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1A3Q
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BU of 1a3q by Molmil
HUMAN NF-KAPPA-B P52 BOUND TO DNA
Descriptor: DNA (5'-D(*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*AP*TP*TP*CP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B P52)
Authors:Cramer, P, Larson, C.J, Verdine, G.L, Muller, C.W.
Deposit date:1998-01-23
Release date:1998-06-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the human NF-kappaB p52 homodimer-DNA complex at 2.1 A resolution.
EMBO J., 16, 1997
1I3Q
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BU of 1i3q by Molmil
RNA POLYMERASE II CRYSTAL FORM I AT 3.1 A RESOLUTION
Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ...
Authors:Cramer, P, Bushnell, D.A, Kornberg, R.D.
Deposit date:2001-02-15
Release date:2001-04-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science, 292, 2001
1I50
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BU of 1i50 by Molmil
RNA POLYMERASE II CRYSTAL FORM II AT 2.8 A RESOLUTION
Descriptor: DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.2KD POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 14.5KD POLYPEPTIDE, ...
Authors:Cramer, P, Bushnell, D.A, Kornberg, R.D.
Deposit date:2001-02-23
Release date:2001-04-23
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution.
Science, 292, 2001
1BVO
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BU of 1bvo by Molmil
DORSAL HOMOLOGUE GAMBIF1 BOUND TO DNA
Descriptor: DNA DUPLEX, TRANSCRIPTION FACTOR GAMBIF1
Authors:Cramer, P, Varrot, A, Barillas-Mury, C, Kafatos, F.C, Mueller, C.W.
Deposit date:1998-09-16
Release date:1999-07-12
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA.
Structure Fold.Des., 7, 1999
1Y1W
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BU of 1y1w by Molmil
Complete RNA Polymerase II elongation complex
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*T)-3', 5'-D(P*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*AP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ...
Authors:Cramer, P, Kettenberger, H, Armache, K.-J.
Deposit date:2004-11-19
Release date:2005-01-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (4 Å)
Cite:Complete RNA Polymerase II Elongation Complex Structure and Its Interactions with NTP and TFIIS
Mol.Cell, 16, 2004
1Y1Y
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BU of 1y1y by Molmil
RNA Polymerase II-TFIIS-DNA/RNA complex
Descriptor: 5'-D(P*TP*AP*CP*GP*CP*CP*T)-3', 5'-R(P*AP*GP*GP*C)-3', DNA-directed RNA polymerase II 13.6 kDa polypeptide, ...
Authors:Cramer, P, Kettenberger, H, Armache, K.-J.
Deposit date:2004-11-19
Release date:2004-12-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.
Mol.Cell, 16, 2004
3K1F
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BU of 3k1f by Molmil
Crystal structure of RNA Polymerase II in complex with TFIIB
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Kostrewa, D, Zeller, M.E, Armache, K.-J, Seizl, M, Leike, K, Thomm, M, Cramer, P.
Deposit date:2009-09-27
Release date:2009-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4.3 Å)
Cite:RNA polymerase II-TFIIB structure and mechanism of transcription initiation.
Nature, 462, 2009
2HZM
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BU of 2hzm by Molmil
Structure of the Mediator head subcomplex Med18/20
Descriptor: PHOSPHATE ION, RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20
Authors:Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P.
Deposit date:2006-08-09
Release date:2006-09-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
8A40
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BU of 8a40 by Molmil
Structure of mammalian Pol II-TFIIS elongation complex
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P.
Deposit date:2022-06-09
Release date:2023-08-23
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of a backtracked hexasomal intermediate of nucleosome transcription.
Mol.Cell, 82, 2022
8A3Y
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BU of 8a3y by Molmil
Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P.
Deposit date:2022-06-09
Release date:2024-07-31
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of a backtracked hexasomal intermediate of nucleosome transcription.
Mol.Cell, 82, 2022
4V1N
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BU of 4v1n by Molmil
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
4V1O
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BU of 4v1o by Molmil
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
Descriptor: DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ...
Authors:Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
4V1M
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BU of 4v1m by Molmil
Architecture of the RNA polymerase II-Mediator core transcription initiation complex
Descriptor: 5'-D(*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-D(*CP*CP*AP*GP*GP*AP)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*CP *CP*BRUP*GP*GP*TP*C)-3', ...
Authors:Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P.
Deposit date:2014-09-29
Release date:2015-02-04
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Architecture of the RNA Polymerase II-Mediator Core Initiation Complex.
Nature, 518, 2015
4YM7
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BU of 4ym7 by Molmil
RNA polymerase I structure with an alternative dimer hinge
Descriptor: DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ...
Authors:Kostrewa, D, Kuhn, C.-D, Engel, C, Cramer, P.
Deposit date:2015-03-06
Release date:2015-09-09
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:An alternative RNA polymerase I structure reveals a dimer hinge.
Acta Crystallogr.,Sect.D, 71, 2015
1I6H
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BU of 1i6h by Molmil
RNA POLYMERASE II ELONGATION COMPLEX
Descriptor: 5'-D(P*AP*AP*AP*TP*GP*CP*CP*TP*GP*GP*TP*CP*T)-3', 5'-R(P*GP*AP*CP*CP*AP*GP*GP*CP*A)-3', DNA-DIRECTED RNA POLYMERASE II 13.6KD POLYPEPTIDE, ...
Authors:Gnatt, A.L, Cramer, P, Kornberg, R.D.
Deposit date:2001-03-02
Release date:2001-04-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution.
Science, 292, 2001
6ERQ
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BU of 6erq by Molmil
Structure of the human mitochondrial transcription initiation complex at the HSP promoter
Descriptor: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ...
Authors:Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
6I84
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BU of 6i84 by Molmil
Structure of transcribing RNA polymerase II-nucleosome complex
Descriptor: DNA (158-MER), DNA (170-MER), DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Farnung, L, Vos, S.M, Cramer, P.
Deposit date:2018-11-19
Release date:2019-01-02
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of transcribing RNA polymerase II-nucleosome complex.
Nat Commun, 9, 2018
5CE7
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BU of 5ce7 by Molmil
Structure of a non-canonical CID of Ctk3
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CTD kinase subunit gamma
Authors:Muehlbacher, W, Mayer, A, Sun, M, Remmert, M, Cheung, A.C, Niesser, J, Soeding, J, Cramer, P.
Deposit date:2015-07-06
Release date:2015-08-05
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain fold.
Proteins, 83, 2015
6ERO
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BU of 6ero by Molmil
Structure of human TFB2M
Descriptor: CHLORIDE ION, Dimethyladenosine transferase 2, mitochondrial,Dimethyladenosine transferase 2, ...
Authors:Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
6ERP
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BU of 6erp by Molmil
Structure of the human mitochondrial transcription initiation complex at the LSP promoter
Descriptor: DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ...
Authors:Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P.
Deposit date:2017-10-18
Release date:2017-11-15
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (4.502 Å)
Cite:Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
6EXV
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BU of 6exv by Molmil
Structure of mammalian RNA polymerase II elongation complex inhibited by Alpha-amanitin
Descriptor: AMATOXIN, DNA (25-MER), DNA (36-MER), ...
Authors:Liu, X, Farnung, L, Wigge, C, Cramer, P.
Deposit date:2017-11-09
Release date:2018-03-21
Last modified:2025-04-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of a mammalian RNA polymerase II elongation complex inhibited by alpha-amanitin.
J. Biol. Chem., 293, 2018
7ZWD
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BU of 7zwd by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-19
Release date:2022-11-30
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZX7
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BU of 7zx7 by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-20
Release date:2022-11-30
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZXE
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BU of 7zxe by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
Descriptor: Non-template strand, TATA-box-binding protein, Template strand, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-20
Release date:2022-11-30
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZX8
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BU of 7zx8 by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-20
Release date:2022-12-07
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022

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