5FN2 | | CRYO-EM STRUCTURE OF GAMMA SECRETASE IN COMPLEX WITH A DRUG DAPT | | Descriptor: | Nicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ... | | Authors: | Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W. | | Deposit date: | 2015-11-10 | | Release date: | 2015-12-16 | | Last modified: | 2019-09-04 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
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5FN3 | | CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 1 OF THE APO- STATE ENSEMBLE | | Descriptor: | Nicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ... | | Authors: | Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W. | | Deposit date: | 2015-11-10 | | Release date: | 2015-12-16 | | Last modified: | 2019-09-11 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
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5FN4 | | CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 2 OF THE APO- STATE ENSEMBLE | | Descriptor: | Nicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ... | | Authors: | Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W. | | Deposit date: | 2015-11-10 | | Release date: | 2015-12-16 | | Last modified: | 2019-09-11 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
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5FN5 | | CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 3 OF THE APO- STATE ENSEMBLE | | Descriptor: | Nicastrin, Presenilin-1, Gamma-secretase subunit APH-1A, ... | | Authors: | Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W. | | Deposit date: | 2015-11-10 | | Release date: | 2015-12-16 | | Last modified: | 2019-09-11 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
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5GKY | | STRUCTURE OF RYR1 IN A CLOSED STATE (C1 CONFORMER) | | Descriptor: | Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION | | Authors: | Bai, X.C., Yan, Z., Wu, J.P., Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2019-10-16 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
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5GKZ | | STRUCTURE OF RYR1 IN A CLOSED STATE (C3 CONFORMER) | | Descriptor: | Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION | | Authors: | Bai, X.C., Yan, Z., Wu, J.P., Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2019-10-16 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
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5GL0 | | STRUCTURE OF RYR1 IN A CLOSED STATE (C4 CONFORMER) | | Descriptor: | Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION | | Authors: | Bai, X.C., Yan, Z., Wu, J.P., Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2019-10-16 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
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5GL1 | | STRUCTURE OF RYR1 IN AN OPEN STATE | | Descriptor: | Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION | | Authors: | Bai, X.C., Yan, Z., Wu, J.P., Yan, N. | | Deposit date: | 2016-07-07 | | Release date: | 2016-08-24 | | Last modified: | 2019-10-16 | | Method: | ELECTRON MICROSCOPY (5.7 Å) | | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
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5GAM | | FOOT REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP | | Descriptor: | U5 snRNA, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ... | | Authors: | Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-02-03 | | Last modified: | 2019-10-02 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
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5GAN | | THE OVERALL STRUCTURE OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP AT 3.7 ANGSTROM | | Descriptor: | U4 snRNA, U6 snRNA, Pre-mRNA-splicing factor 8, ... | | Authors: | Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-01-27 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
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5GAO | | HEAD REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP | | Descriptor: | Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, ... | | Authors: | Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-01-27 | | Last modified: | 2019-10-02 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
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3J6B | | STRUCTURE OF THE YEAST MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT | | Descriptor: | 21S ribosomal RNA, 54S ribosomal protein RML2, mitochondrial, ... | | Authors: | Amunts, A., Brown, A., Bai, X.C., Llacer, J.L., Hussain, T., Emsley, P., Long, F., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V. | | Deposit date: | 2014-01-22 | | Release date: | 2014-04-09 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
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3J79 | | CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTI-PROTOZOAN DRUG EMETINE, LARGE SUBUNIT | | Descriptor: | 28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Wong, W., Bai, X.C., Brown, A., Fernandez, I.S., Hanssen, E., Condron, M., Tan, Y.H., Baum, J., Scheres, S.H.W. | | Deposit date: | 2014-06-02 | | Release date: | 2014-07-16 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
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3J7A | | CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTI-PROTOZOAN DRUG EMETINE, SMALL SUBUNIT | | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein uS2, ... | | Authors: | Wong, W., Bai, X.C., Brown, A., Fernandez, I.S., Hanssen, E., Condron, M., Tan, Y.H., Baum, J., Scheres, S.H.W. | | Deposit date: | 2014-06-03 | | Release date: | 2014-07-16 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
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3J7Y | | STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HUMAN MITOCHONDRIA | | Descriptor: | 16S rRNA, mt-tRNAVal, uL2, ... | | Authors: | Brown, A., Amunts, A., Bai, X.C., Sugimoto, Y., Edwards, P.C., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V. | | Deposit date: | 2014-08-26 | | Release date: | 2014-10-15 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structure of the large ribosomal subunit from human mitochondria.
Science, 346, 2014
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4V8Y | | CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX | | Descriptor: | 40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ... | | Authors: | Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W. | | Deposit date: | 2013-07-20 | | Release date: | 2014-07-09 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
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4V8Z | | CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX | | Descriptor: | 40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ... | | Authors: | Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W. | | Deposit date: | 2013-07-20 | | Release date: | 2014-07-09 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
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5G5P | | STRUCTURE OF THE SACCHAROMYCES CEREVISIAE TREX-2 COMPLEX | | Descriptor: | NUCLEAR MRNA EXPORT PROTEIN SAC3, NUCLEAR MRNA EXPORT PROTEIN THP1, 26S PROTEASOME COMPLEX SUBUNIT SEM1 | | Authors: | Aibara, S., Bai, X.C., Stewart, M. | | Deposit date: | 2016-05-26 | | Release date: | 2016-11-23 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (5.3 Å) | | Cite: | The Sac3 Tpr-Like Region in the Saccharomyces Cerevisiae Trex-2 Complex is More Extensive But Independent of the Cid Region
J.Struct.Biol., 195, 2016
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5GAP | | BODY REGION OF THE U4/U6.U5 TRI-SNRNP | | Descriptor: | U4 snRNA, 5' region, nucleotides 1-67, ... | | Authors: | Nguyen, T.H.D., Galej, W.P., Oubridge, C., Bai, X.C., Newman, A., Scheres, S., Nagai, K. | | Deposit date: | 2015-12-15 | | Release date: | 2016-01-27 | | Last modified: | 2019-10-02 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
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5MZ6 | | CRYO-EM STRUCTURE OF A SEPARASE-SECURIN COMPLEX FROM CAENORHABDITIS ELEGANS AT 3.8 A RESOLUTION | | Descriptor: | SEParase, Interactor of FizzY protein | | Authors: | Boland, A., Martin, T.G., Zhang, Z., Yang, J., Bai, X.C., Chang, L., Scheres, S.H.W., Barford, D. | | Deposit date: | 2017-01-31 | | Release date: | 2017-03-08 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.
Nat. Struct. Mol. Biol., 24, 2017
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5OOL | | STRUCTURE OF A NATIVE ASSEMBLY INTERMEDIATE OF THE HUMAN MITOCHONDRIAL RIBOSOME WITH UNFOLDED INTERFACIAL RRNA | | Descriptor: | 16S ribosomal RNA, mitochondrial tRNAVal, 39S ribosomal protein L2, ... | | Authors: | Brown, A., Rathore, S., Kimanius, D., Aibara, S., Bai, X.C., Rorbach, J., Amunts, A., Ramakrishnan, V. | | Deposit date: | 2017-08-08 | | Release date: | 2017-09-13 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
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5OOM | | STRUCTURE OF A NATIVE ASSEMBLY INTERMEDIATE OF THE HUMAN MITOCHONDRIAL RIBOSOME WITH UNFOLDED INTERFACIAL RRNA | | Descriptor: | 16S ribosomal RNA, mitochondrial tRNAVal, 39S ribosomal protein L2, ... | | Authors: | Brown, A., Rathore, S., Kimanius, D., Aibara, S., Bai, X.C., Rorbach, J., Amunts, A., Ramakrishnan, V. | | Deposit date: | 2017-08-08 | | Release date: | 2017-09-13 | | Last modified: | 2019-12-11 | | Method: | ELECTRON MICROSCOPY (3.03 Å) | | Cite: | Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
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6D7W | | CRYO-EM STRUCTURE OF THE MITOCHONDRIAL CALCIUM UNIPORTER FROM N. FISCHERI AT 3.8 ANGSTROM RESOLUTION | | Descriptor: | Mitochondrial calcium uniporter, CALCIUM ION | | Authors: | Nguyen, N.X., Armache, J.P., Cheng, Y., Bai, X.C. | | Deposit date: | 2018-04-25 | | Release date: | 2018-07-11 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM structure of a fungal mitochondrial calcium uniporter.
Nature, 559, 2018
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6D80 | | CRYO-EM STRUCTURE OF THE MITOCHONDRIAL CALCIUM UNIPORTER FROM N. FISCHERI BOUND TO SAPOSIN | | Descriptor: | Saposin A, Mitochondrial calcium uniporter, CALCIUM ION | | Authors: | Nguyen, N.X., Armache, J.P., Cheng, Y., Bai, X.C. | | Deposit date: | 2018-04-25 | | Release date: | 2018-07-11 | | Last modified: | 2019-11-20 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Cryo-EM structure of a fungal mitochondrial calcium uniporter.
Nature, 559, 2018
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6PXV | | CRYO-EM STRUCTURE OF FULL-LENGTH INSULIN RECEPTOR BOUND TO 4 INSULIN. 3D REFINEMENT WAS FOCUSED ON THE EXTRACELLULAR REGION. | | Descriptor: | Insulin receptor, Insulin | | Authors: | Uchikawa, E., Choi, E., Shang, G.J., Yu, H.T., Bai, X.C. | | Deposit date: | 2019-07-27 | | Release date: | 2019-09-04 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Activation mechanism of the insulin receptor revealed by cryo-EM structure of the fully liganded receptor-ligand complex.
Elife, 8, 2019
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