7OG0

Nontypeable Haemophillus influenzae SapA in open and closed conformations, in complex with double stranded RNA

Summary for 7OG0

• Entry DOI: 10.2210/pdb7og0/pdb
• Related: 6HHL 6HJI
• Descriptor: ABC-type transport system, periplasmic component, involved in antimicrobial peptide resistance, RNA (5'-R(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), CALCIUM ION, ... (4 entities in total)
• Functional Keywords: nthi, rna binding, peptide binding, substrate binding protein, peptide binding protein
• Biological source: Haemophilus influenzae (strain 86-028NP); More
• Total number of polymer chains: 4
• Total formula weight: 131440.99

Authors

Lukacik, P.,Owen, C.D.,Nettleship, J.E.,Bird, L.E.,Owens, R.J.,Walsh, M.A. (deposition date: 2021-05-05, release date: 2021-10-27, Last modification date: 2024-01-31)

• Primary citation: Lukacik, P.,Owen, C.D.,Harris, G.,Bolla, J.R.,Picaud, S.,Alibay, I.,Nettleship, J.E.,Bird, L.E.,Owens, R.J.,Biggin, P.C.,Filippakopoulos, P.,Robinson, C.V.,Walsh, M.A.; The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.; Plos One, 16:e0256070-e0256070, 2021; PubMed: 34653190; DOI: 10.1371/journal.pone.0256070

Experimental method

X-RAY DIFFRACTION (2.61 Å)