3MEK

Crystal Structure of Human Histone-Lysine N-methyltransferase SMYD3 in Complex with S-adenosyl-L-methionine

Summary for 3MEK

• Entry DOI: 10.2210/pdb3mek/pdb
• Descriptor: SET and MYND domain-containing protein 3, ZINC ION, S-ADENOSYLMETHIONINE, ... (4 entities in total)
• Functional Keywords: histone methyltransferase, set and mynd domain-containing protein 3, zinc finger mynd domain-containing protein 1, histone h3, di-methylation, tri-methylation, transcriptional activation, dna-binding, mynd-type zinc finger, set domain, chromatin modification, alternative splicing, chromatin regulator, cytoplasm, metal-binding, methyltransferase, nucleus, s-adenosyl-l-methionine, transferase, zinc, zinc-finger, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : Q9H7B4
• Total number of polymer chains: 1
• Total formula weight: 50580.16

Authors

Lam, R.,Dombrovski, L.,Li, Y.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2010-03-31, release date: 2010-04-14, Last modification date: 2017-11-08)

• Primary citation: Lam, R.,Dombrovski, L.,Li, Y.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Wu, H.; Crystal Structure of Human Histone-Lysine N-methyltransferase SMYD3 in Complex with S-adenosyl-L-methionine; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)