Author results

6EHT
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MODULATION OF PCNA SLIDING SURFACE BY P15PAF SUGGESTS A SUPPRESSIVE MECHANISM FOR CISPLATIN-INDUCED DNA LESION BYPASS BY POL ETA HOLOENZYME
Descriptor:Proliferating cell nuclear antigen, PCNA-associated factor, DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), ...
Authors:De March, M., Barrera-Vilarmau, S., Mentegari, E., Merino, N., Bressan, E., Maga, G., Crehuet, R., Onesti, S., Blanco, F.J., De Biasio, A.
Deposit date:2017-09-15
Release date:2018-08-08
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
6GIS
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STRUCTURAL BASIS OF HUMAN CLAMP SLIDING ON DNA
Descriptor:Proliferating cell nuclear antigen, DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3')
Authors:De March, M., Merino, N., Barrera-Vilarmau, S., Crehuet, R., Onesti, S., Blanco, F.J., De Biasio, A.
Deposit date:2018-05-15
Release date:2018-05-30
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural basis of human PCNA sliding on DNA.
Nat Commun, 8, 2017
6GWS
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CRYSTAL STRUCTURE OF HUMAN PCNA IN COMPLEX WITH THREE P15 PEPTIDES
Descriptor:Proliferating cell nuclear antigen, PCNA-associated factor
Authors:De March, M., Merino, N., Gonzalez-Magana, A., Romano-Moreno, M., Onesti, S., Blanco, F.J., De Biasio, A.
Deposit date:2018-06-25
Release date:2018-08-22
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
3O1Y
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ELECTRON TRANSFER COMPLEXES: EXPERIMENTAL MAPPING OF THE REDOX-DEPENDENT CYTOCHROME C ELECTROSTATIC SURFACE
Descriptor:Cytochrome c, HEME C, NITRATE ION
Authors:De March, M., De Zorzi, R., Demitri, N., Gabbiani, C., Guerri, A., Casini, A., Messori, L., Geremia, S.
Deposit date:2010-07-22
Release date:2012-01-25
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Nitrate as a probe of cytochrome c surface: crystallographic identification of crucial "hot spots" for protein-protein recognition.
J. Inorg. Biochem., 135, 2014
3O20
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ELECTRON TRANSFER COMPLEXES:EXPERIMENTAL MAPPING OF THE REDOX-DEPENDENT CYTOCHROME C ELECTROSTATIC SURFACE
Descriptor:Cytochrome c, HEME C, NITRATE ION
Authors:De March, M., De Zorzi, R., Casini, A., Messori, L., Geremia, S., Demitri, N., Gabbiani, C., Guerri, A.
Deposit date:2010-07-22
Release date:2012-01-25
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nitrate as a probe of cytochrome c surface: crystallographic identification of crucial "hot spots" for protein-protein recognition.
J. Inorg. Biochem., 135, 2014
3U99
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THE EXPERIMENTAL X-RAY STRUCTURE OF THE NEW DIHEME CYTOCHROME TYPE C FROM SHEWANELLA BALTICA OS155 SB-DHC
Descriptor:Diheme cytochrome c, HEME C
Authors:De March, M., Di Rocco, G., Geremia, S.
Deposit date:2011-10-18
Release date:2012-10-31
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (1.146 Å)
Cite:High-resolution crystal structure of the recombinant diheme cytochrome c from Shewanella baltica (OS155).
J.Biomol.Struct.Dyn., 33, 2015
4R50
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT COCRYSTALLIZED WITH LI+
Descriptor:Potassium channel protein, (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCINE
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-08-20
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4R6Z
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK MUTANT, NAK-ETPP, CS+ COMPLEX
Descriptor:Potassium channel protein, CESIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-08-26
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4R7C
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT COCRYSTALLIZED WITH DIMETHYLAMMONIUM
Descriptor:Potassium channel protein, GLYCINE, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-08-27
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4R8C
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT IN COMPLEX WITH RB+
Descriptor:Potassium channel protein, RUBIDIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-09-01
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4RAI
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT IN COMPLEX WITH NA+
Descriptor:Potassium channel protein, SODIUM ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-09-10
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
4RO2
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-ETPP MUTANT COCRYSTALLIZED WITH METHYLAMMONIUM
Descriptor:Potassium channel protein, methylammonium ion, GLYCINE, ...
Authors:De March, M., Napolitano, L.M.R., Onesti, S.
Deposit date:2014-10-27
Release date:2015-07-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Proc.Natl.Acad.Sci.USA, 112, 2015
3TQ2
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MEROHEDRAL TWINNING IN PROTEIN CRYSTALS REVEALED A NEW SYNTHETIC THREE HELIX BUNDLE MOTIF
Descriptor:KE1, SULFATE ION
Authors:Geremia, S., De March, M.
Deposit date:2011-09-09
Release date:2012-09-26
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Merohedral twinning in protein crystals revealed a new synthetic three helix bundle motif
To be Published
6FIZ
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CRYSTAL STRUCTURE OF CNG MIMICKING NAK-EAPP MUTANT (T67A) COCRYSTALLIZED WITH K+
Descriptor:CNG mimic T67A mutant monomer, GLYCINE, POTASSIUM ION, ...
Authors:Napolitano, L.M.R., De March, M., Steiner, A.R., Onesti, S.
Deposit date:2018-01-19
Release date:2019-03-06
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:Crystal Structure of CNG mimicking NaK-EAPP mutant (T67A) cocrystallized with K+
To Be Published