1RFF | | CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTAPEPTIDE KLNYYDPR, AND TETRANUCLEOTIDE AGTT. | | Descriptor: | 5'-D(*AP*GP*TP*T)-3', Tyrosyl-DNA phosphodiesterase 1, Topoisomerase I-Derived Peptide, ... | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G. | | Deposit date: | 2003-11-08 | | Release date: | 2004-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
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1RFI | | CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, PENTAPEPTIDE KLNYK, AND TETRANUCLEOTIDE AGTC | | Descriptor: | 5'-D(*AP*GP*TP*C)-3', Tyrosyl-DNA phosphodiesterase 1, Topoisomerase I-Derived Peptide, ... | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G. | | Deposit date: | 2003-11-10 | | Release date: | 2004-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
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1RG1 | | CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE, AND TETRANUCLEOTIDE AGTT | | Descriptor: | 5'-D(*AP*GP*TP*T)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ... | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G. | | Deposit date: | 2003-11-10 | | Release date: | 2004-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
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1RG2 | | CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE, AND TETRANUCLEOTIDE AGTA | | Descriptor: | 5'-D(*AP*GP*TP*A)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ... | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G. | | Deposit date: | 2003-11-11 | | Release date: | 2004-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
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1RGT | | CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE, AND TETRANUCLEOTIDE AGTC | | Descriptor: | 5'-D(*AP*GP*TP*C)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ... | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G. | | Deposit date: | 2003-11-12 | | Release date: | 2004-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
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1RGU | | THE CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE, AND TETRANUCLEOTIDE AGTG | | Descriptor: | 5'-D(*AP*GP*TP*G)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ... | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G. | | Deposit date: | 2003-11-13 | | Release date: | 2004-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
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1RH0 | | CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE COMPLEXED WITH VANADATE, OCTOPAMINE AND TRINUCLEOTIDE GTT | | Descriptor: | 5'-D(*GP*TP*T)-3', Tyrosyl-DNA phosphodiesterase 1, VANADATE ION, ... | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G. | | Deposit date: | 2003-11-13 | | Release date: | 2004-03-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes.
J.Med.Chem., 47, 2004
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1NOP | | CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE (TDP1) IN COMPLEX WITH VANADATE, DNA AND A HUMAN TOPOISOMERASE I-DERIVED PEPTIDE | | Descriptor: | 5'-D(*AP*GP*AP*GP*TP*T)-3', tyrosyl-DNA phosphodiesterase 1, topoisomerase I-derived peptide, ... | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.J. | | Deposit date: | 2003-01-16 | | Release date: | 2003-03-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide
Chem.Biol., 10, 2003
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1MU7 | | CRYSTAL STRUCTURE OF A HUMAN TYROSYL-DNA PHOSPHODIESTERASE (TDP1)-TUNGSTATE COMPLEX | | Descriptor: | Tyrosyl-DNA Phosphodiesterase, TUNGSTATE(VI)ION, GLYCEROL | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.J. | | Deposit date: | 2002-09-23 | | Release date: | 2003-01-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2003
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1MU9 | | CRYSTAL STRUCTURE OF A HUMAN TYROSYL-DNA PHOSPHODIESTERASE (TDP1)-VANADATE COMPLEX | | Descriptor: | Tyrosyl-DNA Phosphodiesterase, VANADATE ION, GLYCEROL | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.J. | | Deposit date: | 2002-09-23 | | Release date: | 2003-01-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures
J.Mol.Biol., 324, 2002
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1B7E | | TRANSPOSASE INHIBITOR | | Descriptor: | PROTEIN (TRANSPOSASE INHIBITOR PROTEIN FROM TN5), 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride | | Authors: | Davies, D.R., Braam, L.M., Reznikoff, W.S., Rayment, I. | | Deposit date: | 1999-01-22 | | Release date: | 1999-04-21 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The three-dimensional structure of a Tn5 transposase-related protein determined to 2.9A resolution.
J.Biol.Chem., 274, 1999
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1JY1 | | CRYSTAL STRUCTURE OF HUMAN TYROSYL-DNA PHOSPHODIESTERASE (TDP1) | | Descriptor: | TYROSYL-DNA PHOSPHODIESTERASE | | Authors: | Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G.J. | | Deposit date: | 2001-09-10 | | Release date: | 2002-02-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1.
Structure, 10, 2002
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2B9S | | CRYSTAL STRUCTURE OF HETERODIMERIC L. DONOVANI TOPOISOMERASE I-VANADATE-DNA COMPLEX | | Descriptor: | 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T)-3', 5'-D(*AP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', 5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3', ... | | Authors: | Davies, D.R., Hol, W.G.J. | | Deposit date: | 2005-10-12 | | Release date: | 2006-01-17 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | The Structure of the Transition State of the Heterodimeric Topoisomerase I of Leishmania donovani as a Vanadate Complex with Nicked DNA.
J.Mol.Biol., 357, 2006
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3FTS | | LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH RESVERATROL | | Descriptor: | Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ... | | Authors: | Davies, D.R. | | Deposit date: | 2009-01-13 | | Release date: | 2009-07-28 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.33 Å) | | Cite: | Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
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3FTU | | LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH DIHYDRORESVERATROL | | Descriptor: | Leukotriene A-4 hydrolase, ZINC ION, YTTERBIUM (III) ION, ... | | Authors: | Davies, D.R. | | Deposit date: | 2009-01-13 | | Release date: | 2009-07-28 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography.
J.Med.Chem., 52, 2009
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3FTV | |
3FTW | |
3FTX | |
3FTY | |
3FU0 | |
3FU3 | |
3FU5 | |
3FU6 | |
3FUD | |
3FUE | |
