Author results

3ZTN
  • Download 3ztn
  • View 3ztn
Molmil generated image of 3ztn
STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H1 INFLUENZA HAEMAGGLUTININ.
Descriptor:HAEMAGGLUTININ, FI6V3 ANTIBODY LIGHT CHAIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hubbard, P.A., Ritchie, A.J., Corti, D., Voss, J.E., Gamblin, S.J., Codoni, G., Macagno, A., Jarrossay, D., Pinna, D., Minola, A., Vanzetta, F., Silacci, C., Fernandez-Rodriguez, B.M., Agatic, G., Giacchetto-Sasselli, I., Vachieri, S.G., Sallusto, F., Collins, P.J., Haire, L.F., Temperton, N., Langedijk, J.P.M., Skehel, J.J., Lanzavecchia, A.
Deposit date:2011-07-12
Release date:2011-08-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.001 Å)
Cite:A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
6X79
  • Download 6x79
  • View 6x79
Molmil generated image of 6x79
PREFUSION SARS-COV-2 S ECTODOMAIN TRIMER COVALENTLY STABILIZED IN THE CLOSED CONFORMATION
Descriptor:SARS-CoV-2 spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:McCallum, M., Walls, A.C., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-05-29
Release date:2020-08-19
Last modified:2020-10-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure-guided covalent stabilization of coronavirus spike glycoprotein trimers in the closed conformation.
Nat.Struct.Mol.Biol., 27, 2020
6WPS
  • Download 6wps
  • View 6wps
Molmil generated image of 6wps
STRUCTURE OF THE SARS-COV-2 SPIKE GLYCOPROTEIN IN COMPLEX WITH THE S309 NEUTRALIZING ANTIBODY FAB FRAGMENT
Descriptor:SARS-CoV-2 spike glycoprotein, S309 neutralizing antibody heavy chain, S309 neutralizing antibody light chain, ...
Authors:Pinto, D., Park, Y.J., Beltramello, M., Walls, A.C., Tortorici, M.A., Bianchi, S., Jaconi, S., Culap, K., Zatta, F., De Marco, A., Peter, A., Guarino, B., Spreafico, R., Cameroni, E., Case, J.B., Chen, R.E., Havenar-Daughton, C., Snell, G., Virgin, H.W., Lanzavecchia, A., Diamond, M.S., Fink, K., Veesler, D., Corti, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-27
Release date:2020-05-27
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and functional analysis of a potent sarbecovirus neutralizing antibody.
Biorxiv, 2020
6WPT
  • Download 6wpt
  • View 6wpt
Molmil generated image of 6wpt
STRUCTURE OF THE SARS-COV-2 SPIKE GLYCOPROTEIN IN COMPLEX WITH THE S309 NEUTRALIZING ANTIBODY FAB FRAGMENT (OPEN STATE)
Descriptor:SARS-CoV-2 spike glycoprotein, S309 neutralizing antibody heavy chain, S309 neutralizing antibody light chain, ...
Authors:Pinto, D., Park, Y.J., Beltramello, M., Walls, A.C., Tortorici, M.A., Bianchi, S., Jaconi, S., Culap, K., Zatta, F., De Marco, A., Peter, A., Guarino, B., Spreafico, R., Cameroni, E., Case, J.B., Chen, R.E., Havenar-Daughton, C., Snell, G., Virgin, H.W., Lanzavecchia, A., Diamond, M.S., Fink, K., Veesler, D., Corti, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-27
Release date:2020-05-27
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural and functional analysis of a potent sarbecovirus neutralizing antibody.
Biorxiv, 2020
6WS6
  • Download 6ws6
  • View 6ws6
Molmil generated image of 6ws6
STRUCTURAL AND FUNCTIONAL ANALYSIS OF A POTENT SARBECOVIRUS NEUTRALIZING ANTIBODY
Descriptor:S309 antigen-binding (Fab) fragment, heavy chain, light chain, ...
Authors:Pinto, D., Park, Y.J., Beltramello, M., Walls, A.C., Tortorici, M.A., Bianchi, S., Jaconi, S., Culap, K., Zatta, F., Marco, A.D., Peter, A., Guarino, B., Spreafico, R., Cameroni, E., Case, J.B., Chen, R.E., Havenar-Daughton, C., Snell, G., Telenti, A., Virgin, H.W., Lanzavecchia, A., Diamond, M.S., Fink, K., Veesler, D., Corti, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-04-30
Release date:2020-05-27
Last modified:2020-06-24
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and functional analysis of a potent sarbecovirus neutralizing antibody.
Biorxiv, 2020
7JX3
  • Download 7jx3
  • View 7jx3
Molmil generated image of 7jx3
MAPPING NEUTRALIZING AND IMMUNODOMINANT SITES ON THE SARS-COV-2 SPIKE RECEPTOR-BINDING DOMAIN BY STRUCTURE-GUIDED HIGH-RESOLUTION SEROLOGY
Descriptor:Light chain of Fab domain of monoclonal antibody S309, Heavy chain of Fab domain of monoclonal antibody S309, Light chain of Fab domain of monoclonal antibody S2H14, ...
Authors:Snell, G., Czudnochowski, N., Rosen, L.E., Nix, J.C., Corti, D., Veesler, D., Park, Y.J., Walls, A.C., Tortorici, M.A., Cameroni, E., Pinto, D., Beltramello, M.
Deposit date:2020-08-26
Release date:2020-10-14
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
6NB3
  • Download 6nb3
  • View 6nb3
Molmil generated image of 6nb3
MERS-COV COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, LCA60 light chain, LCA60 heavy chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB4
  • Download 6nb4
  • View 6nb4
Molmil generated image of 6nb4
MERS-COV S COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, LCA60 heavy chain, LCA60 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB6
  • Download 6nb6
  • View 6nb6
Molmil generated image of 6nb6
SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB7
  • Download 6nb7
  • View 6nb7
Molmil generated image of 6nb7
SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6SNC
  • Download 6snc
  • View 6snc
Molmil generated image of 6snc
CRYSTAL STRUCTURE OF LN01 FAB IN COMPLEX WITH AN HIV-1 GP41 PEPTIDE
Descriptor:LNO1 Light Chain, LNO1 Heavy Chain, Envelope glycoprotein gp160, ...
Authors:Caillat, C., Pinto, D., Corti, D., Fenwick, C., Pantaleo, G., Weissenhorn, W.
Deposit date:2019-08-23
Release date:2019-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26, 2019
6SND
  • Download 6snd
  • View 6snd
Molmil generated image of 6snd
CRYSTAL STRUCTURE OF LN01 FAB IN COMPLEX WITH AN HIV-1 GP41 PEPTIDE
Descriptor:LN01 light chain, LN01 heavy chain, Envelope glycoprotein gp160, ...
Authors:Caillat, C., Pinto, D., Corti, D., Fenwick, C., Pantaleo, G., Weissenhorn, W.
Deposit date:2019-08-23
Release date:2019-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26, 2019
6SNE
  • Download 6sne
  • View 6sne
Molmil generated image of 6sne
CRYSTAL STRUCTURE OF LN01 FAB IN COMPLEX WITH AN HIV-1 GP41 PEPTIDE
Descriptor:Envelope glycoprotein gp160, LN01 light chain, LN01 heavy chain, ...
Authors:Caillat, C., Pinto, D., Corti, D., Fenwick, C., Pantaleo, G., Weissenhorn, W.
Deposit date:2019-08-23
Release date:2019-11-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural Basis for Broad HIV-1 Neutralization by the MPER-Specific Human Broadly Neutralizing Antibody LN01.
Cell Host Microbe, 26, 2019
2XRA
  • Download 2xra
  • View 2xra
Molmil generated image of 2xra
CRYSTAL STRUCTURE OF THE HK20 FAB IN COMPLEX WITH A GP41 MIMETIC 5- HELIX
Descriptor:TRANSMEMBRANE PROTEIN GP41, HK20, HUMAN MONOCLONAL ANTIBODY HEAVY CHAIN, ...
Authors:Sabin, C., Corti, D., Buzon, V., Seaman, M.S., Lutje Hulsik, D., Hinz, A., Vanzetta, F., Agatic, G., Silacci, C., Langedijk, J.P.M., Mainetti, L., Scarlatti, G., Sallusto, F., Weiss, R., Lanzavecchia, A., Weissenhorn, W.
Deposit date:2010-09-13
Release date:2010-12-15
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure and size-dependent neutralization properties of HK20, a human monoclonal antibody binding to the highly conserved heptad repeat 1 of gp41.
PLoS Pathog., 6, 2010
5A3I
  • Download 5a3i
  • View 5a3i
Molmil generated image of 5a3i
CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN FLD194 FAB AND TRANSMISSIBLE MUTANT H5 HAEMAGGLUTININ
Descriptor:HEMAGGLUTININ, ANTI-HAEMAGGLUTININ HA1 FAB HEAVY CHAIN, ANTI-HAEMAGGLUTININ HA1 FAB LIGHT CHAIN, ...
Authors:Xiong, X., Corti, D., Liu, J., Pinna, D., Foglierini, M., Calder, L.J., Martin, S.R., Lin, Y.P., Walker, P.A., Collins, P.J., Monne, I., Suguitan Jr, A.L., Santos, C., Temperton, N.J., Subbarao, K., Lanzavecchia, A., Gamblin, S.J., Skehel, J.J.
Deposit date:2015-06-01
Release date:2015-07-22
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structures of Complexes Formed by H5 Influenza Hemagglutinin with a Potent Broadly Neutralizing Human Monoclonal Antibody.
Proc.Natl.Acad.Sci.USA, 112, 2015
6NB5
  • Download 6nb5
  • View 6nb5
Molmil generated image of 6nb5
CRYSTAL STRUCTURE OF ANTI- MERS-COV HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT
Descriptor:LCA60 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB8
  • Download 6nb8
  • View 6nb8
Molmil generated image of 6nb8
CRYSTAL STRUCTURE OF ANTI- SARS-COV HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT
Descriptor:S230 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6LNT
  • Download 6lnt
  • View 6lnt
Molmil generated image of 6lnt
CRYO-EM STRUCTURE OF IMMATURE ZIKA VIRUS IN COMPLEX WITH HUMAN ANTIBODY DV62.5 FAB
Descriptor:Envelope protein, pre-membrane protein, Fab DV62.5 heavy-chain variable region, ...
Authors:Tan, T.Y., Fibriansah, G., Kostyuchenko, V.A., Ng, T.S., Lim, X.X., Lim, X.N., Shi, J., Morais, M.C., Corti, D., Lok, S.M.
Deposit date:2020-01-02
Release date:2020-02-26
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
6LNU
  • Download 6lnu
  • View 6lnu
Molmil generated image of 6lnu
CRYO-EM STRUCTURE OF IMMATURE ZIKA VIRUS
Descriptor:Genome polyprotein
Authors:Tan, T.Y., Fibriansah, G., Kostyuchenko, V.A., Ng, T.S., Lim, X.X., Lim, X.N., Shi, J., Morais, M.C., Corti, D., Lok, S.M.
Deposit date:2020-01-02
Release date:2020-02-26
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Capsid protein structure in Zika virus reveals the flavivirus assembly process.
Nat Commun, 11, 2020
3ZTJ
  • Download 3ztj
  • View 3ztj
Molmil generated image of 3ztj
STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H3 INFLUENZA HAEMAGGLUTININ.
Descriptor:HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN, FI6V3 ANTIBODY HEAVY CHAIN, ...
Authors:Voss, J.E., Vachieri, S.G., Gamblin, S.J., Collins, P.J., Haire, L.F., Skehel, J.J.
Deposit date:2011-07-08
Release date:2011-08-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
7JV2
  • Download 7jv2
  • View 7jv2
Molmil generated image of 7jv2
SARS-COV-2 SPIKE IN COMPLEX WITH THE S2H13 NEUTRALIZING ANTIBODY FAB FRAGMENT (LOCAL REFINEMENT OF THE RECEPTOR-BINDING MOTIF AND FAB VARIABLE DOMAINS)
Descriptor:S2H13 Fab heavy chain, S2H13 Fab light chain, SARS-CoV-2 spike glycoprotein
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JV4
  • Download 7jv4
  • View 7jv4
Molmil generated image of 7jv4
SARS-COV-2 SPIKE IN COMPLEX WITH THE S2H13 NEUTRALIZING ANTIBODY (ONE RBD OPEN)
Descriptor:SARS-CoV-2 spike glycoprotein, S2H13 Fab heavy chain, S2H13 Fab light chain, ...
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JV6
  • Download 7jv6
  • View 7jv6
Molmil generated image of 7jv6
SARS-COV-2 SPIKE IN COMPLEX WITH THE S2H13 NEUTRALIZING ANTIBODY (CLOSED CONFORMATION)
Descriptor:SARS-CoV-2 spike glycoprotein, S2H13 Fab heavy chain, S2H13 Fab light chain, ...
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JVA
  • Download 7jva
  • View 7jva
Molmil generated image of 7jva
SARS-COV-2 SPIKE IN COMPLEX WITH THE S2A4 NEUTRALIZING ANTIBODY FAB FRAGMENT (LOCAL REFINEMENT OF THE RECEPTOR-BINDING DOMAIN AND FAB VARIABLE DOMAINS)
Descriptor:S2A4 Fab heavy chain, S2A4 Fab light chain, SARS-CoV-2 spike glycoprotein, ...
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
7JVC
  • Download 7jvc
  • View 7jvc
Molmil generated image of 7jvc
SARS-COV-2 SPIKE IN COMPLEX WITH THE S2A4 NEUTRALIZING ANTIBODY FAB FRAGMENT
Descriptor:SARS-CoV-2 spike glycoprotein, S2A4 Fab heavy chain, S2A4 Fab light chain, ...
Authors:Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-20
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
<123>
170172
PDB entries from 2020-10-21