2Q5I
Crystal structure of apo S581L Glycyl-tRNA synthetase mutant
Summary for 2Q5I
Entry DOI | 10.2210/pdb2q5i/pdb |
Related | 2Q5H |
Descriptor | Glycyl-tRNA synthetase, SULFATE ION (3 entities in total) |
Functional Keywords | aminoacyl-trna synthetase, atp-binding, structural genomics, glycyl-trna synthetase, oxford protein production facility, oppf, ligase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P41250 |
Total number of polymer chains | 1 |
Total formula weight | 78776.82 |
Authors | Cader, M.Z.,Ren, J.,James, P.A.,Bird, L.E.,Talbot, K.,Stammers, D.K.,Oxford Protein Production Facility (OPPF) (deposition date: 2007-06-01, release date: 2007-06-19, Last modification date: 2023-08-30) |
Primary citation | Cader, M.Z.,Ren, J.,James, P.A.,Bird, L.E.,Talbot, K.,Stammers, D.K. Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy. Febs Lett., 581:2959-2964, 2007 Cited by PubMed: 17544401DOI: 10.1016/j.febslet.2007.05.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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