Author results

1MJT
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CRYSTAL STRUCTURE OF SANOS, A BACTERIAL NITRIC OXIDE SYNTHASE OXYGENASE PROTEIN, IN COMPLEX WITH NAD+ AND SEITU
Descriptor:NITRIC-OXIDE SYNTHASE HOMOLOG, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Bird, L.E., Ren, J., Stammers, D.K.
Deposit date:2002-08-28
Release date:2003-01-07
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of SANOS, a Bacterial Nitric Oxide Synthase Oxygenase Protein from Staphylococcus aureus
Structure, 10, 2002
1OSN
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CRYSTAL STRUCTURE OF VARICELLA ZOSTER VIRUS THYMIDINE KINASE IN COMPLEX WITH BVDU-MP AND ADP
Descriptor:Thymidine kinase, ADENOSINE-5'-DIPHOSPHATE, (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE-5'-MONOPHOSPHATE
Authors:Bird, L.E., Ren, J., Wright, A., Leslie, K.D., Degreve, B., Balzarini, J., Stammers, D.K.
Deposit date:2003-03-20
Release date:2003-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of varicella zoster virus thymidine kinase
J.Biol.Chem., 278, 2003
3NAR
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CRYSTAL STRUCTURE OF ZHX1 HD4 (ZINC-FINGERS AND HOMEOBOXES PROTEIN 1, HOMEODOMAIN 4)
Descriptor:Zinc fingers and homeoboxes protein 1, SULFATE ION
Authors:Ren, J., Bird, L.E., Owens, R.J., Stammers, D.K., Oxford Protein Production Facility (OPPF)
Deposit date:2010-06-02
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains
Bmc Struct.Biol., 10, 2010
3NAU
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CRYSTAL STRUCTURE OF ZHX2 HD2 (ZINC-FINGERS AND HOMEOBOXES PROTEIN 2, HOMEODOMAIN 2)
Descriptor:Zinc fingers and homeoboxes protein 2, SULFATE ION
Authors:Ren, J., Bird, L.E., Owens, R.J., Stammers, D.K., Oxford Protein Production Facility (OPPF)
Deposit date:2010-06-02
Release date:2010-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains
Bmc Struct.Biol., 10, 2010
1EP4
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH S-1153
Descriptor:HIV-1 REVERSE TRANSCRIPTASE, 5-(3,5-DICHLOROPHENYL)THIO-4-ISOPROPYL-1-(PYRIDIN-4-YL-METHYL)-1H-IMIDAZOL-2-YL-METHYL CARBAMATE
Authors:Ren, J., Nichols, C., Bird, L.E., Fujiwara, T., Suginoto, H., Stuart, D.I., Stammers, D.K.
Deposit date:2000-03-27
Release date:2000-09-27
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding.
J.Biol.Chem., 275, 2000
1MU2
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CRYSTAL STRUCTURE OF HIV-2 REVERSE TRANSCRIPTASE
Descriptor:HIV-2 RT, SULFATE ION, GLYCEROL
Authors:Ren, J., Bird, L.E., Chamberlain, P.P., Stewart-Jones, G.B., Stuart, D.I., Stammers, D.K.
Deposit date:2002-09-23
Release date:2002-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors
Proc.Natl.Acad.Sci.USA, 99, 2002
1A0P
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SITE-SPECIFIC RECOMBINASE, XERD
Descriptor:SITE-SPECIFIC RECOMBINASE XERD
Authors:Subramanya, H.S., Arciszewska, L.K., Baker, R.A., Bird, L.E., Sherratt, D.J., Wigley, D.B.
Deposit date:1997-12-05
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the site-specific recombinase, XerD.
EMBO J., 16, 1997
1DTQ
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-1 (PETT131A94)
Descriptor:HIV-1 RT A-CHAIN, HIV-1 RT B-CHAIN, N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-NITRILOMETHYL-PYRIDYL]-THIOUREA
Authors:Ren, J., Diprose, J., Warren, J., Esnouf, R.M., Bird, L.E., Ikemizu, S., Slater, M., Milton, J., Balzarini, J., Stuart, D.I., Stammers, D.K.
Deposit date:2000-01-13
Release date:2000-03-20
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
J.Biol.Chem., 275, 2000
1DTT
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CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH PETT-2 (PETT130A94)
Descriptor:HIV-1 RT A-CHAIN, HIV-1 RT B-CHAIN, N-[[3-FLUORO-4-ETHOXY-PYRID-2-YL]ETHYL]-N'-[5-CHLORO-PYRIDYL]-THIOUREA
Authors:Ren, J., Diprose, J., Warren, J., Esnouf, R.M., Bird, L.E., Ikemizu, S., Slater, M., Milton, J., Balzarini, J., Stuart, D.I., Stammers, D.K.
Deposit date:2000-01-13
Release date:2000-04-02
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (3 Å)
Cite:Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
J.Biol.Chem., 275, 2000
1PJR
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STRUCTURE OF DNA HELICASE
Descriptor:PCRA
Authors:Subramanya, H.S., Bird, L.E., Brannigan, J.A., Wigley, D.B.
Deposit date:1996-10-11
Release date:1997-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a DExx box DNA helicase.
Nature, 384, 1996
2BKA
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CC3(TIP30)CRYSTAL STRUCTURE
Descriptor:TAT-INTERACTING PROTEIN TIP30, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ...
Authors:El Omari, K., Bird, L.E., Nichols, C.E., Ren, J., Stammers, D.K.
Deposit date:2005-02-14
Release date:2005-02-21
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of Cc3 (Tip30): Implications for its Role as a Tumor Suppressor
J.Biol.Chem., 280, 2005
2C5U
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T4 RNA LIGASE (RNL1) CRYSTAL STRUCTURE
Descriptor:RNA LIGASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, CALCIUM ION, ...
Authors:El Omari, K., Ren, J., Bird, L.E., Bona, M.K., Klarmann, G., LeGrice, S.F.J., Stammers, D.K.
Deposit date:2005-11-01
Release date:2005-11-04
Last modified:2012-09-12
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Molecular Architecture and Ligand Recognition Determinants for T4 RNA Ligase
J.Biol.Chem., 281, 2006
2Q5H
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CRYSTAL STRUCTURE OF APO-WILDTYPE GLYCYL-TRNA SYNTHETASE
Descriptor:Glycyl-tRNA synthetase
Authors:Cader, M.Z., Ren, J., James, P.A., Bird, L.E., Talbot, K., Stammers, D.K., Oxford Protein Production Facility (OPPF)
Deposit date:2007-06-01
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy.
Febs Lett., 581, 2007
2Q5I
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CRYSTAL STRUCTURE OF APO S581L GLYCYL-TRNA SYNTHETASE MUTANT
Descriptor:Glycyl-tRNA synthetase, SULFATE ION
Authors:Cader, M.Z., Ren, J., James, P.A., Bird, L.E., Talbot, K., Stammers, D.K., Oxford Protein Production Facility (OPPF)
Deposit date:2007-06-01
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy.
Febs Lett., 581, 2007
4BBK
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STRUCTURAL AND FUNCTIONAL CHARACTERISATION OF THE KINDLIN-1 PLECKSTRIN HOMOLOGY DOMAIN
Descriptor:FERMITIN FAMILY HOMOLOG 1, GLYCEROL
Authors:Yates, L.A., Lumb, C.N., Brahme, N.N., Zalyte, R., Bird, L.E., De Colibus, L., Owens, R.J., Calderwood, D.A., Sansom, M.S.P., Gilbert, R.J.C.
Deposit date:2012-09-25
Release date:2012-11-14
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain
J.Biol.Chem., 287, 2012
4GMK
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CRYSTAL STRUCTURE OF RIBOSE 5-PHOSPHATE ISOMERASE FROM THE PROBIOTIC BACTERIUM LACTOBACILLUS SALIVARIUS UCC118
Descriptor:Ribose-5-phosphate isomerase A, PHOSPHATE ION, POTASSIUM ION
Authors:Lobley, C.M.C., Aller, P., Douangamath, A., Reddivari, Y., Bumann, M., Bird, L.E., Brandao-Neto, J., Owens, R.J., O'Toole, P.W., Walsh, M.A.
Deposit date:2012-08-16
Release date:2012-08-29
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structure of ribose 5-phosphate isomerase from the probiotic bacterium Lactobacillus salivarius UCC118.
Acta Crystallogr.,Sect.F, 68, 2012
5A9D
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF PEPT1
Descriptor:SOLUTE CARRIER FAMILY 15 MEMBER 1, GLYCEROL
Authors:Beale, J.H., Bird, L.E., Owens, R.J., Newstead, S.
Deposit date:2015-07-20
Release date:2015-09-09
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of the Extracellular Domain from Pept1 and Pept2 Provide Novel Insights Into Mammalian Peptide Transport
Structure, 23, 2015
5ANQ
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INHIBITORS OF JUMONJIC DOMAIN-CONTAINING HISTONE DEMETHYLASES
Descriptor:LYSINE-SPECIFIC DEMETHYLASE 4A, 2-{2-[(pyridin-3-ylmethyl)amino]pyrimidin-4-yl}pyridine-4-carboxylic acid, FE (II) ION, ...
Authors:Roatsch, M., Robaa, D., Pippel, M., Nettleship, J.E., Reddivari, Y., Bird, L.E., Hoffmann, I., Franz, H., Owens, R.J., Schuele, R., Flaig, R., Sippl, W., Jung, M.
Deposit date:2015-09-07
Release date:2016-03-23
Last modified:2016-09-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substituted 2-(2-Aminopyrimidin-4-Yl)Pyridine-4-Carboxylates as Potent Inhibitors of Jumonjic Domain-Containing Histone Demethylases.
Fut.Med.Chem., 8, 2016
5EYV
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CRYSTAL STRUCTURE OF ADENYLOSUCCINATE LYASE FROM SCHISTOSOMA MANSONI IN APO FORM.
Descriptor:Adenylosuccinate lyase
Authors:Romanello, L., Torini, J.R., Bird, L.E., Nettleship, J.E., Owens, R.J., Reddivari, Y., Brandao-Neto, J., Pereira, H.M.
Deposit date:2015-11-25
Release date:2016-11-30
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
Mol. Biochem. Parasitol., 214, 2017
5IOL
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CRYSTAL STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE FROM SCHISTOSOMA MANSONI
Descriptor:Nucleoside diphosphate kinase
Authors:Torini, J.R.S., Romanello, L., Bird, L.E., Nettleship, J.E., Owens, R.J., Aller, P., DeMarco, R., Brandao-Neto, J., Pereira, H.M.
Deposit date:2016-03-08
Release date:2017-03-08
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.741 Å)
Cite:Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs.
Mol.Biochem.Parasitol., 2019
5IOM
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CRYSTAL STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE FROM SCHISTOSOMA MANSONI IS SPACE GROUP P6322
Descriptor:Nucleoside diphosphate kinase
Authors:Torini, J.R.S., Romanello, L., Bird, L.E., Nettleship, J.E., Owens, R.J., Aller, P., DeMarco, R., Brandao-Neto, J., Pereira, H.M.
Deposit date:2016-03-08
Release date:2017-08-09
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs.
Mol.Biochem.Parasitol., 2019
5IPF
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CRYSTAL STRUCTURE OF HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE FROM SCHISTOSOMA MANSONI IN COMPLEX WITH IMP
Descriptor:Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), INOSINIC ACID
Authors:Romanello, L., Torini, J.R.S., Bird, L.E., Nettleship, J.E., Owens, R.J., DeMarco, R., Pereira, H.M., Brandao-Neto, J.
Deposit date:2016-03-09
Release date:2017-03-15
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:In vitro and in vivo characterization of the multiple isoforms of Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferases.
Mol. Biochem. Parasitol., 229, 2019
5KK8
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CRYSTAL STRUCTURE OF NUCLEOSIDE DIPHOSPHATE KINASE FROM SCHISTOSOMA MANSONI IN COMPLEX WITH ADP
Descriptor:Nucleoside diphosphate kinase, ADENOSINE-5'-DIPHOSPHATE
Authors:Torini, J.R.S., Romanello, L., Bird, L.E., Nettleship, J.E., Owens, R.J., Aller, P., DeMarco, R., Brandao-Neto, J., Pereira, H.M.
Deposit date:2016-06-21
Release date:2017-06-21
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Characterization of a Schistosoma mansoni NDPK expressed in sexual and digestive organs.
Mol.Biochem.Parasitol., 2019
1JKH
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CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DMP-266(EFAVIRENZ)
Descriptor:HIV-1 RT, A-CHAIN, B-CHAIN, ...
Authors:Ren, J., Nichols, C., Bird, L., Chamberlain, P., Weaver, K., Short, S., Stuart, D.I., Stammers, D.K.
Deposit date:2001-07-12
Release date:2001-10-03
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
J.Mol.Biol., 312, 2001
1JLA
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CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH TNK-651
Descriptor:HIV-1 RT A-chain, HIV-1 RT B-chain, 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL
Authors:Ren, J., Nichols, C., Bird, L., Chamberlain, P., Weaver, K., Short, S., Stuart, D.I., Stammers, D.K.
Deposit date:2001-07-16
Release date:2001-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
J.Mol.Biol., 312, 2001
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170383
PDB entries from 2020-10-28