Author results

4WF1
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CRYSTAL STRUCTURE OF THE E. COLI RIBOSOME BOUND TO NEGAMYCIN.
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Olivier, N.B., Altman, R.B., Noeske, J., Basarab, G.S., Code, E., Ferguson, A.D., Gao, N., Huang, J., Juette, M.F., Livchak, S., Miller, M.D., Prince, D.B., Cate, J.H.D., Buurman, E.T., Blanchard, S.C.
Deposit date:2014-09-11
Release date:2014-11-05
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4YBB
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HIGH-RESOLUTION STRUCTURE OF THE ESCHERICHIA COLI RIBOSOME
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Noeske, J., Wasserman, M.R., Terry, D.S., Altman, R.B., Blanchard, S.C., Cate, J.H.D.
Deposit date:2015-02-18
Release date:2015-03-18
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High-resolution structure of the Escherichia coli ribosome.
Nat.Struct.Mol.Biol., 22, 2015
4Z3S
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ANTIBIOTIC A201A, MRNA AND THREE TRNAS IN THE A, P AND E SITES AT 2.65A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Polikanov, Y.S., Starosta, A.L., Juette, M.F., Altman, R.B., Terry, D.S., Lu, W., Burnett, B.J., Dinos, G., Reynolds, K., Blanchard, S.C., Steitz, T.A., Wilson, D.N.
Deposit date:2015-03-31
Release date:2015-06-03
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
5DOX
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH HYGROMYCIN-A AT 3.1A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Polikanov, Y.S., Starosta, A.L., Juette, M.F., Altman, R.B., Terry, D.S., Lu, W., Burnett, B.J., Dinos, G., Reynolds, K., Blanchard, S.C., Steitz, T.A., Wilson, D.N.
Deposit date:2015-09-11
Release date:2015-12-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
5DOY
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH ANTIBIOTIC HYGROMYCIN A, MRNA AND THREE TRNAS IN THE A, P AND E SITES AT 2.6A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S Ribosomal Protein L2, ...
Authors:Polikanov, Y.S., Starosta, A.L., Juette, M.F., Altman, R.B., Terry, D.S., Lu, W., Burnett, B.J., Dinos, G., Reynolds, K., Blanchard, S.C., Steitz, T.A., Wilson, D.N.
Deposit date:2015-09-11
Release date:2015-12-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
3J0L
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 9.8A CRYO-EM MAP: CLASSIC PRE STATE 1
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S5, Ribosomal protein S14, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-04
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3J0O
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 9A CRYO-EM MAP: CLASSIC PRE STATE 2
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S5, Ribosomal protein S14, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-05
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3J0P
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 10.6A CRYO-EM MAP: ROTATED PRE STATE 1
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S15, Ribosomal protein S23, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-06
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10.6 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3J0Q
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 10.6A CRYO-EM MAP: ROTATED PRE STATE 2
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S15, Ribosomal protein S23, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-11
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10.6 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
4V9C
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ALLOSTERIC CONTROL OF THE RIBOSOME BY SMALL-MOLECULE ANTIBIOTICS
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Cate, J.H.D., Pulk, A., Blanchard, S.C., Wang, L., Feldman, M.B., Wasserman, M.R., Altman, R.
Deposit date:2012-07-25
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Allosteric control of the ribosome by small-molecule antibiotics.
Nat.Struct.Mol.Biol., 19, 2012
4WOI
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4,5-LINKED AMINOGLYCOSIDE ANTIBIOTICS REGULATE THE BACTERIAL RIBOSOME BY TARGETING DYNAMIC CONFORMATIONAL PROCESSES WITHIN INTERSUBUNIT BRIDGE B2
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Pulk, A., Cate, J.H.D., Blanchard, S., Wasserman, M., Altman, R., Zhou, Z., Zinder, J., Green, K., Garneau-Tsodikova, S.
Deposit date:2014-10-15
Release date:2015-08-05
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.
Nat Commun, 6, 2015
4X2S
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CRYSTAL STRUCTURE OF 276S/M395R-GLTPH IN INWARD-FACING CONFORMATION
Descriptor:425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, SODIUM ION
Authors:Akyuz, N., Boudker, O.
Deposit date:2014-11-26
Release date:2015-02-04
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (4.21 Å)
Cite:Transport domain unlocking sets the uptake rate of an aspartate transporter.
Nature, 518, 2015
5IT8
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HIGH-RESOLUTION STRUCTURE OF THE ESCHERICHIA COLI RIBOSOME
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Cocozaki, A., Ferguson, A.
Deposit date:2016-03-16
Release date:2016-07-27
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J5B
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STRUCTURE OF THE WT E COLI RIBOSOME BOUND TO TETRACYCLINE
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Cocozaki, A., Ferguson, A.
Deposit date:2016-04-01
Release date:2016-07-27
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J7L
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STRUCTURE OF THE 70S E COLI RIBOSOME WITH THE U1052G MUTATION IN THE 16S RRNA BOUND TO TETRACYCLINE
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Cocozaki, A., Ferguson, A.
Deposit date:2016-04-06
Release date:2016-07-27
Last modified:2018-08-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J88
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STRUCTURE OF THE E COLI 70S RIBOSOME WITH THE U1060A MUTATION IN 16S RRNA
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Cocozaki, A., Ferguson, A.
Deposit date:2016-04-07
Release date:2016-07-06
Last modified:2016-12-07
Method:X-RAY DIFFRACTION (3.32 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J8A
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STRUCTURE OF THE E COLI 70S RIBOSOME WITH THE U1052G MUTATION IN 16S RRNA BOUND TO TIGECYCLINE
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Cocozaki, A., Ferguson, A.
Deposit date:2016-04-07
Release date:2016-07-06
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5J91
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STRUCTURE OF THE WILD-TYPE 70S E COLI RIBOSOME BOUND TO TIGECYCLINE
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Cocozaki, A., Ferguson, A.
Deposit date:2016-04-08
Release date:2016-07-06
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JC9
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STRUCTURE OF THE ESCHERICHIA COLI RIBOSOME WITH THE U1052G MUTATION IN THE 16S RRNA
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Cocozaki, A., Ferguson, A.
Deposit date:2016-04-14
Release date:2016-07-06
Last modified:2016-08-03
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors.
Proc.Natl.Acad.Sci.USA, 113, 2016
5NDG
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CRYSTAL STRUCTURE OF GENETICIN (G418) BOUND TO THE YEAST 80S RIBOSOME
Descriptor:18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-08
Release date:2017-12-13
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDJ
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE TC007 IN COMPLEX WITH 70S RIBOSOME FROM THERMUS THERMOPHILUS, THREE TRNAS AND MRNA (SOAKING)
Descriptor:16S ribosomal RNA, 50S ribosomal protein L18, 50S ribosomal protein L23, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-08
Release date:2018-05-02
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDK
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE TC007 CO-CRYSTALLIZED WITH 70S RIBOSOME FROM THERMUS THERMOPHILUS, THREE TRNAS AND MRNA
Descriptor:16S ribosomal RNA, 50S ribosomal protein L18, 50S ribosomal protein L23, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-08
Release date:2017-12-13
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDV
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CRYSTAL STRUCTURE OF PAROMOMYCIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-09
Release date:2017-12-13
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NDW
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE TC007 BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 18S ribosomal RNA, 5S ribosomal RNA, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-03-09
Release date:2017-12-13
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5OBM
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CRYSTAL STRUCTURE OF GENTAMICIN BOUND TO THE YEAST 80S RIBOSOME
Descriptor:25S ribosomal RNA, 5S Ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Prokhorova, I., Djumagulov, M., Urzhumtsev, A., Yusupov, M., Yusupova, G.
Deposit date:2017-06-28
Release date:2017-12-13
Last modified:2017-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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