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5FLX
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BU of 5flx by Molmil
Mammalian 40S HCV-IRES complex
Descriptor: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
Authors:Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T.
Deposit date:2015-10-28
Release date:2015-12-23
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
5AJ0
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BU of 5aj0 by Molmil
Cryo electron microscopy of actively translating human polysomes (POST state).
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T.
Deposit date:2015-02-19
Release date:2015-05-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Snapshots of Actively Translating Human Ribosomes
Cell(Cambridge,Mass.), 161, 2015
4UJD
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BU of 4ujd by Molmil
mammalian 80S HCV-IRES initiation complex with eIF5B PRE-like state
Descriptor: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S RIBOSOMAL PROTEIN ES1, ...
Authors:Yamamoto, H, Unbehaun, A, Loerke, J, Behrmann, E, Marianne, C, Burger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2014-06-18
Release date:2014-07-30
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Structure of the Mammalian 80S Initiation Complex with Eif5B on Hcv Ires
Nat.Struct.Mol.Biol., 21, 2014
4UJC
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BU of 4ujc by Molmil
mammalian 80S HCV-IRES initiation complex with eIF5B POST-like state
Descriptor: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES1, ...
Authors:Yamamoto, H, Unbehaun, A, Loerke, J, Behrmann, E, Marianne, C, Burger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2014-06-18
Release date:2014-07-30
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Structure of the Mammalian 80S Initiation Complex with Initiation Factor 5B on Hcv-Ires RNA.
Nat.Struct.Mol.Biol., 21, 2014
6HHC
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BU of 6hhc by Molmil
Allosteric Inhibition as a new mode of Action for BAY 1213790, a Neutralizing Antibody Targeting the Activated form of Coagulation Factor XI
Descriptor: Coagulation factor XI, DIMETHYL SULFOXIDE, FXIA ANTIBODY FAB HEAVY CHAIN, ...
Authors:Schaefer, M, Buchmueller, A, Dittmer, F, Strassburger, J, Wilmen, A.
Deposit date:2018-08-27
Release date:2019-09-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Allosteric Inhibition as a New Mode of Action for BAY 1213790, a Neutralizing Antibody Targeting the Activated Form of Coagulation Factor XI.
J.Mol.Biol., 431, 2019
5MS0
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BU of 5ms0 by Molmil
pseudo-atomic model of the RNA polymerase lambda-based antitermination complex solved by cryo-EM
Descriptor: 30S ribosomal protein S10, Antitermination protein N, DNA-directed RNA polymerase subunit alpha, ...
Authors:Said, N, Krupp, F.
Deposit date:2016-12-29
Release date:2017-05-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
7PIU
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BU of 7piu by Molmil
Cryo-EM structure of the agonist setmelanotide bound to the active melanocortin-4 receptor (MC4R) in complex with the heterotrimeric Gs protein at 2.6 A resolution.
Descriptor: CALCIUM ION, Camelid antibody fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P.
Deposit date:2021-08-23
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide.
Cell Res., 31, 2021
7PIV
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BU of 7piv by Molmil
Active Melanocortin-4 receptor (MC4R)- Gs protein complex bound to agonist NDP-alpha-MSH at 2.86 A resolution.
Descriptor: CALCIUM ION, Camelid antibody VHH fragment - nanobody 35, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Heyder, N.A, Schmidt, A, Kleinau, G, Hilal, T, Scheerer, P.
Deposit date:2021-08-23
Release date:2021-11-17
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structures of active melanocortin-4 receptor-Gs-protein complexes with NDP-alpha-MSH and setmelanotide.
Cell Res., 31, 2021
8RCT
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BU of 8rct by Molmil
Escherichia coli paused disome complex (Rotated disome interface class 2)
Descriptor: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
Authors:Fluegel, T, Schacherl, M.
Deposit date:2023-12-07
Release date:2024-03-06
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (5.32 Å)
Cite:Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
8RCM
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BU of 8rcm by Molmil
Escherichia coli paused disome complex (Non-rotated disome interface class 2)
Descriptor: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
Authors:Fluegel, T, Schacherl, M.
Deposit date:2023-12-06
Release date:2024-03-06
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
8RCS
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BU of 8rcs by Molmil
Escherichia coli paused disome complex (Rotated disome interface class 1)
Descriptor: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
Authors:Fluegel, T, Schacherl, M.
Deposit date:2023-12-07
Release date:2024-03-06
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (4.46 Å)
Cite:Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
8R3V
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BU of 8r3v by Molmil
Escherichia coli paused disome complex (non-rotated disome interface)
Descriptor: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
Authors:Fluegel, T, Schacherl, M.
Deposit date:2023-11-10
Release date:2024-03-06
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
8RCL
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BU of 8rcl by Molmil
Escherichia coli paused disome complex (Non-rotated disome interface class 1)
Descriptor: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
Authors:Fluegel, T, Schacherl, M.
Deposit date:2023-12-06
Release date:2024-03-13
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
3JCJ
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BU of 3jcj by Molmil
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2015-12-18
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
3JCN
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BU of 3jcn by Molmil
Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association: Initiation Complex I
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2016-01-04
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
5M1J
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BU of 5m1j by Molmil
Nonstop ribosomal complex bound with Dom34 and Hbs1
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Hilal, T, Yamamoto, H, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T.
Deposit date:2016-10-07
Release date:2017-01-18
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution.
Nat Commun, 7, 2016
5LM7
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BU of 5lm7 by Molmil
Crystal structure of the lambda N-Nus factor complex
Descriptor: 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ...
Authors:Said, N, Santos, K, Weber, G, Wahl, M.C.
Deposit date:2016-07-29
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
5LM9
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BU of 5lm9 by Molmil
Structure of E. coli NusA
Descriptor: MAGNESIUM ION, SULFATE ION, Transcription termination/antitermination protein NusA
Authors:Said, N, Weber, G, Santos, K, Wahl, M.C.
Deposit date:2016-07-29
Release date:2017-04-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.143 Å)
Cite:Structural basis for lambda N-dependent processive transcription antitermination.
Nat Microbiol, 2, 2017
8PKL
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BU of 8pkl by Molmil
Escherichia coli paused disome complex (leading 70S non-rotated closed PRE state)
Descriptor: 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 23S ribosomal RNA, ...
Authors:Fluegel, T, Schacherl, M.
Deposit date:2023-06-26
Release date:2024-03-06
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
8PEG
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BU of 8peg by Molmil
Escherichia coli paused disome complex (queueing 70S non-rotated closed PRE state)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ...
Authors:Fluegel, T, Schacherl, M.
Deposit date:2023-06-13
Release date:2024-03-06
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Transient disome complex formation in native polysomes during ongoing protein synthesis captured by cryo-EM.
Nat Commun, 15, 2024
8TYE
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BU of 8tye by Molmil
Lassa GPC (strain Josiah) bound to rabbit polyclonal fusion-peptide-targeting antibody FP-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Perrett, H.R, Brouwer, P.J.M, Ward, A.B.
Deposit date:2023-08-25
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses
To Be Published
8TYC
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BU of 8tyc by Molmil
Lassa GPC (strain Josiah) bound to rabbit polyclonal base-targeting antibody Base-1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Perrett, H.R, Brouwer, P.J.M, Ward, A.B.
Deposit date:2023-08-24
Release date:2024-09-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mapping of vaccine-induced humoral responses to the Lassa virus glycoprotein reveals off-target and immunodominant responses
To Be Published
8C93
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BU of 8c93 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.17 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C99
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BU of 8c99 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L15, ...
Authors:Nikolay, R, Qin, B, Lauer, S.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023
8C96
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BU of 8c96 by Molmil
Cryo-EM captures early ribosome assembly in action
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Lauer, S, Nikolay, R, Qin, B.
Deposit date:2023-01-21
Release date:2023-04-05
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.43 Å)
Cite:Cryo-EM captures early ribosome assembly in action.
Nat Commun, 14, 2023

 

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