Author results

6E31
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CRYSTAL STRUCTURE OF RIAM IN AN AUTOINHIBITED CONFIGURATION.
Descriptor:Rap1-interacting adapter molecule
Authors:Chang, Y.C., Su, W., Zhang, H., Huang, Q., Philips, M.R., Wu, J.
Deposit date:2018-07-12
Release date:2019-02-20
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
4Z4X
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CRYSTAL STRUCTURE OF MULTIDRUG RESISTANT HIV-1 PROTEASE CLINICAL ISOLATE PR20D25N WITH OPEN FLAP
Descriptor:Protease
Authors:Chang, Y.C., Shen, C.-H., Weber, I.T.
Deposit date:2015-04-02
Release date:2015-10-14
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Conformational variation of an extreme drug resistant mutant of HIV protease.
J.Mol.Graph.Model., 62, 2015
2B3Z
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CRYSTAL STRUCTURE OF A BIFUNCTIONAL DEAMINASE AND REDUCTASE INVOLVED IN RIBOFLAVIN BIOSYNTHESIS
Descriptor:Riboflavin biosynthesis protein ribD, ZINC ION
Authors:Chen, S.J., Chang, Y.C., Liaw, S.H.
Deposit date:2005-09-22
Release date:2005-11-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structure of a bifunctional deaminase and reductase involved in riboflavin biosynthesis
To be Published
2D5N
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CRYSTAL STRUCTURE OF A BIFUNCTIONAL DEAMINASE AND REDUCTASE INVOLVED IN RIBOFLAVIN BIOSYNTHESIS
Descriptor:Riboflavin biosynthesis protein ribD, ZINC ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Liaw, S.H., Chen, S.J., Chang, Y.C.
Deposit date:2005-11-02
Release date:2005-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Crystal structure of a bifunctional deaminase and reductase involved in riboflavin biosynthesis
To be Published
5ITJ
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THE STRUCTURE OF HISTONE-LIKE PROTEIN
Descriptor:AbrB family transcriptional regulator, SULFATE ION, TETRAETHYLENE GLYCOL
Authors:Lin, B.L., Chen, C.Y., Huang, C.H., Ko, T.P., Chiang, C.H., Lin, K.F., Chang, Y.C., Lin, P.Y., Tsai, H.H.G., Wang, A.H.J.
Deposit date:2016-03-17
Release date:2017-01-25
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA.
PLoS ONE, 12, 2017
5ITM
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THE STRUCTURE OF TRUNCATED HISTONE-LIKE PROTEIN
Descriptor:AbrB family transcriptional regulator
Authors:Lin, B.L., Chen, C.Y., Huang, C.H., Ko, T.P., Chiang, C.H., Lin, K.F., Chang, Y.C., Lin, P.Y., Tsai, H.H.G., Wang, A.H.J.
Deposit date:2016-03-17
Release date:2017-01-25
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA.
PLoS ONE, 12, 2017
6JCV
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CRYO-EM STRUCTURE OF SULFOLOBUS SOLFATARICUS KETOL-ACID REDUCTOISOMERASE (SSO-KARI) WITH MG2+ AT PH7.5
Descriptor:Putative ketol-acid reductoisomerase 2, MAGNESIUM ION
Authors:Chen, C.Y., Chang, Y.C., Lin, K.F., Huang, C.H., Lin, B.L., Ko, T.P., Hsieh, D.L., Tsai, M.D.
Deposit date:2019-01-30
Release date:2019-04-17
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J. Am. Chem. Soc., 2019
6JCW
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CRYO-EM STRUCTURE OF SULFOLOBUS SOLFATARICUS KETOL-ACID REDUCTOISOMERASE (SSO-KARI) WITH MG2+ AT PH8.5
Descriptor:ketol-acid reductoisomerase, MAGNESIUM ION
Authors:Chen, C.Y., Chang, Y.C., Lin, K.F., Huang, C.H., Lin, B.L., Ko, T.P., Hsieh, D.L., Tsai, M.D.
Deposit date:2019-01-30
Release date:2019-04-17
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J. Am. Chem. Soc., 2019
6JCZ
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CRYO-EM STRUCTURE OF SULFOLOBUS SOLFATARICUS KETOL-ACID REDUCTOISOMERASE (SSO-KARI) IN COMPLEX WITH MG2+, NADPH, AND CPD AT PH7.5
Descriptor:Putative ketol-acid reductoisomerase 2, MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Chen, C.Y., Chang, Y.C., Lin, K.F., Huang, C.H., Lin, B.L., Ko, T.P., Hsieh, D.L., Tsai, M.D.
Deposit date:2019-01-30
Release date:2019-04-17
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J. Am. Chem. Soc., 2019
6JD1
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CRYO-EM STRUCTURE OF SULFOLOBUS SOLFATARICUS KETOL-ACID REDUCTOISOMERASE (SSO-KARI) IN COMPLEX WITH MG2+, NADH, AND CPD AT PH7.5
Descriptor:Putative ketol-acid reductoisomerase 2, MAGNESIUM ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Chen, C.Y., Chang, Y.C., Lin, K.F., Huang, C.H., Lin, B.L., Ko, T.P., Hsieh, D.L., Tsai, M.D.
Deposit date:2019-01-30
Release date:2019-04-17
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J. Am. Chem. Soc., 2019
3VF5
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CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT I47V WITH NOVEL P1'-LIGANDS GRL-02031
Descriptor:Protease, SODIUM ION, CHLORIDE ION, ...
Authors:Yu, X.X., Wang, Y.F., Chang, Y.C.E., Weber, I.T.
Deposit date:2012-01-09
Release date:2012-11-21
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.
J.Med.Chem., 55, 2012
3VF7
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CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT L76V WITH NOVEL P1'-LIGANDS GRL-02031
Descriptor:protease, (3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl [(1S,2R)-1-benzyl-2-hydroxy-3-([(4-methoxyphenyl)sulfonyl]{[(2R)-5-oxopyrrolidin-2-yl]methyl}amino)propyl]carbamate, SODIUM ION, ...
Authors:Yu, X.X., Wang, Y.F., Chang, Y.C.E., Weber, I.T.
Deposit date:2012-01-09
Release date:2012-11-21
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.
J.Med.Chem., 55, 2012
3VFA
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CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT V82A WITH NOVEL P1'-LIGANDS GRL-02031
Descriptor:protease, (3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl [(1S,2R)-1-benzyl-2-hydroxy-3-([(4-methoxyphenyl)sulfonyl]{[(2R)-5-oxopyrrolidin-2-yl]methyl}amino)propyl]carbamate, SODIUM ION, ...
Authors:Yu, X.X., Wang, Y.F., Chang, Y.C.E., Weber, I.T.
Deposit date:2012-01-09
Release date:2012-11-21
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.
J.Med.Chem., 55, 2012
3VFB
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CRYSTAL STRUCTURE OF HIV-1 PROTEASE MUTANT N88D WITH NOVEL P1'-LIGANDS GRL-02031
Descriptor:protease, (3aS,5R,6aR)-hexahydro-2H-cyclopenta[b]furan-5-yl [(1S,2R)-1-benzyl-2-hydroxy-3-([(4-methoxyphenyl)sulfonyl]{[(2R)-5-oxopyrrolidin-2-yl]methyl}amino)propyl]carbamate, CHLORIDE ION, ...
Authors:Yu, X.X., Wang, Y.F., Chang, Y.C.E., Weber, I.T.
Deposit date:2012-01-09
Release date:2012-11-21
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring.
J.Med.Chem., 55, 2012
4GMV
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CRYSTAL STRUCTURE OF THE COILED-COIL, RA AND PH DOMAINS OF LAMELLIPODIN
Descriptor:Ras-associated and pleckstrin homology domains-containing protein 1
Authors:Chang, Y.C.E., Wu, J.
Deposit date:2012-08-16
Release date:2012-11-28
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.403 Å)
Cite:Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling.
Protein Cell, 4, 2013
4GN1
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CRYSTAL STRUCTURE OF THE RA AND PH DOMAINS OF LAMELLIPODIN
Descriptor:Ras-associated and pleckstrin homology domains-containing protein 1, MALONATE ION
Authors:Chang, Y.C.E., Wu, J.
Deposit date:2012-08-16
Release date:2012-11-28
Last modified:2013-03-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling.
Protein Cell, 4, 2013
4W8P
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CRYSTAL STRUCTURE OF RIAM TBS1 IN COMPLEX WITH TALIN R7R8 DOMAINS
Descriptor:Talin-1, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, 1,2-ETHANEDIOL
Authors:Chang, Y.C.E., Zhang, H., Wu, J.
Deposit date:2014-08-25
Release date:2014-12-03
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural and Mechanistic Insights into the Recruitment of Talin by RIAM in Integrin Signaling.
Structure, 22, 2014
5ZME
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NUCLEOTIDE-FREE FORM OF C. REINHARDTII ARSA1
Descriptor:ATPase ARSA1, PHOSPHATE ION
Authors:Lin, T.W., Hsiao, C.D., Chang, H.Y.
Deposit date:2018-04-03
Release date:2019-03-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.603 Å)
Cite:Structural analysis of chloroplast tail-anchored membrane protein recognition by ArsA1.
Plant J., 2019
5ZMF
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AMPPNP COMPLEX OF C. REINHARDTII ARSA1
Descriptor:ATPase ARSA1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION
Authors:Lin, T.W., Hsiao, C.D., Chang, H.Y.
Deposit date:2018-04-03
Release date:2019-03-20
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (3.556 Å)
Cite:Structural analysis of chloroplast tail-anchored membrane protein recognition by ArsA1.
Plant J., 2019
2ZUB
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LEFT HANDED RADA
Descriptor:DNA repair and recombination protein radA
Authors:Chang, Y.W., Ko, T.P., Wang, T.F., Wang, A.H.J.
Deposit date:2008-10-15
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity
Plos One, 4, 2009
2ZUC
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CRYSTAL STRUCTURE OF LEFT-HANDED RADA FILAMENT
Descriptor:DNA repair and recombination protein radA
Authors:Chang, Y.W., Ko, T.P., Wang, T.F., Wang, A.H.J.
Deposit date:2008-10-15
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity
Plos One, 4, 2009
2ZUD
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CRYSTAL STRUCTURE OF LEFT-HANDED RADA FILAMENT
Descriptor:DNA repair and recombination protein radA
Authors:Chang, Y.W., Ko, T.P., Wang, T.F., Wang, A.H.J.
Deposit date:2008-10-16
Release date:2009-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity
Plos One, 4, 2009
4EJT
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STAPHYLOCOCCUS EPIDERMIDIS TCAR IN COMPLEX WITH RNA
Descriptor:Transcriptional regulator TcaR, 5'-R(*AP*A)-3'
Authors:Chang, Y.M., Chen, C.K.-M., Wang, A.H.-J.
Deposit date:2012-04-07
Release date:2013-06-05
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional studies of ssDNA binding ability of MarR family protein TcaR from Staphylococcus epidermidis.
Plos One, 7, 2012
5XFT
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CRYSTAL STRUCTURE OF CHLAMYDOMONAS REINHARDTII DEHYDROASCORBATE REDUCTASE
Descriptor:Dehydroascorbate reductase
Authors:Chang, H.Y., Ko, T.P., Huang, K.F.
Deposit date:2017-04-11
Release date:2017-12-27
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Enzymatic characterization and crystal structure analysis of Chlamydomonas reinhardtii dehydroascorbate reductase and their implications for oxidative stress
Plant Physiol. Biochem., 120, 2017
6JC5
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CRYSTAL STRUCTURE OF THE BLUE FLUORESCENT PROTEIN WITH A LEU-LEU-GLY TRI-PEPTIDE CHROMOPHORE DERIVED FROM THE PURPLE CHROMOPROTEIN OF STICHODACTYLA HADDONI
Descriptor:shBFP
Authors:Ko, T.P., Huang, K.F., Chang, H.Y.
Deposit date:2019-01-28
Release date:2019-03-20
Method:X-RAY DIFFRACTION (2.051 Å)
Cite:Crystal structure of the blue fluorescent protein with a Leu-Leu-Gly tri-peptide chromophore derived from the purple chromoprotein of Stichodactyla haddoni.
Int. J. Biol. Macromol., 130, 2019
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