1MU7
Crystal Structure of a Human Tyrosyl-DNA Phosphodiesterase (Tdp1)-Tungstate Complex
Summary for 1MU7
| Entry DOI | 10.2210/pdb1mu7/pdb |
| Related | 1jy1 1mu9 |
| Descriptor | Tyrosyl-DNA Phosphodiesterase, TUNGSTATE(VI)ION, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | pld superfamily, protein-tungstate complex, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 110142.25 |
| Authors | Davies, D.R.,Interthal, H.,Champoux, J.J.,Hol, W.G.J. (deposition date: 2002-09-23, release date: 2003-01-07, Last modification date: 2024-02-14) |
| Primary citation | Davies, D.R.,Interthal, H.,Champoux, J.J.,Hol, W.G.J. Insights Into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate- and Tungstate-Inhibited Structures J.Mol.Biol., 324:917-932, 2003 Cited by PubMed: 12470949DOI: 10.1016/S0022-2836(02)01154-3 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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