Author results

1JLI
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HUMAN INTERLEUKIN 3 (IL-3) MUTANT WITH TRUNCATION AT BOTH N-AND C-TERMINI AND 14 RESIDUE CHANGES, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:INTERLEUKIN 3
Authors:Feng, Y., Klein, B.K., Mcwherter, C.A.
Deposit date:1995-12-14
Release date:1997-06-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional solution structure and backbone dynamics of a variant of human interleukin-3.
J.Mol.Biol., 259, 1996
2LEO
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SOLUTION STRUCTURE OF ESOPHAGEAL CANCER-RELATED GENE 2
Descriptor:Serine protease inhibitor Kazal-type 7
Authors:Feng, Y., Geng, Y., Wang, J.
Deposit date:2011-06-20
Release date:2012-05-30
Method:SOLUTION NMR
Cite:NMR structure note: human esophageal cancer-related gene 2
J.Biomol.Nmr, 53, 2012
5I2D
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CRYSTAL STRUCTURE OF T. THERMOPHILUS TTHB099 CLASS II TRANSCRIPTION ACTIVATION COMPLEX: TAP-RPO
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Zhang, Y., Ebright, R.H.
Deposit date:2016-02-08
Release date:2016-06-22
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (4.405 Å)
Cite:Structural basis of transcription activation.
Science, 352, 2016
4ZH2
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH CBR703
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Ebright, R.H.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (4.204 Å)
Cite:Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
4ZH3
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH CBRH16-BR
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Ebright, R.H.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (4.082 Å)
Cite:Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
4ZH4
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH CBRP18
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Ebright, R.H.
Deposit date:2015-04-24
Release date:2015-08-05
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (3.993 Å)
Cite:Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles.
Structure, 23, 2015
1HOV
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SOLUTION STRUCTURE OF A CATALYTIC DOMAIN OF MMP-2 COMPLEXED WITH SC-74020
Descriptor:MATRIX METALLOPROTEINASE-2, ZINC ION, CALCIUM ION, ...
Authors:Feng, Y., Likos, J.J., Zhu, L., Woodward, H., Munie, G., McDonald, J.J., Stevens, A.M., Howard, C.P., De Crescenzo, G.A., Welsch, D., Shieh, H.-S., Stallings, W.C.
Deposit date:2000-12-11
Release date:2001-12-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor
Biochim.Biophys.Acta, 1598, 2002
1Z7P
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SOLUTION STRUCTURE OF REDUCED GLUTAREDOXIN C1 FROM POPULUS TREMULA X TREMULOIDES
Descriptor:glutaredoxin
Authors:Feng, Y., Zhong, N., Rouhier, N., Jacquot, J.P., Xia, B.
Deposit date:2005-03-26
Release date:2006-03-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Insight into Poplar Glutaredoxin C1 with a Bridging Iron-Sulfur Cluster at the Active Site
Biochemistry, 45, 2006
1Z7R
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SOLUTION STRUCTURE OF REDUCED GLUTAREDOXIN C1 FROM POPULUS TREMULA X TREMULOIDES
Descriptor:glutaredoxin
Authors:Feng, Y., Zhong, N., Rouhier, N., Jacquot, J.P., Xia, B.
Deposit date:2005-03-26
Release date:2006-03-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Insight into Poplar Glutaredoxin C1 with a Bridging Iron-Sulfur Cluster at the Active Site
Biochemistry, 45, 2006
2HR9
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SOLUTION STRUCTURE OF HUMAN TRANSLATIONALLY CONTROLLED TUMOR PROTEIN
Descriptor:Translationally-controlled tumor protein
Authors:Feng, Y., Liu, D., Yao, H., Wang, J.
Deposit date:2006-07-20
Release date:2006-08-08
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and mapping of a very weak calcium-binding site of human translationally controlled tumor protein by NMR
Arch.Biochem.Biophys., 48, 2007
2KJG
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SOLUTION STRUCTURE OF AN ARCHAEAL PROTEIN SSO6904 FROM HYPERTHERMOPHILIC SULFOLOBUS SOLFATARICUS
Descriptor:Archaeal protein SSO6904
Authors:Feng, Y., Yao, H., Wang, J.
Deposit date:2009-05-28
Release date:2009-10-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and calcium binding of protein SSO6904 from the hyperthermophilic archaeon Sulfolobus solfataricus.
Proteins, 78, 2009
2MMP
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SOLUTION STRUCTURE OF A RIBOSOMAL PROTEIN
Descriptor:Uncharacterized protein
Authors:Feng, Y.
Deposit date:2014-03-17
Release date:2014-06-11
Method:SOLUTION NMR
Cite:Structure determination of archaea-specific ribosomal protein L46a reveals a novel protein fold
Biochem.Biophys.Res.Commun., 2014
3CVA
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HUMAN BCL-XL CONTAINING A TRP TO ALA MUTATION AT POSITION 137
Descriptor:Apoptosis regulator Bcl-X
Authors:Feng, Y., Zhang, L., Hu, T., Shen, X., Chen, K., Jiang, H., Liu, D.
Deposit date:2008-04-18
Release date:2009-03-24
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A conserved hydrophobic core at Bcl-x(L) mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein
Arch.Biochem.Biophys., 484, 2009
3KXT
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CRYSTAL STRUCTURE OF SULFOLOBUS CREN7-DSDNA COMPLEX
Descriptor:Chromatin protein Cren7, 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3'
Authors:Feng, Y., Wang, J.
Deposit date:2009-12-03
Release date:2010-06-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Crystal structure of the crenarchaeal conserved chromatin protein Cren7 and double-stranded DNA complex
Protein Sci., 19, 2010
5H9U
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CRYSTAL STRUCTURE OF A THERMOSTABLE METHIONINE ADENOSYLTRANSFERASE
Descriptor:S-adenosylmethionine synthase
Authors:Feng, Y., Wang, W.
Deposit date:2015-12-29
Release date:2017-01-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.667 Å)
Cite:Crystal structure of a thermostable methionine adenosyltransferase
To Be Published
4R5Y
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THE COMPLEX STRUCTURE OF BRAF V600E KINASE DOMAIN WITH A NOVEL BRAF INHIBITOR
Descriptor:Serine/threonine-protein kinase B-raf, 5-({(1R,1aS,6bR)-1-[5-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl}oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
Authors:Feng, Y., Peng, H., Zhang, Y., Liu, Y., Wei, M.
Deposit date:2014-08-22
Release date:2016-02-24
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers.
Mol.Cancer Ther., 14, 2015
1APC
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SOLUTION STRUCTURE OF APOCYTOCHROME B562
Descriptor:CYTOCHROME B562
Authors:Wand, A.J., Feng, Y., Sligar, S.G.
Deposit date:1993-10-14
Release date:1994-01-31
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of apocytochrome b562.
Nat.Struct.Biol., 1, 1994
5YIJ
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STRUCTURE OF A LEGIONELLA EFFECTOR WITH SUBSTRATES
Descriptor:SdeA, Ubiquitin, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
Authors:Feng, Y., Mu, Y., Wang, H.
Deposit date:2017-10-05
Release date:2018-05-30
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
5YIK
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STRUCTURE OF A LEGIONELLA EFFECTOR WITH ITS SUBSTRATE
Descriptor:SdeA, ubiquitin
Authors:Feng, Y., Dong, Y., Liu, Z.
Deposit date:2017-10-05
Release date:2018-05-30
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (3.102 Å)
Cite:Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
5YIM
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STRUCTURE OF A LEGIONELLA EFFECTOR
Descriptor:SdeA
Authors:Feng, Y., Dong, Y., Wang, W.
Deposit date:2017-10-05
Release date:2018-05-30
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (3.394 Å)
Cite:Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
4JND
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STRUCTURE OF A C.ELEGANS SEX DETERMINING PROTEIN
Descriptor:Ca(2+)/calmodulin-dependent protein kinase phosphatase, MAGNESIUM ION
Authors:Feng, Y., Zhang, Y., Ge, J., Yang, M.
Deposit date:2013-03-15
Release date:2013-06-19
Last modified:2015-06-17
Method:X-RAY DIFFRACTION (1.652 Å)
Cite:Structural insight into Caenorhabditis elegans sex-determining protein FEM-2.
J.Biol.Chem., 288, 2013
5GTB
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CRYSTAL STRUCTURE OF INTERMEMBRANE SPACE REGION OF THE ARC6-PDV2 COMPLEX
Descriptor:Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, chloroplastic, Plastid division protein PDV2
Authors:Feng, Y., Wang, W.
Deposit date:2016-08-19
Release date:2017-03-01
Last modified:2017-03-15
Method:X-RAY DIFFRACTION (2.871 Å)
Cite:Structural insights into the coordination of plastid division by the ARC6-PDV2 complex
Nat Plants, 3, 2017
5HAD
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CRYSTAL STRUCTURE OF INTERMEMBRANE SPACE REGION OF CHLOROPLAST PROTEIN ARC6
Descriptor:Protein ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6, chloroplastic, 1,2-ETHANEDIOL
Authors:Feng, Y., Yu, X.
Deposit date:2015-12-30
Release date:2017-01-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.238 Å)
Cite:Structural insights into the coordination of plastid division by the ARC6-PDV2 complex
Nat Plants, 3, 2017
4MEX
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE IN COMPLEX WITH SALINAMIDE A
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Zhang, Y., Arnold, E., Ebright, R.H.
Deposit date:2013-08-27
Release date:2014-05-21
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3.902 Å)
Cite:Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
4MEY
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CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNA POLYMERASE HOLOENZYME
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Feng, Y., Zhang, Y., Arnold, E., Ebright, R.H.
Deposit date:2013-08-27
Release date:2014-05-21
Last modified:2014-06-25
Method:X-RAY DIFFRACTION (3.948 Å)
Cite:Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014