4QQE

Crystal structure of WDR5, WD repeat domain 5 in complex with compound SGC-DS-MT-0345

Summary for 4QQE

• Entry DOI: 10.2210/pdb4qqe/pdb
• Descriptor: WD repeat-containing protein 5, N-[2-(4-methylpiperazin-1-yl)-5-(quinolin-3-yl)phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: wdr5, structural genomics, structural genomics consortium, sgc, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : P61964
• Total number of polymer chains: 1
• Total formula weight: 35019.05

Authors

Dong, A.,Dombrovski, L.,Wernimont, A.,Smil, D.,Getlik, M.,Senisterra, G.,Poda, G.,Al-Awar, R.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Schapira, M.,Vedadi, M.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2014-06-27, release date: 2014-07-30, Last modification date: 2023-09-20)

• Primary citation: Dombrovski, L.,Dong, A.,Wernimont, A.,Smil, D.,Getlik, M.,Senisterra, G.,Poda, G.,Al-Awar, R.,Bountra, C.,Arrowsmith, C.H.,Edwards, A.M.,Brown, P.J.,Schapira, M.,Vedadi, M.,Wu, H.; Crystal structure of WDR5, WD repeat domain 5 in complex with compound SGC-DS-MT-0345; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)