Author results

5HA9
  • Download 5ha9
  • View 5ha9
Molmil generated image of 5ha9
CRYSTAL STRUCTURE-BASED DESIGN AND DISOVERY OF A NOVEL PARP1 ANTIAGONIST (BL-PA10) THAT INDUCES APOPTOSIS AND INHIBITS METASTASIS IN TRIPLE NEGATIVE BREAST CANCER
Descriptor:Poly [ADP-ribose] polymerase 1, GLYCEROL, SULFATE ION, ...
Authors:Fu, L., Peng, H., Zhang, L., Ouyang, L.
Deposit date:2015-12-30
Release date:2016-03-09
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (4.01 Å)
Cite:Crystal structure-based discovery of a novel synthesized PARP1 inhibitor (OL-1) with apoptosis-inducing mechanisms in triple-negative breast cancer.
Sci Rep, 6, 2016
5JYY
  • Download 5jyy
  • View 5jyy
Molmil generated image of 5jyy
STRUCTURE-BASED TETRAVALENT ZANAMIVIR WITH POTENT INHIBITORY ACTIVITY AGAINST DRUG-RESISTANT INFLUENZA VIRUSES
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Fu, L., Wu, Y., Bi, Y., Zhang, S., Lv, X., Qi, J., Li, Y., Lu, X., Yan, J., Gao, G.F., Li, X.
Deposit date:2016-05-15
Release date:2016-06-29
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
J.Med.Chem., 59, 2016
5H4D
  • Download 5h4d
  • View 5h4d
Molmil generated image of 5h4d
CRYSTAL STRUCTURE OF HSIRT3 IN COMPLEX WITH A SPECIFIC AGONIST AMIODARONE HYDROCHLORIDE
Descriptor:NAD-dependent protein deacetylase sirtuin-3, mitochondrial, ARG-HIS-LYS, ...
Authors:Zhang, S., Fu, L., Liu, J., Liu, B.
Deposit date:2016-10-31
Release date:2017-11-08
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Crystal structure of hSIRT3 in complex with a specific agonist Amiodarone hydrochloride
To Be Published
4KMA
  • Download 4kma
  • View 4kma
Molmil generated image of 4kma
CRYSTAL STRUCTURE OF DROSOPHILA SUPPRESSOR OF FUSED
Descriptor:GM14141p
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
4L72
  • Download 4l72
  • View 4l72
Molmil generated image of 4l72
CRYSTAL STRUCTURE OF MERS-COV COMPLEXED WITH HUMAN DPP4
Descriptor:Dipeptidyl peptidase 4, MERS-CoV RBD, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Wang, X.Q., Wang, N.S.
Deposit date:2013-06-13
Release date:2013-08-21
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (3.005 Å)
Cite:Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4
Cell Res., 23, 2013
4ZS6
  • Download 4zs6
  • View 4zs6
Molmil generated image of 4zs6
RECEPTOR BINDING DOMAIN AND FAB COMPLEX
Descriptor:fab Light Chain, fab Heavy Chain, S protein, ...
Authors:Yu, X., Wang, X.
Deposit date:2015-05-13
Release date:2015-09-02
Method:X-RAY DIFFRACTION (3.166 Å)
Cite:Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27
Sci Rep, 5, 2015
4KM8
  • Download 4km8
  • View 4km8
Molmil generated image of 4km8
CRYSTAL STRUCTURE OF SUFUD60
Descriptor:Suppressor of fused homolog
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
4KM9
  • Download 4km9
  • View 4km9
Molmil generated image of 4km9
CRYSTAL STRUCTURE OF HUMAN SUPPRESSOR OF FUSED
Descriptor:Suppressor of fused homolog
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
4KMD
  • Download 4kmd
  • View 4kmd
Molmil generated image of 4kmd
CRYSTAL STRUCTURE OF SUFUD60-GLI1P
Descriptor:Sufu, Zinc finger protein GLI1, GLYCEROL, ...
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
4KMH
  • Download 4kmh
  • View 4kmh
Molmil generated image of 4kmh
CRYSTAL STRUCTURE OF SUPPRESSOR OF FUSED D20
Descriptor:Suppressor of fused homolog
Authors:Zhang, Y., Qi, X., Zhang, Z., Wu, G.
Deposit date:2013-05-08
Release date:2013-11-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
5W21
  • Download 5w21
  • View 5w21
Molmil generated image of 5w21
CRYSTAL STRUCTURE OF A 1:1:1 FGF23-FGFR1C-AKLOTHO TERNARY COMPLEX
Descriptor:Klotho, Fibroblast growth factor 23, Fibroblast growth factor receptor 1, ...
Authors:Mohammadi, M.
Deposit date:2017-06-05
Release date:2018-01-24
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:alpha-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.
Nature, 553, 2018