2L7V
| Quindoline/G-quadruplex complex | Descriptor: | DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), N,N-diethyl-N'-(10H-indolo[3,2-b]quinolin-11-yl)ethane-1,2-diamine, POTASSIUM ION | Authors: | Dai, J, Carver, M, Mathad, R, Yang, D. | Deposit date: | 2010-12-23 | Release date: | 2011-11-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution Structure of a 2:1 Quindoline-c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design. J.Am.Chem.Soc., 133, 2011
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8TJT
| The Fab fragment of an anti-glucagon receptor (GCGR) antibody | Descriptor: | anti-GCGR Fab heavy chain, anti-GCGR Fab light chain | Authors: | Dai, J, Carter, P.J, Sudhamsu, J, Kung, J. | Deposit date: | 2023-07-24 | Release date: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG 1 antibody. Mabs, 16, 2024
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8EAW
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6X0Q
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6X0R
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1S1D
| Structure and protein design of human apyrase | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Dai, J, Liu, J, Deng, Y, Smith, T.M, Lu, M. | Deposit date: | 2004-01-06 | Release date: | 2004-03-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure and protein design of a human platelet function inhibitor. Cell(Cambridge,Mass.), 116, 2004
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1S18
| Structure and protein design of human apyrase | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Dai, J, Liu, J, Deng, Y, Smith, T.M, Lu, M. | Deposit date: | 2004-01-05 | Release date: | 2004-03-16 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure and protein design of a human platelet function inhibitor. Cell(Cambridge,Mass.), 116, 2004
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6RMN
| DNA mismatch repair proteins MLH1 and MLH3 | Descriptor: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | Authors: | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | Deposit date: | 2019-05-07 | Release date: | 2021-05-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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6SHX
| DNA mismatch repair proteins MLH1 and MLH3 | Descriptor: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | Authors: | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | Deposit date: | 2019-08-08 | Release date: | 2021-05-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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6SNS
| DNA mismatch repair proteins MLH1 and MLH3 | Descriptor: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | Authors: | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | Deposit date: | 2019-08-27 | Release date: | 2021-05-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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6SNV
| DNA mismatch repair proteins MLH1 and MLH3 | Descriptor: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | Authors: | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | Deposit date: | 2019-08-27 | Release date: | 2021-05-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation. Proc.Natl.Acad.Sci.USA, 118, 2021
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1X95
| Solution structure of the DNA-hexamer ATGCAT complexed with DNA Bis-intercalating Anticancer Drug XR5944 (MLN944) | Descriptor: | 1-METHYL-9-[12-(9-METHYLPHENAZIN-10-IUM-1-YL)-12-OXO-2,11-DIAZA-5,8-DIAZONIADODEC-1-ANOYL]PHENAZIN-10-IUM, 5'-D(*AP*TP*GP*CP*AP*T)-3' | Authors: | Dai, J, Punchihewa, C, Mistry, P, Ooi, A.T, Yang, D. | Deposit date: | 2004-08-19 | Release date: | 2004-09-28 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug. J.Biol.Chem., 279, 2004
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2HY9
| Human telomere DNA quadruplex structure in K+ solution hybrid-1 form | Descriptor: | DNA (26-MER) | Authors: | Dai, J, Punchihewa, C, Jones, R.A, Hurley, L, Yang, D. | Deposit date: | 2006-08-04 | Release date: | 2007-04-10 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation. Nucleic Acids Res., 35, 2007
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2JPZ
| Human telomere DNA quadruplex structure in K+ solution hybrid-2 form | Descriptor: | DNA (26-MER) | Authors: | Dai, J, Carver, M, Punchihewa, C, Jones, R, Yang, D. | Deposit date: | 2007-05-25 | Release date: | 2007-12-04 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the Hybrid-2 type intramolecular human telomeric G-quadruplex in K+ solution: insights into structure polymorphism of the human telomeric sequence Nucleic Acids Res., 35, 2007
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9B4H
| Chlamydomonas reinhardtii mastigoneme filament | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain-containing protein, Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein, ... | Authors: | Dai, J, Ma, M, Zhang, R, Brown, A. | Deposit date: | 2024-03-20 | Release date: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices. Cell, 2024
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2F8U
| G-quadruplex structure formed in human Bcl-2 promoter, hybrid form | Descriptor: | 5'-D(*GP*GP*GP*CP*GP*CP*GP*GP*GP*AP*GP*GP*AP*AP*TP*TP*GP*GP*GP*CP*GP*GP*G)-3' | Authors: | Dai, J, Chen, D, Carver, M, Yang, D. | Deposit date: | 2005-12-03 | Release date: | 2006-11-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region. Nucleic Acids Res., 34, 2006
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7DHP
| Crystal structure of MazF from Deinococcus radiodurans | Descriptor: | Endoribonuclease MazF, SULFATE ION | Authors: | Zhao, Y, Dai, J. | Deposit date: | 2020-11-17 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | MazEF Toxin-Antitoxin System-Mediated DNA Damage Stress Response in Deinococcus radiodurans. Front Genet, 12, 2021
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4QQV
| Extracellular domains of mouse IL-3 beta receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-3 receptor class 2 subunit beta | Authors: | Jackson, C.J, Young, I.G, Murphy, J.M, Carr, P.D, Ewens, C.L, Dai, J, Ollis, D.L. | Deposit date: | 2014-06-30 | Release date: | 2014-09-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Crystal structure of the mouse interleukin-3 beta-receptor: insights into interleukin-3 binding and receptor activation. Biochem.J., 463, 2014
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1JCC
| Crystal Structure of a Novel Alanine-Zipper Trimer at 1.7 A Resolution, V13A,L16A,V20A,L23A,V27A,M30A,V34A mutations | Descriptor: | MAJOR OUTER MEMBRANE LIPOPROTEIN, ZINC ION | Authors: | Liu, J, Dai, J, Lu, M. | Deposit date: | 2001-06-08 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Zinc-Mediated Helix Capping in A Triple-Helical Protein Biochemistry, 42, 2003
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1SWV
| Crystal structure of the D12A mutant of phosphonoacetaldehyde hydrolase complexed with magnesium | Descriptor: | MAGNESIUM ION, phosphonoacetaldehyde hydrolase | Authors: | Zhang, G, Morais, M.C, Dai, J, Zhang, W, Dunaway-Mariano, D, Allen, K.N. | Deposit date: | 2004-03-30 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily Biochemistry, 43, 2004
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1SWW
| Crystal structure of the phosphonoacetaldehyde hydrolase D12A mutant complexed with magnesium and substrate phosphonoacetaldehyde | Descriptor: | MAGNESIUM ION, PHOSPHONOACETALDEHYDE, phosphonoacetaldehyde hydrolase | Authors: | Zhang, G, Morais, M.C, Dai, J, Zhang, W, Dunaway-Mariano, D, Allen, K.N. | Deposit date: | 2004-03-30 | Release date: | 2004-10-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily Biochemistry, 43, 2004
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1XAV
| Major G-quadruplex structure formed in human c-MYC promoter, a monomeric parallel-stranded quadruplex | Descriptor: | 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3', POTASSIUM ION | Authors: | Ambrus, A, Chen, D, Dai, J, Jones, R.A, Yang, D. | Deposit date: | 2004-08-26 | Release date: | 2005-02-01 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Solution structure of the biologically relevant G-Quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization. Biochemistry, 44, 2005
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1Z4O
| Structure of beta-phosphoglucomutase with inhibitor bound alpha-galactose 1-phosphate | Descriptor: | 1-O-phosphono-alpha-D-galactopyranose, Beta-phosphoglucomutase, MAGNESIUM ION | Authors: | Tremblay, L.W, Zhang, G, Dai, J, Dunaway-Mariano, D, Allen, K.N. | Deposit date: | 2005-03-16 | Release date: | 2005-04-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Chemical Confirmation of a Pentavalent Phosphorane in Complex with beta-Phosphoglucomutase J.Am.Chem.Soc., 127, 2005
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1Z4N
| Structure of beta-phosphoglucomutase with inhibitor bound alpha-galactose 1-phosphate cocrystallized with Fluoride | Descriptor: | 1-O-phosphono-alpha-D-galactopyranose, Beta-phosphoglucomutase, MAGNESIUM ION | Authors: | Tremblay, L.W, Zhang, G, Dai, J, Dunaway-Mariano, D, Allen, K.N. | Deposit date: | 2005-03-16 | Release date: | 2005-04-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Chemical Confirmation of a Pentavalent Phosphorane in Complex with beta-Phosphoglucomutase J.Am.Chem.Soc., 127, 2005
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1ZOL
| native beta-PGM | Descriptor: | MAGNESIUM ION, beta-phosphoglucomutase | Authors: | Zhang, G, Tremblay, L.W, Dai, J, Wang, L, Dunaway-Mariano, D, Allen, K.N. | Deposit date: | 2005-05-13 | Release date: | 2005-08-30 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Catalytic cycling in beta-phosphoglucomutase: a kinetic and structural analysis Biochemistry, 44, 2005
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