Author results

2Z5F
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HUMAN SULFOTRANSFERASE SULT1B1 IN COMPLEX WITH PAP
Descriptor:Sulfotransferase family cytosolic 1B member 1, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Dombrovski, L., Pegasova, T., Wu, H., Loppnau, P., Edwards, A.M., Arrowsmith, C.H., Sundstrom, M., Plotnikov, A.N., Bochkarev, A., Structural Genomics Consortium (SGC)
Deposit date:2007-07-07
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of human sulfotransferases SULT1B1 and SULT1C1 complexed with the cofactor product adenosine-3'-5'-diphosphate (PAP)
Proteins, 64, 2006
3HM5
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SANT DOMAIN OF HUMAN DNA METHYLTRANSFERASE 1 ASSOCIATED PROTEIN 1
Descriptor:DNA methyltransferase 1-associated protein 1, CALCIUM ION, UNKNOWN ATOM OR ION
Authors:Dombrovski, L., Tempel, W., Amaya, M.F., Tong, Y., Ni, S., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Park, H., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2009-05-28
Release date:2009-06-16
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SANT domain of human DNA methyltransferase 1 associated protein 1
To be Published
2F2S
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HUMAN MITOCHONDRIAL ACETOACETYL-COA THIOLASE
Descriptor:Acetyl-CoA acetyltransferase, mitochondrial, CHLORIDE ION, ...
Authors:Min, J.R., Dombrovski, L., Antoshenko, T., Wu, H., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2005-11-17
Release date:2005-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human Mitochondrial Acetoacetyl-Coa Thiolase Acat1.
To be Published
3BFX
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CRYSTAL STRUCTURE OF HUMAN SULFOTRANSFERASE SULT1C1 IN COMPLEX WITH PAP
Descriptor:Sulfotransferase 1C2, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Dong, A., Dombrovski, L., Loppnau, P., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2007-11-23
Release date:2007-12-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Human Sulfotransferases Sult1B1 and Sult1C1 Complexed with the Cofactor Product Adenosine-3'-5'-Diphosphate (Pap).
Proteins, 64, 2006
3DLM
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CRYSTAL STRUCTURE OF TUDOR DOMAIN OF HUMAN HISTONE-LYSINE N-METHYLTRANSFERASE SETDB1
Descriptor:Histone-lysine N-methyltransferase SETDB1
Authors:Amaya, M.F., Dombrovski, L., Loppnau, P., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2008-06-27
Release date:2008-08-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:The crystal structure of Tudor domain of human Histone-lysine N-methyltransferase SETDB1.
To be Published
3F2K
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STRUCTURE OF THE TRANSPOSASE DOMAIN OF HUMAN HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR
Descriptor:Histone-lysine N-methyltransferase SETMAR, LYFA Peptide, MAGNESIUM ION
Authors:Amaya, M.F., Dombrovski, L., Ni, S., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Botchkarev, A., Min, J., Plotnikov, A.N., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2008-10-29
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Crystal Structure of Transposase Domain of Human Histone-lysine N-methyltransferase SETMAR.
To be Published
3QWP
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CRYSTAL STRUCTURE OF SET AND MYND DOMAIN CONTAINING 3; ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 1
Descriptor:SET and MYND domain-containing protein 3, ZINC ION, S-ADENOSYLMETHIONINE, ...
Authors:Dong, A., Dombrovski, L., Li, Y., Wernimont, A., Weigelt, J., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2011-02-28
Release date:2011-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:The Crystal Structure of human Histone-lysine N-methyltransferase SMYD3
To be Published
4IJD
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CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAIN OF HUMAN PR DOMAIN-CONTAINING PROTEIN 9
Descriptor:Histone-lysine N-methyltransferase PRDM9, ZINC ION, UNKNOWN ATOM OR ION
Authors:Dong, A., Dombrovski, L., Li, Y., Tempel, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2012-12-21
Release date:2013-02-13
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of methyltransferase domain of human PR domain-containing protein 9
To be Published
4IKP
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CRYSTAL STRUCTURE OF COACTIVATOR-ASSOCIATED ARGININE METHYLTRANSFERASE 1 WITH METHYLENESINEFUNGIN
Descriptor:Histone-arginine methyltransferase CARM1, (2S,5S)-2,6-diamino-5-{[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}hexanoic acid, GLYCEROL, ...
Authors:Dong, A., Dombrovski, L., He, H., Ibanez, G., Wernimont, A., Zheng, W., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Min, J., Luo, M., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2012-12-27
Release date:2013-02-13
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of coactivator-associated arginine methyltransferase 1 with methylenesinefungin
TO BE PUBLISHED
4LD6
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PWWP DOMAIN OF HUMAN PWWP DOMAIN-CONTAINING PROTEIN 2B
Descriptor:PWWP domain-containing protein 2B, GLYCEROL, UNKNOWN ATOM OR ION
Authors:Dong, A., Dombrovski, L., Tempel, W., Loppnau, P., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2013-06-24
Release date:2013-07-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of PWWP domain of human PWWP Domain-Containing Protein 2B
To be Published
4QQE
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CRYSTAL STRUCTURE OF WDR5, WD REPEAT DOMAIN 5 IN COMPLEX WITH COMPOUND SGC-DS-MT-0345
Descriptor:WD repeat-containing protein 5, N-[2-(4-methylpiperazin-1-yl)-5-(quinolin-3-yl)phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide, CHLORIDE ION, ...
Authors:Dong, A., Dombrovski, L., Wernimont, A., Smil, D., Getlik, M., Senisterra, G., Poda, G., Al-Awar, R., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Brown, P.J., Schapira, M., Vedadi, M., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2014-06-27
Release date:2014-07-30
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of WDR5, WD repeat domain 5 in complex with compound SGC-DS-MT-0345
To be Published
5EAL
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CRYSTAL STRUCTURE OF HUMAN WDR5 IN COMPLEX WITH COMPOUND 9H
Descriptor:WD repeat-containing protein 5, 3-methyl-~{N}-[2-(4-methylpiperazin-1-yl)-5-quinolin-3-yl-phenyl]benzamide, GLYCEROL, ...
Authors:DONG, A., DOMBROVSKI, L., SMIL, D., GETLIK, M., BOLSHAN, Y., WALKER, J.R., SENISTERRA, G., PODA, G., AL-AWAR, R., SCHAPIRA, M., VEDADI, M., Bountra, C., Edwards, A.M., Arrowsmith, C.H., BROWN, P.J., WU, H., Structural Genomics Consortium (SGC)
Deposit date:2015-10-16
Release date:2015-11-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of human WDR5 in complex with compound 9h
to be published
1ZD1
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HUMAN SULFORTRANSFERASE SULT4A1
Descriptor:Sulfotransferase 4A1, GLYCEROL
Authors:Dong, A., Dombrovski, L., Loppnau, P., Edwards, A.M., Arrowsmith, C.H., Sundstrom, M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structural and chemical profiling of the human cytosolic sulfotransferases.
Plos Biol., 5, 2007
1ZRH
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CRYSTAL STRUCTURE OF HUMAN HEPARAN SULFATE GLUCOSAMINE 3-O-SULFOTRANSFERASE 1 IN COMPLEX WITH PAP
Descriptor:Heparan sulfate glucosamine 3-O-sulfotransferase 1, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Dong, A., Dombrovski, L., Loppnau, P., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2005-05-19
Release date:2005-06-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Human heparan sulfate glucosamine 3-O-sulfotransferase 1 in complex with PAP
To be Published
2AD1
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HUMAN SULFOTRANSFERASE SULT1C2
Descriptor:Sulfotransferase 1C2
Authors:Dong, A., Dombrovski, L., Loppnau, P., Edwards, A.M., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2005-07-19
Release date:2005-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and chemical profiling of the human cytosolic sulfotransferases.
Plos Biol., 5, 2007
2GWH
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HUMAN SULFOTRANFERASE SULT1C2 IN COMPLEX WITH PAP AND PENTACHLOROPHENOL
Descriptor:Sulfotransferase 1C2, ADENOSINE-3'-5'-DIPHOSPHATE, PENTACHLOROPHENOL, ...
Authors:Tempel, W., Pan, P.W., Dombrovski, L., Allali-Hassani, A., Vedadi, M., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2006-05-04
Release date:2006-05-16
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and chemical profiling of the human cytosolic sulfotransferases.
Plos Biol., 5, 2007
2H8K
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HUMAN SULFOTRANFERASE SULT1C3 IN COMPLEX WITH PAP
Descriptor:SULT1C3 splice variant d, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Tempel, W., Dombrovski, L., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2006-06-07
Release date:2006-06-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and chemical profiling of the human cytosolic sulfotransferases.
Plos Biol., 5, 2007
2IJA
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HUMAN N-ACETYLTRANSFERASE 1 F125S MUTANT
Descriptor:Arylamine N-acetyltransferase 1, SODIUM ION, ACETAMIDE, ...
Authors:Tempel, W., Wu, H., Dombrovski, L., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Grant, D.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2006-09-29
Release date:2006-11-28
Last modified:2018-06-06
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:The Crystal Structure of Human N-acetyltransferase 1 mutant, F125S
To be Published
2OU2
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ACETYLTRANSFERASE DOMAIN OF HUMAN HIV-1 TAT INTERACTING PROTEIN, 60KDA, ISOFORM 3
Descriptor:Histone acetyltransferase HTATIP, ZINC ION, ACETYL COENZYME *A
Authors:Min, J., Wu, H., Dombrovski, L., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2007-02-09
Release date:2007-02-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The Crystal Structure of acetyltransferase domain of Human HIV-1 Tat interacting protein in complex with acetylcoenzyme A.
To be Published
2OZU
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CRYSTAL STRUCTURE OF HUMAN MYST HISTONE ACETYLTRANSFERASE 3 IN COMPLEX WITH ACETYLCOENZYME A
Descriptor:Histone acetyltransferase MYST3, ZINC ION, ACETYL COENZYME *A, ...
Authors:Min, J., Wu, H., Dombrovski, L., Bernstein, G., Dong, A., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2007-02-27
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structure of human MYST histone acetyltransferase 3 in complex with acetylcoenzyme A
To be Published
2PFR
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HUMAN N-ACETYLTRANSFERASE 2
Descriptor:Arylamine N-acetyltransferase 2, SULFATE ION, COENZYME A, ...
Authors:Tempel, W., Wu, H., Dombrovski, L., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Grant, D.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2007-04-05
Release date:2007-05-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:The Crystal Structure of Human N-acetyltransferase 2 in complex with CoA
to be published
2PQ8
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MYST HISTONE ACETYLTRANSFERASE 1
Descriptor:Probable histone acetyltransferase MYST1, ZINC ION, COENZYME A, ...
Authors:Tempel, W., Wu, H., Dombrovski, L., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2007-05-01
Release date:2007-05-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:MYST histone acetyltransferase 1.
To be Published
2QPW
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METHYLTRANSFERASE DOMAIN OF HUMAN PR DOMAIN-CONTAINING PROTEIN 2
Descriptor:PR domain zinc finger protein 2
Authors:Lunin, V.V., Wu, H., Dombrovski, L., Antoshenko, T., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2007-07-25
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
3DAX
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CRYSTAL STRUCTURE OF HUMAN CYP7A1
Descriptor:Cytochrome P450 7A1, PROTOPORPHYRIN IX CONTAINING FE, UNKNOWN ATOM OR ION
Authors:Strushkevich, N.V., Tempel, W., Dombrovski, L., Dong, A., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Wilkstrom, M., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
Deposit date:2008-05-30
Release date:2008-08-05
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of human CYP7A1
To be Published
3IHX
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METHYLTRANSFERASE DOMAIN OF HUMAN PR DOMAIN-CONTAINING PROTEIN 10
Descriptor:PR domain zinc finger protein 10
Authors:Amaya, M.F., Dombrovski, L., Ni, S., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Botchkarev, A., Min, J., Plotnikov, A.N., Wu, H., Structural Genomics Consortium (SGC)
Deposit date:2009-07-31
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Methyltransferase domain of human PR domain-containing protein 10
To be Published
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