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7R7P
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BU of 7r7p by Molmil
Immature HIV-1 CACTD-SP1 lattice with Bevirimat (BVM) and Inositol hexakisphosphate (IP6)
Descriptor: 3alpha-[(3-carboxy-3-methylbutanoyl)oxy]-8alpha,9beta,10alpha,13alpha,17alpha,19beta-lup-20(29)-en-28-oic acid, Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
Authors:Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T.
Deposit date:2021-06-25
Release date:2023-02-15
Last modified:2023-03-22
Method:SOLID-STATE NMR
Cite:Structural basis of HIV-1 maturation inhibitor binding and activity.
Nat Commun, 14, 2023
7R7Q
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BU of 7r7q by Molmil
Immature HIV-1 CACTD-SP1 lattice with Inositol hexakisphosphate (IP6)
Descriptor: Gag polyprotein, INOSITOL HEXAKISPHOSPHATE
Authors:Sarkar, S, Zadrozny, K.K, Zadorozhnyi, R, Russell, R.W, Quinn, C.M, Kleinpeter, A, Ablan, S, Meshkin, H, Perilla, J.R, Ganser-Pornillos, B.K, Pornillos, O, Freed, E.O, Gronenborn, A.M, Polenova, T.
Deposit date:2021-06-25
Release date:2023-02-15
Last modified:2023-03-22
Method:SOLID-STATE NMR
Cite:Structural basis of HIV-1 maturation inhibitor binding and activity.
Nat Commun, 14, 2023
2N1R
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BU of 2n1r by Molmil
NMR Structure of the Myristylated Feline Immunodeficiency Virus Matrix Protein
Descriptor: Matrix protein p15
Authors:Brown, L.A, Cox, C, Button, R.J, Baptiste, J, Bahlow, K, Spurrier, V, Luttge, B.G, Kuo, L, Freed, E.O, Summers, M.F, Kyser, J, Summers, H.R.
Deposit date:2015-04-15
Release date:2015-05-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR structure of the myristylated feline immunodeficiency virus matrix protein.
Viruses, 7, 2015
2NV3
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BU of 2nv3 by Molmil
Solution structure of L8A mutant of HIV-1 myristoylated matrix protein
Descriptor: Gag polyprotein, MYRISTIC ACID
Authors:Saad, J.S, Loeliger, E, Luncsford, P, Liriano, M, Tai, J, Kim, A, Miller, J, Joshi, A, Freed, E.O, Summers, M.F.
Deposit date:2006-11-10
Release date:2007-02-06
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Point mutations in the HIV-1 matrix protein turn off the myristyl switch.
J.Mol.Biol., 366, 2007
2K4H
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BU of 2k4h by Molmil
Solution structure of the HIV-2 myristoylated Matrix protein
Descriptor: HIV-2 myristoylated matrix protein, MYRISTIC ACID
Authors:Saad, J.S, Ablan, S.D, Ghanam, R.H, Kim, A, Andrews, K, Nagashima, K, Freed, E.O, Summers, M.F.
Deposit date:2008-06-08
Release date:2008-08-12
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.
J.Mol.Biol., 382, 2008
2K4I
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BU of 2k4i by Molmil
Solution structure of HIV-2 myrMA bound to di-C4-PI(4,5)P2
Descriptor: (2R)-3-{[(R)-HYDROXY{[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIHYDROXY-4,5-BIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}PHOSPHORYL]OXY}PROPANE-1,2-DIYL DIBUTANOATE, HIV-2 myristoylated matrix protein, MYRISTIC ACID
Authors:Saad, J.S, Ablan, S.D, Ghanam, R.H, Kim, A, Andrews, K, Nagashima, K, Freed, E.O, Summers, M.F.
Deposit date:2008-06-08
Release date:2008-08-12
Last modified:2014-01-29
Method:SOLUTION NMR
Cite:Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.
J.Mol.Biol., 382, 2008
2K4E
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BU of 2k4e by Molmil
Solution structure of the HIV-2 UNMYRISTOYLATED MATRIX PROTEIN
Descriptor: HIV-2 unmyristoylated matrix protein
Authors:Saad, J.S, Ablan, S.D, Ghanam, R.H, Kim, A, Andrews, K, Nagashima, K, Freed, E.O, Summers, M.F.
Deposit date:2008-06-07
Release date:2008-08-12
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting.
J.Mol.Biol., 382, 2008
2JMG
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BU of 2jmg by Molmil
Solution structure of V7R mutant of HIV-1 myristoylated matrix protein
Descriptor: Gag polyprotein, MYRISTIC ACID
Authors:Saad, J.S, Loeliger, E, Luncsford, P, Liriano, M, Tai, J, Kim, A, Miller, J, Joshi, A, Freed, E.O, Summers, M.F.
Deposit date:2006-11-11
Release date:2007-02-06
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:Point mutations in the HIV-1 matrix protein turn off the myristyl switch.
J.Mol.Biol., 366, 2007
6WA4
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BU of 6wa4 by Molmil
Solution NMR structure of the unmyristoylated feline immunodeficiency virus matrix protein
Descriptor: Matrix protein
Authors:Brown, J.B, Summers, H.R, Brown, L.A, Marchant, J, Canova, P.N, O'Hern, C.T, Abbott, S.T, Nyaunu, C, Maxwell, S, Johnson, T, Moser, M.B, Carter, H, Ablan, S, Freed, E.O, Summers, M.F.
Deposit date:2020-03-24
Release date:2020-07-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus.
J.Mol.Biol., 432, 2020
6WA3
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BU of 6wa3 by Molmil
Solution NMR structure of the myristoylated feline immunodeficiency virus matrix protein
Descriptor: MYRISTIC ACID, Matrix protein
Authors:Brown, J.B, Summers, H.R, Brown, L.A, Marchant, J, Canova, P.N, O'Hern, C.T, Abbott, S, Nyaunu, C, Maxwell, S, Johnson, T, Moser, M, Ablan, S.D, Carter, H, Freed, E.O, Summers, M.F.
Deposit date:2020-03-24
Release date:2020-07-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus.
J.Mol.Biol., 432, 2020
6WA5
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BU of 6wa5 by Molmil
Solution NMR Structure of the G4L/Q5K/G6S (NOS) Unmyristoylated Feline Immunodeficiency Virus Matrix Protein
Descriptor: Matrix protein
Authors:Brown, J.B, Summers, H.R, Brown, L.A, Marchant, J, Canova, P.N, O'Hern, C.T, Abbott, S.T, Nyaunu, C, Maxwell, S, Johnson, T, Moser, M.B, Ablan, S.A, Carter, H, Freed, E.O, Summers, M.F.
Deposit date:2020-03-24
Release date:2020-07-22
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and Mechanistic Studies of the Rare Myristoylation Signal of the Feline Immunodeficiency Virus.
J.Mol.Biol., 432, 2020
7ASL
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BU of 7asl by Molmil
HIV-1 Gag immature lattice. GagSP1T8I
Descriptor: Gag protein
Authors:Mendonca, L, Zhang, P.
Deposit date:2020-10-27
Release date:2021-06-23
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:CryoET structures of immature HIV Gag reveal six-helix bundle.
Commun Biol, 4, 2021
7ASH
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BU of 7ash by Molmil
HIV-1 Gag immature lattice. GagdeltaMASP1T8I
Descriptor: Gag protein
Authors:Mendonca, L, Zhang, P.
Deposit date:2020-10-27
Release date:2021-06-23
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:CryoET structures of immature HIV Gag reveal six-helix bundle.
Commun Biol, 4, 2021
2OJQ
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BU of 2ojq by Molmil
Crystal structure of Alix V domain
Descriptor: Programmed cell death 6-interacting protein
Authors:Lee, S, Hurley, J.H.
Deposit date:2007-01-13
Release date:2007-02-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural basis for viral late-domain binding to Alix
Nat.Struct.Mol.Biol., 14, 2007
5UP4
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BU of 5up4 by Molmil
Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM
Descriptor: HIV-1 Capsid Protein and spacer peptide 1
Authors:Perilla, J.R, Schirra, R, Zhang, P, Schulten, K.
Deposit date:2017-02-01
Release date:2017-12-06
Last modified:2017-12-13
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Quenching protein dynamics interferes with HIV capsid maturation.
Nat Commun, 8, 2017
3OBU
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BU of 3obu by Molmil
Crystal structure of the Tsg101 UEV domain in complex with a HIV-1 PTAP peptide
Descriptor: Gag polyprotein, Tumor susceptibility gene 101 protein
Authors:Im, Y.J, Hurley, J.H.
Deposit date:2010-08-09
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction.
Structure, 18, 2010
3OBQ
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BU of 3obq by Molmil
Crystal Structure of the Tsg101 UEV domain in complex with a human HRS PSAP peptide
Descriptor: Hepatocyte growth factor-regulated tyrosine kinase substrate, Tumor susceptibility gene 101 protein
Authors:Im, Y.J, Hurley, J.H.
Deposit date:2010-08-09
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction.
Structure, 18, 2010
3OBX
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BU of 3obx by Molmil
Crystal structure of the Tsg101 UEV domain in complex with a HIV-1 Gag P7A mutant peptide
Descriptor: Gag polyprotein, Tumor susceptibility gene 101 protein
Authors:Im, Y.J, Hurley, J.H.
Deposit date:2010-08-09
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction.
Structure, 18, 2010
3OBS
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BU of 3obs by Molmil
Crystal structure of Tsg101 UEV domain
Descriptor: Tumor susceptibility gene 101 protein
Authors:Im, Y.J, Hurley, J.H.
Deposit date:2010-08-09
Release date:2010-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystallographic and Functional Analysis of the ESCRT-I /HIV-1 Gag PTAP Interaction.
Structure, 18, 2010
3P9G
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BU of 3p9g by Molmil
Crystal structure of the TSG101 UEV domain in complex with FA459 peptide
Descriptor: Gag polyprotein, Tumor susceptibility gene 101 protein
Authors:Hurley, J.H, Im, Y.J.
Deposit date:2010-10-17
Release date:2011-06-29
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Elucidation of New Binding Interactions with the Tumor Susceptibility Gene 101 (Tsg101) Protein Using Modified HIV-1 Gag-p6 Derived Peptide Ligands.
ACS Med Chem Lett, 2, 2011
3P9H
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BU of 3p9h by Molmil
Crystal structure of the TSG101 UEV domain in complex with FA258 peptide
Descriptor: Gag polyprotein, Tumor susceptibility gene 101 protein
Authors:Hurley, J.H, Im, Y.J.
Deposit date:2010-10-17
Release date:2011-06-29
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Elucidation of New Binding Interactions with the Tumor Susceptibility Gene 101 (Tsg101) Protein Using Modified HIV-1 Gag-p6 Derived Peptide Ligands.
ACS Med Chem Lett, 2, 2011
6AXT
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BU of 6axt by Molmil
Structure of the T58S/T107I/P122A mutant of the HIV-1 capsid protein
Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-09-07
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6AXY
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BU of 6axy by Molmil
Structure of the V11I/T58A/I124A mutant of the HIV-1 capsid protein
Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-09-07
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published
6AXW
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BU of 6axw by Molmil
Structure of the I124A mutant of the HIV-1 capsid protein
Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-09-07
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation.
MBio, 9, 2018
6AXS
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BU of 6axs by Molmil
Structure of the V11I/T58A/P122A mutant of the HIV-1 capsid protein
Descriptor: CHLORIDE ION, HIV-1 capsid protein, IODIDE ION
Authors:Gres, A.T, Kirby, K.A, Sarafianos, S.G.
Deposit date:2017-09-07
Release date:2018-09-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Identification of a novel element in HIV-1 capsid critical for assembly and maturation
To be published

 

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