5IPF
Crystal structure of Hypoxanthine-guanine phosphoribosyltransferase from Schistosoma mansoni in complex with IMP
Summary for 5IPF
| Entry DOI | 10.2210/pdb5ipf/pdb |
| Descriptor | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), INOSINIC ACID (3 entities in total) |
| Functional Keywords | hypoxanthine-guanine phosphoribosyltransferase, enzyme, transferase |
| Biological source | Schistosoma mansoni (Blood fluke) |
| Total number of polymer chains | 4 |
| Total formula weight | 114334.93 |
| Authors | Romanello, L.,Torini, J.R.S.,Bird, L.E.,Nettleship, J.E.,Owens, R.J.,DeMarco, R.,Pereira, H.M.,Brandao-Neto, J. (deposition date: 2016-03-09, release date: 2017-03-15, Last modification date: 2023-09-27) |
| Primary citation | Romanello, L.,Zeraik, A.E.,de Freitas Fernandes, A.,Torini, J.R.,Bird, L.E.,Nettleship, J.E.,Rada, H.,Reddivari, Y.,Owens, R.J.,Serrao, V.H.B.,DeMarco, R.,Brandao-Neto, J.,Pereira, H.D. In vitro and in vivo characterization of the multiple isoforms of Schistosoma mansoni hypoxanthine-guanine phosphoribosyltransferases. Mol. Biochem. Parasitol., 229:24-34, 2019 Cited by PubMed: 30772423DOI: 10.1016/j.molbiopara.2019.02.005 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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