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2JQF
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FULL LENGTH LEADER PROTEASE OF FOOT AND MOUTH DISEASE VIRUS C51A MUTANT
Descriptor:Genome polyprotein
Authors:Cencic, R., Mayer, C., Juliano, M.A., Juliano, L., Konrat, R., Kontaxis, G., Skern, T.
Deposit date:2007-06-01
Release date:2007-07-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Investigating the Substrate Specificity and Oligomerisation of the Leader Protease of Foot and Mouth Disease Virus using NMR
J.Mol.Biol., 373, 2007
2JQG
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LEADER PROTEASE
Descriptor:Genome polyprotein
Authors:Cencic, R., Mayer, C., Juliano, M.A., Juliano, L., Konrat, R., Kontaxis, G., Skern, T.
Deposit date:2007-06-01
Release date:2007-07-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Investigating the Substrate Specificity and Oligomerisation of the Leader Protease of Foot and Mouth Disease Virus using NMR
J.Mol.Biol., 373, 2007
4QBB
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STRUCTURE OF THE FOOT-AND-MOUTH DISEASE VIRUS LEADER PROTEINASE IN COMPLEX WITH INHIBITOR (N~2~-[(3S)-4-({(2R)-1-[(4-CARBAMIMIDAMIDOBUTYL)AMINO]-4-METHYL-1-OXOPENTAN-2-YL}AMINO)-3-HYDROXY-4-OXOBUTANOYL]-L-ARGINYL-L-PROLINAMIDE)
Descriptor:Leader protease, POTASSIUM ION, N~2~-[(3S)-4-({(2R)-1-[(4-carbamimidamidobutyl)amino]-4-methyl-1-oxopentan-2-yl}amino)-3-hydroxy-4-oxobutanoyl]-L-arginyl-L-prolinamide, ...
Authors:Grishkovskaya, I., Steinberger, J., Cencic, R., Juliano, M.A., Juliano, L., Skern, T.
Deposit date:2014-05-07
Release date:2014-11-05
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Foot-and-mouth disease virus leader proteinase: Structural insights into the mechanism of intermolecular cleavage.
Virology, 468-470C, 2014
5TBW
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CRYSTAL STRUCTURE OF CHLOROLISSOCLIMIDE BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Konst, Z.A., Szklarski, A.R., Pellegrino, S., Michalak, S.E., Meyer, M., Zanette, C., Cencic, R., Nam, S., Horne, D.A., Pelletier, J., Mobley, D.L., Yusupova, G., Yusupov, M., Vanderwal, C.D.
Deposit date:2016-09-13
Release date:2017-07-26
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides.
Nat Chem, 9, 2017
5UDI
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IFIT1 MONOMERIC MUTANT (L457E/L464E) WITH M7GPPP-AAAA (SYN AND ANTI CONFORMATIONS OF CAP)
Descriptor:Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), TRIETHYLENE GLYCOL, ...
Authors:Abbas, Y.M., Martinez-Montero, S., Damha, M.J., Nagar, B.
Deposit date:2016-12-27
Release date:2017-03-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDJ
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IFIT1 MONOMERIC MUTANT (L457E/L464E) WITH GPPP-AAAA
Descriptor:Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(G3A))-R(P*AP*AP*A)-3'), TRIETHYLENE GLYCOL, ...
Authors:Abbas, Y.M., Martinez-Montero, S., Damha, M.J., Nagar, B.
Deposit date:2016-12-27
Release date:2017-03-01
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDK
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IFIT1 MONOMERIC MUTANT (L457E/L464E) WITH PPP-AAAA
Descriptor:Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(ATP))-R(P*AP*AP*A)-3'), TRIETHYLENE GLYCOL, ...
Authors:Abbas, Y.M., Martinez-Montero, S., Damha, M.J., Nagar, B.
Deposit date:2016-12-27
Release date:2017-03-01
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UDL
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IFIT1 N216A MONOMERIC MUTANT (L457E/L464E) WITH M7GPPP-AAAA (ANTI CONFORMATION OF CAP)
Descriptor:Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3'), TRIETHYLENE GLYCOL, ...
Authors:Abbas, Y.M., Martinez-Montero, S., Damha, M.J., Nagar, B.
Deposit date:2016-12-27
Release date:2017-03-01
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2'-O methylations.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W5H
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HUMAN IFIT1 DIMER WITH M7GPPP-AAAA
Descriptor:Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(GTA))-R(P*AP*AP*A)-3')
Authors:Abbas, Y.M., Martinez-Montero, S., Damha, M.J., Nagar, B.
Deposit date:2017-06-15
Release date:2017-07-19
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published
5W5I
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HUMAN IFIT1 DIMER WITH PPP-AAAA
Descriptor:Interferon-induced protein with tetratricopeptide repeats 1, RNA (5'-D(*(ATP))-R(P*AP*AP*A)-3')
Authors:Abbas, Y.M., Martinez-Montero, S., Damha, M.J., Nagar, B.
Deposit date:2017-06-15
Release date:2017-06-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural insights into IFIT1 dimerization and conformational changes associated with mRNA binding
To Be Published