5EAL
Crystal structure of human WDR5 in complex with compound 9h
Summary for 5EAL
Entry DOI | 10.2210/pdb5eal/pdb |
Related | 5EAM 5EAP 5EAR |
Descriptor | WD repeat-containing protein 5, 3-methyl-~{N}-[2-(4-methylpiperazin-1-yl)-5-quinolin-3-yl-phenyl]benzamide, GLYCEROL, ... (7 entities in total) |
Functional Keywords | wdr5, compound 9h, structural genomics, structural genomics consortium, sgc, transcription-transcription inhibitor complex, transcription/transcription inhibitor |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus : P61964 |
Total number of polymer chains | 2 |
Total formula weight | 70635.57 |
Authors | DONG, A.,DOMBROVSKI, L.,SMIL, D.,GETLIK, M.,BOLSHAN, Y.,WALKER, J.R.,SENISTERRA, G.,PODA, G.,AL-AWAR, R.,SCHAPIRA, M.,VEDADI, M.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,BROWN, P.J.,WU, H.,Structural Genomics Consortium (SGC) (deposition date: 2015-10-16, release date: 2015-11-04, Last modification date: 2023-09-27) |
Primary citation | DOMBROVSKI, L.,DONG, A.,SMIL, D.,GETLIK, M.,BOLSHAN, Y.,WALKER, J.R.,SENISTERRA, G.,PODA, G.,AL-AWAR, R.,SCHAPIRA, M.,VEDADI, M.,Bountra, C.,Edwards, A.M.,Arrowsmith, C.H.,BROWN, P.J.,WU, H.,Structural Genomics Consortium (SGC) Crystal structure of human WDR5 in complex with compound 9h to be published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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