4Z4X

Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20D25N with Open Flap

Summary for 4Z4X

• Entry DOI: 10.2210/pdb4z4x/pdb
• Related: 4Z50
• Descriptor: Protease (2 entities in total)
• Functional Keywords: hiv-1 protease, hydrolase
• Biological source: Human immunodeficiency virus 1
• Total number of polymer chains: 2
• Total formula weight: 21531.12

Authors

Chang, Y.C.,Shen, C.-H.,Weber, I.T. (deposition date: 2015-04-02, release date: 2015-10-14, Last modification date: 2023-09-27)

• Primary citation: Shen, C.H.,Chang, Y.C.,Agniswamy, J.,Harrison, R.W.,Weber, I.T.; Conformational variation of an extreme drug resistant mutant of HIV protease.; J.Mol.Graph.Model., 62:87-96, 2015; PubMed: 26397743; DOI: 10.1016/j.jmgm.2015.09.006

Experimental method

X-RAY DIFFRACTION (1.75 Å)