Author results

2JIS
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HUMAN CYSTEINE SULFINIC ACID DECARBOXYLASE (CSAD) IN COMPLEX WITH PLP.
Descriptor:CYSTEINE SULFINIC ACID DECARBOXYLASE, PYRIDOXAL-5'-PHOSPHATE, NITRATE ION
Authors:Collins, R., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2007-06-30
Release date:2007-08-28
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The Crystal Structure of Human Cysteine Sulfinic Acid Decarboxylase (Csad)
To be Published
3GZC
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STRUCTURE OF HUMAN SELENOCYSTEINE LYASE
Descriptor:Selenocysteine lyase, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE
Authors:Collins, R., Hogbom, M., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Karlberg, T., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-04-07
Release date:2009-04-28
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase.
Plos One, 7, 2012
3COG
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CRYSTAL STRUCTURE OF HUMAN CYSTATHIONASE (CYSTATHIONINE GAMMA LYASE) IN COMPLEX WITH DL-PROPARGYLGLYCINE
Descriptor:Cystathionine gamma-lyase, NITRATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Collins, R., Karlberg, T., Lehtio, L., Arrowsmith, C.H., Berglund, H., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Olesen, K., Persson, C., Schuler, H., Svensson, L., Thorsell, A.G., Tresaugues, L., Van den Berg, S., Sagermark, J., Busam, R.D., Welin, M., Weigelt, J., Wikstrom, M., Structural Genomics Consortium (SGC)
Deposit date:2008-03-28
Release date:2008-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S.
J.Biol.Chem., 284, 2009
3EWS
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HUMAN DEAD-BOX RNA-HELICASE DDX19 IN COMPLEX WITH ADP
Descriptor:ATP-dependent RNA helicase DDX19B, ADENOSINE-5'-DIPHOSPHATE
Authors:Lehtio, l., Karlberg, t., Andersson, j., Arrowsmith, c.h., Berglund, h., Bountra, c., Collins, r., Dahlgren, l.g., Edwards, a.m., Flodin, s., Flores, a., Graslund, s., Hammarstrom, m., Johansson, a., Johansson, i., Kotenyova, t., Moche, m., Nilsson, m.e., Nordlund, p., Nyman, t., Olesen, k., Persson, c., Sagemark, j., Thorsell, a.g., Tresaugues, l., Van den berg, s., Weigelt, j., Welin, m., Wikstrom, m., Wisniewska, m., Schueler, h., Structural Genomics Consortium (SGC)
Deposit date:2008-10-16
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch.
J.Biol.Chem., 284, 2009
3G0H
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HUMAN DEAD-BOX RNA HELICASE DDX19, IN COMPLEX WITH AN ATP-ANALOGUE AND RNA
Descriptor:ATP-dependent RNA helicase DDX19B, 5'-R(P*UP*UP*UP*UP*UP*UP*U)-3', PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Karlberg, T., Lehtio, L., Collins, R., Arrowsmith, C.H., Berglund, H., Bountra, C., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Schutz, P., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-01-28
Release date:2009-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch.
J.Biol.Chem., 284, 2009
3GZD
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HUMAN SELENOCYSTEINE LYASE, P1 CRYSTAL FORM
Descriptor:Selenocysteine lyase, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, NITRATE ION
Authors:Karlberg, T., Hogbom, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Schutz, P., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2009-04-07
Release date:2009-04-28
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Biochemical discrimination between selenium and sulfur 1: a single residue provides selenium specificity to human selenocysteine lyase.
Plos One, 7, 2012
2J91
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CRYSTAL STRUCTURE OF HUMAN ADENYLOSUCCINATE LYASE IN COMPLEX WITH AMP
Descriptor:ADENYLOSUCCINATE LYASE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Stenmark, P., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2006-11-01
Release date:2006-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of Human Adenylosuccinate Lyase
To be Published
2JCN
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THE CRYSTAL STRUCTURE OF BAK1 - A MITOCHONDRIAL APOPTOSIS REGULATOR
Descriptor:BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, SULFATE ION
Authors:Moche, M., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Lundgren, S., Nilsson, M.E., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2006-12-27
Release date:2007-01-04
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of Bak1 - an Apoptosis Trigger in the Mitochondrial Outer Membrane
To be Published
2JEO
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CRYSTAL STRUCTURE OF HUMAN URIDINE-CYTIDINE KINASE 1
Descriptor:URIDINE-CYTIDINE KINASE 1
Authors:Kosinska, U., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E.P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2007-01-18
Release date:2007-01-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Human Uridine-Cytidine Kinase 1
To be Published
2JI4
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HUMAN PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE - ASSOCIATED PROTEIN 41 (PAP41)
Descriptor:PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE-ASSOCIATED PROTEIN 2, CHLORIDE ION
Authors:Moche, M., Lehtio, L., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Karlberg, T., Kotenyova, T., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P.
Deposit date:2007-02-26
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Human Phosphoribosylpyrophosphate Synthetase -Associated Protein 41 (Pap41)
To be Published
2QQ2
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF HUMAN ACYL-COA THIOESTERASE 7
Descriptor:Cytosolic acyl coenzyme A thioester hydrolase
Authors:Busam, R., Lehtio, L., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Herman, M.D., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Persson, C., Structural Genomics Consortium (SGC)
Deposit date:2007-07-26
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human acyl-CoA thioesterase 7.
To be Published
2UVQ
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CRYSTAL STRUCTURE OF HUMAN URIDINE-CYTIDINE KINASE 1 IN COMPLEX WITH ADP
Descriptor:URIDINE-CYTIDINE KINASE 1, ADENOSINE-5'-DIPHOSPHATE
Authors:Kosinska, U., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E.P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Welin, M., Nordlund, P.
Deposit date:2007-03-13
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of Human Uridine-Cytidine Kinase 1
To be Published
2UW2
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CRYSTAL STRUCTURE OF HUMAN RIBONUCLEOTIDE REDUCTASE SUBUNIT R2
Descriptor:RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT, FE (III) ION
Authors:Welin, M., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Kotenyova, T., Magnusdottir, A., Moche, M., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Stenmark, P., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.
Deposit date:2007-03-16
Release date:2007-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of Human Ribonucleotide Reductase Subunit R2
To be Published
2UZ9
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HUMAN GUANINE DEAMINASE (GUAD) IN COMPLEX WITH ZINC AND ITS PRODUCT XANTHINE.
Descriptor:GUANINE DEAMINASE, ZINC ION, XANTHINE
Authors:Moche, M., Welin, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., van den berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2007-04-26
Release date:2007-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human Guanine Deaminase (Guad) in Complex with Zinc and its Product Xhantine
To be Published
2V30
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HUMAN OROTIDINE 5'-PHOSPHATE DECARBOXYLASE DOMAIN OF URIDINE MONOPHOSPATE SYNTHETASE (UMPS) IN COMPLEX WITH ITS PRODUCT UMP.
Descriptor:OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, URIDINE-5'-MONOPHOSPHATE
Authors:Moche, M., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2007-06-10
Release date:2007-07-24
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Crystal Structure of Human Orotidine 5'-Decarboxylase Domain of Human Uridine Monophosphate Synthetase (Umps)
To be Published
2V40
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HUMAN ADENYLOSUCCINATE SYNTHETASE ISOZYME 2 IN COMPLEX WITH GDP
Descriptor:ADENYLOSUCCINATE SYNTHETASE ISOZYME 2, GUANOSINE-5'-DIPHOSPHATE
Authors:Welin, M., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2007-06-27
Release date:2007-07-10
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Human Adenylosuccinate Synthetase Isozyme 2 in Complex with Gdp
To be Published
2VD6
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HUMAN ADENYLOSUCCINATE LYASE IN COMPLEX WITH ITS SUBSTRATE N6-(1,2- DICARBOXYETHYL)-AMP, AND ITS PRODUCTS AMP AND FUMARATE.
Descriptor:ADENYLOSUCCINATE LYASE, ADENOSINE MONOPHOSPHATE, FUMARIC ACID, ...
Authors:Stenmark, P., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2007-09-30
Release date:2007-10-23
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human Adenylosuccinate Lyase in Complex with its Substrate N6-(1,2-Dicarboxyethyl)-AMP, and its Products AMP and Fumarate.
To be Published
3F0W
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HUMAN NUMB-LIKE PROTEIN, PHOSPHOTYROSINE INTERACTION DOMAIN
Descriptor:Numb-like protein, SULFATE ION, CHLORIDE ION
Authors:Lehtio, L., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Bountra, C., D Busam, R., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2008-10-27
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human NUMB-like protein, phosphotyrosine interaction domain
To be Published
2RF5
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CRYSTAL STRUCTURE OF HUMAN TANKYRASE 1- CATALYTIC PARP DOMAIN
Descriptor:Tankyrase-1, ZINC ION, GLYCEROL
Authors:Lehtio, L., Karlberg, T., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Welin, M., Weigelt, J., Structural Genomics Consortium (SGC)
Deposit date:2007-09-28
Release date:2007-10-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Zinc binding catalytic domain of human tankyrase 1.
J.Mol.Biol., 379, 2008
3C49
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HUMAN POLY(ADP-RIBOSE) POLYMERASE 3, CATALYTIC FRAGMENT IN COMPLEX WITH AN INHIBITOR KU0058948
Descriptor:Poly(ADP-ribose) polymerase 3, 4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one
Authors:Lehtio, L., Karlberg, T., Arrowsmith, C.H., Berglund, H., Bountra, C., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Helleday, T., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., Van den Berg, S., Welin, M., Weigelt, J., Structural Genomics Consortium (SGC)
Deposit date:2008-01-29
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
J.Med.Chem., 52, 2009
3C4H
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HUMAN POLY(ADP-RIBOSE) POLYMERASE 3, CATALYTIC FRAGMENT IN COMPLEX WITH AN INHIBITOR DR2313
Descriptor:Poly(ADP-ribose) polymerase 3, 2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one, DIMETHYL SULFOXIDE
Authors:Lehtio, L., Collins, R., Arrowsmith, C.H., Berglund, H., Bountra, C., Busam, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., Van den Berg, S., Welin, M., Weigelt, J., Structural Genomics Consortium (SGC)
Deposit date:2008-01-30
Release date:2008-02-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
J.Med.Chem., 52, 2009
3CE0
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HUMAN POLY(ADP-RIBOSE) POLYMERASE 3, CATALYTIC FRAGMENT IN COMPLEX WITH AN INHIBITOR PJ34
Descriptor:Poly [ADP-ribose] polymerase 3, N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE
Authors:Lehtio, L., Karlberg, T., Arrowsmith, C.H., Berglund, H., Bountra, C., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., van den Berg, S., Welin, M., Weigelt, J., Structural Genomics Consortium (SGC)
Deposit date:2008-02-27
Release date:2008-03-11
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
J.Med.Chem., 52, 2009
3FHB
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HUMAN POLY(ADP-RIBOSE) POLYMERASE 3, CATALYTIC FRAGMENT IN COMPLEX WITH AN INHIBITOR 3-AMINOBENZOIC ACID
Descriptor:Poly [ADP-ribose] polymerase 3, 3-AMINOBENZOIC ACID
Authors:Lehtio, L., Karlberg, T., Arrowsmith, C.H., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Johansson, I., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Schueler, H., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2008-12-09
Release date:2009-01-06
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for inhibitor specificity in human poly(ADP-ribose) polymerase-3.
J.Med.Chem., 52, 2009
2FVZ
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HUMAN INOSITOL MONOPHOSPHOSPHATASE 2
Descriptor:Inositol monophosphatase 2
Authors:Ogg, D., Hallberg, B.M., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Hogbom, M., Holmberg-Schiavone, L., Kotenyova, T., Kursula, P., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Van Den Berg, S., Weigelt, J., Thorsell, A.G., Structural Genomics Consortium (SGC)
Deposit date:2006-01-31
Release date:2006-02-21
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of Human Inositol Monophosphatase 2
To be published
2G9N
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STRUCTURE OF THE DEAD DOMAIN OF HUMAN EUKARYOTIC INITIATION FACTOR 4A, EIF4A
Descriptor:Eukaryotic initiation factor 4A-I
Authors:Hogbom, M., Ogg, D., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)
Deposit date:2006-03-07
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010