4QQE
Crystal structure of WDR5, WD repeat domain 5 in complex with compound SGC-DS-MT-0345
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | WD repeat-containing protein 5 | polymer | 312 | 34289.9 | 1 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (human) | BMP2-induced 3-kb gene protein |
| 2 | B (A) | N-[2-(4-methylpiperazin-1-yl)-5-(quinolin-3-yl)phenyl]-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide | non-polymer | 507.5 | 1 | Chemie (37F) | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D, E, F (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G, H, I, J, K... (A) | UNKNOWN ATOM OR ION | non-polymer | 7 | Chemie (UNX) | ||||
| 6 | N (A) | water | water | 18.0 | 217 | Chemie (HOH) |
Sequence modifications
A: 24 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34289.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 729.2 | |
| All* | Total formula weight | 35019.1 |
