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1KI1
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GUANINE NUCLEOTIDE EXCHANGE REGION OF INTERSECTIN IN COMPLEX WITH CDC42
Descriptor:G25K GTP-binding protein, placental isoform, intersectin long form, ...
Authors:Snyder, J.T., Pruitt, W.M., Der, C.J., Sondek, J.
Deposit date:2001-12-02
Release date:2002-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
1LB1
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CRYSTAL STRUCTURE OF THE DBL AND PLECKSTRIN HOMOLOGY DOMAINS OF DBS IN COMPLEX WITH RHOA
Descriptor:Guanine nucleotide exchange factor DBS, Transforming protein RhoA
Authors:Snyder, J.T., Worthylake, D.K., Rossman, K.L., Betts, L., Pruitt, W.M., Siderovski, D.P., Der, C.J., Sondek, J.
Deposit date:2002-04-01
Release date:2002-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
2PZ1
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CRYSTAL STRUCTURE OF AUTO-INHIBITED ASEF
Descriptor:Rho guanine nucleotide exchange factor 4
Authors:Betts, L., Sondek, J., Rossman, K.L.
Deposit date:2007-05-17
Release date:2007-08-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression.
Nat.Struct.Mol.Biol., 14, 2007
1WQ1
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RAS-RASGAP COMPLEX
Descriptor:H-RAS, P120GAP, MAGNESIUM ION, ...
Authors:Scheffzek, K., Ahmadian, M.R., Kabsch, W., Wiesmueller, L., Lautwein, A., Schmitz, F., Wittinghofer, A.
Deposit date:1997-07-03
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
Science, 277, 1997