Voynova, N.E., Miziorko, H.M., Kim, J.P.
Deposit date:2007-08-30
Release date:2008-06-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Biochemical and Structural Basis for Feedback Inhibition of Mevalonate Kinase and Isoprenoid Metabolism.
Biochemistry, 47, 2008
3FUO
  • Download 3fuo
  • View 3fuo
Molmil generated image of 3fuo
THE CRYSTAL STRUCTURE OF RECEPTOR BINDING DOMAIN OF BOTULINUM NEUROTOXIN SEROTYPE A
Descriptor:Botulinum neurotoxin type A
Authors:Fu, Z., Chen, C., Barbieri, J.T., Kim, J.-J.P., Baldwin, M.R.
Deposit date:2009-01-14
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Biochemistry, 48, 2009
3FUQ
  • Download 3fuq
  • View 3fuq
Molmil generated image of 3fuq
GLYCOSYLATED SV2 AND GANGLIOSIDES AS DUAL RECEPTORS FOR BOTULINUM NEUROTOXIN SEROTYPE F
Descriptor:BoNT/F (Neurotoxin type F)
Authors:Fu, Z., Chen, C., Barbieri, J.T., Kim, J.-J.P., Baldwin, M.R.
Deposit date:2009-01-14
Release date:2009-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F
Biochemistry, 48, 2009
3MP3
  • Download 3mp3
  • View 3mp3
Molmil generated image of 3mp3
CRYSTAL STRUCTURE OF HUMAN LYASE IN COMPLEX WITH INHIBITOR HG-COA
Descriptor:Hydroxymethylglutaryl-CoA lyase, 3-HYDROXYPENTANEDIOIC ACID, MAGNESIUM ION, ...
Authors:Fu, Z., Runquist, J.A., Montgomery, C., Miziorko, H.M., Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
3MP4
  • Download 3mp4
  • View 3mp4
Molmil generated image of 3mp4
CRYSTAL STRUCTURE OF HUMAN LYASE R41M MUTANT
Descriptor:Hydroxymethylglutaryl-CoA lyase
Authors:Fu, Z., Runquist, J.A., Montgomery, C., Miziorko, H.M., Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
3MP5
  • Download 3mp5
  • View 3mp5
Molmil generated image of 3mp5
CRYSTAL STRUCTURE OF HUMAN LYASE R41M IN COMPLEX WITH HMG-COA
Descriptor:Hydroxymethylglutaryl-CoA lyase, 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A, MAGNESIUM ION
Authors:Fu, Z., Runquist, J.A., Montgomery, C., Miziorko, H.M., Kim, J.-J.P.
Deposit date:2010-04-24
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes.
J.Biol.Chem., 285, 2010
6ORE
  • Download 6ore
  • View 6ore
Molmil generated image of 6ore
RELEASE COMPLEX 70S
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z.
Deposit date:2019-04-30
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6ORL
  • Download 6orl
  • View 6orl
Molmil generated image of 6orl
RF1 PRE-ACCOMMODATED 70S COMPLEX AT 24 MS
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-04-30
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OSK
  • Download 6osk
  • View 6osk
Molmil generated image of 6osk
RF1 ACCOMMODATED 70S COMPLEX AT 60 MS
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-01
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OSQ
  • Download 6osq
  • View 6osq
Molmil generated image of 6osq
RF1 ACCOMMODATED STATE BOUND RELEASE COMPLEX 70S AT LONG INCUBATION TIME POINT
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-02
Release date:2019-06-26
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OST
  • Download 6ost
  • View 6ost
Molmil generated image of 6ost
RF2 PRE-ACCOMMODATED STATE BOUND RELEASE COMPLEX 70S AT 24MS
Descriptor:23S Ribosomal RNA, 16S Ribosomal RNA, 5S Ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-02
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OT3
  • Download 6ot3
  • View 6ot3
Molmil generated image of 6ot3
RF2 ACCOMMODATED STATE BOUND RELEASE COMPLEX 70S AT 24 MS
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-02
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
6OUO
  • Download 6ouo
  • View 6ouo
Molmil generated image of 6ouo
RF2 ACCOMMODATED STATE BOUND 70S COMPLEX AT LONG INCUBATION TIME
Descriptor:23S ribosomal RNA, 16S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Fu, Z., Indrisiunaite, G., Kaledhonkar, S., Shah, B., Sun, M., Chen, B., Grassucci, R.A., Ehrenberg, M., Frank, J.
Deposit date:2019-05-05
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
1SIQ
  • Download 1siq
  • View 1siq
Molmil generated image of 1siq
THE CRYSTAL STRUCTURE AND MECHANISM OF HUMAN GLUTARYL-COA DEHYDROGENASE
Descriptor:Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Wang, M., Fu, Z., Paschke, R., Goodman, S., Frerman, F.E., Kim, J.J.
Deposit date:2004-03-01
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions
Biochemistry, 43, 2004
1SIR
  • Download 1sir
  • View 1sir
Molmil generated image of 1sir
THE CRYSTAL STRUCTURE AND MECHANISM OF HUMAN GLUTARYL-COA DEHYDROGENASE
Descriptor:Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, S-4-NITROBUTYRYL-COA
Authors:Wang, M., Fu, Z., Paschke, R., Goodman, S.L., Frerman, F.E., Kim, J.J.
Deposit date:2004-03-01
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions
Biochemistry, 43, 2004
3N7J
  • Download 3n7j
  • View 3n7j
Molmil generated image of 3n7j
CRYSTAL STRUCTURE OF BOTULINUM NEUROTOXIN SEROTYPE D BINDING DOMAIN
Descriptor:Botulinum neurotoxin type D
Authors:Fu, Z., Baldwin, M.R., Karalewitz, A., Kroken, A., Barbieri, J.T., Kim, J.-J.P.
Deposit date:2010-05-27
Release date:2010-09-08
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .
Biochemistry, 49, 2010
<123>