5EAL
Crystal structure of human WDR5 in complex with compound 9h
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | WD repeat-containing protein 5 | polymer | 312 | 34289.9 | 2 | UniProt (P61964) Pfam (PF00400) In PDB | Homo sapiens (Human) | BMP2-induced 3-kb gene protein |
| 2 | B, A | 3-methyl-~{N}-[2-(4-methylpiperazin-1-yl)-5-quinolin-3-yl-phenyl]benzamide | non-polymer | 436.5 | 2 | Chemie (5ML) | |||
| 3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | B, A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 17 | Chemie (EDO) | |||
| 6 | B, A | UNKNOWN ATOM OR ION | non-polymer | 24 | Chemie (UNX) | ||||
| 7 | water | water | 18.0 | 481 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68579.8 | |
| Non-Polymers* | Number of molecules | 45 |
| Total formula weight | 2055.8 | |
| All* | Total formula weight | 70635.6 |
