Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
3LD8
DownloadVisualize
BU of 3ld8 by Molmil
Structure of JMJD6 and Fab Fragments
Descriptor: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, FE (III) ION, GLYCEROL, ...
Authors:Hong, X, Zang, J, White, J, Kappler, J.W, Wang, C, Zhang, G.
Deposit date:2010-01-12
Release date:2010-08-04
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interaction of JMJD6 with single-stranded RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
3LDB
DownloadVisualize
BU of 3ldb by Molmil
Structure of JMJD6 complexd with ALPHA-KETOGLUTARATE and Fab Fragment.
Descriptor: 2-OXOGLUTARIC ACID, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, FE (III) ION, ...
Authors:Hong, X, Zang, J, White, J, Kappler, J.W, Wang, C, Zhang, G.
Deposit date:2010-01-12
Release date:2010-08-04
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Interaction of JMJD6 with single-stranded RNA.
Proc.Natl.Acad.Sci.USA, 107, 2010
449D
DownloadVisualize
BU of 449d by Molmil
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BENZIMIDAZOLE DERIVATIVE COMPLEX
Descriptor: 2'-(3-IODOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Squire, C.J, Baker, L.J, Clark, G.R, Martin, R.F, White, J.
Deposit date:1999-01-20
Release date:2000-02-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
445D
DownloadVisualize
BU of 445d by Molmil
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', Benzimidazole derivative complex
Descriptor: 2'-(3-IODOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Squire, C.J, Baker, L.J, Clark, G.R, Martin, R.F, White, J.
Deposit date:1999-01-14
Release date:2000-02-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
448D
DownloadVisualize
BU of 448d by Molmil
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BENZIMIDAZOLE DERIVATIVE COMPLEX
Descriptor: 2'-(3-IODO-4-METHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Clark, G.R, Squire, C.J, Martin, R.F, White, J.
Deposit date:1999-01-20
Release date:2000-02-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
443D
DownloadVisualize
BU of 443d by Molmil
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'/ BENZIMIDAZOLE DERIVATIVE COMPLEX
Descriptor: 2'-(3-IODOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Squire, C.J, Baker, L.J, Clark, G.R, Martin, R.F, White, J.
Deposit date:1999-01-14
Release date:2000-02-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
447D
DownloadVisualize
BU of 447d by Molmil
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'
Descriptor: 2'-(4-DIMETHYLAMINOPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Squire, C.J, Baker, L.J, Clark, G.R, Martin, R.F, White, J.
Deposit date:1999-01-18
Release date:2000-03-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
442D
DownloadVisualize
BU of 442d by Molmil
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BENZIMIDAZOLE DERIVATIVE COMPLEX
Descriptor: 2'-(3-IODO-4-METHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
Authors:Clark, G.R, Squire, C.J, Martin, R.F, White, J.
Deposit date:1999-01-14
Release date:2000-02-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
444D
DownloadVisualize
BU of 444d by Molmil
5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', BENZIMIDAZOLE DERIVATIVE COMPLEX
Descriptor: 2'-(3-IODO-4-METHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3')
Authors:Clark, G.R, Squire, C.J, Martin, R.F, White, J.
Deposit date:1999-01-14
Release date:2000-02-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of m-iodo Hoechst-DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design.
Nucleic Acids Res., 28, 2000
1OJY
DownloadVisualize
BU of 1ojy by Molmil
Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK2
DownloadVisualize
BU of 1ok2 by Molmil
Decay accelerating factor (CD55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OJV
DownloadVisualize
BU of 1ojv by Molmil
Decay accelerating factor (CD55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK1
DownloadVisualize
BU of 1ok1 by Molmil
Decay accelerating factor (cd55) : the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK3
DownloadVisualize
BU of 1ok3 by Molmil
Decay accelerating factor (cd55): the structure of an intact human complement regulator.
Descriptor: ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OK9
DownloadVisualize
BU of 1ok9 by Molmil
Decay accelerating factor (CD55): The structure of an intact human complement regulator.
Descriptor: ACETATE ION, CHLORIDE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, ...
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-21
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
1OJW
DownloadVisualize
BU of 1ojw by Molmil
Decay accelerating factor (CD55): the structure of an intact human complement regulator.
Descriptor: COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, SULFATE ION
Authors:Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M.
Deposit date:2003-07-16
Release date:2004-01-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor
Proc.Natl.Acad.Sci.USA, 101, 2004
6PD2
DownloadVisualize
BU of 6pd2 by Molmil
PntC-AEPT: fusion protein of phosphonate-specific cytidylyltransferase and 2-aminoethylphosphonate (AEP) transaminase from Treponema denticola in complex with cytidine monophosphate-AEP
Descriptor: 1,2-ETHANEDIOL, 5'-O-[(S)-{[(R)-(2-aminoethyl)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, ACETATE ION, ...
Authors:Suits, M.D.L, Whiteside, J.
Deposit date:2019-06-18
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis.
Nat Commun, 10, 2019
6PD1
DownloadVisualize
BU of 6pd1 by Molmil
PntC-AEPT: fusion protein of phosphonate-specific cytidylyltransferase and 2-aminoethylphosphonate (AEP) transaminase from Treponema denticola
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ...
Authors:Suits, M.D.L, Whiteside, J.
Deposit date:2019-06-18
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis.
Nat Commun, 10, 2019
1KA6
DownloadVisualize
BU of 1ka6 by Molmil
SAP/SH2D1A bound to peptide n-pY
Descriptor: SH2 DOMAIN PROTEIN 1A, peptide n-pY
Authors:Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C.
Deposit date:2001-10-31
Release date:2001-11-07
Last modified:2021-10-27
Method:SOLUTION NMR
Cite:A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
EMBO J., 21, 2002
1KA7
DownloadVisualize
BU of 1ka7 by Molmil
SAP/SH2D1A bound to peptide n-Y-c
Descriptor: SH2 DOMAIN PROTEIN 1A, peptide n-Y-c
Authors:Hwang, P.M, Li, C, Morra, M, Lillywhite, J, Gertler, F, Terhorst, C, Kay, L.E, Pawson, T, Forman-Kay, J, Li, S.-C.
Deposit date:2001-10-31
Release date:2001-11-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A "three-pronged" binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome.
EMBO J., 21, 2002
1TN0
DownloadVisualize
BU of 1tn0 by Molmil
Structure of bacterorhodopsin mutant A51P
Descriptor: Bacteriorhodopsin, RETINAL
Authors:Yohannan, S, Yang, D, Faham, S, Boulting, G, Whitelegge, J, Bowie, J.U.
Deposit date:2004-06-11
Release date:2004-10-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Proline substitutions are not easily accommodated in a membrane protein
J.Mol.Biol., 341, 2004
1TN5
DownloadVisualize
BU of 1tn5 by Molmil
Structure of bacterorhodopsin mutant K41P
Descriptor: Bacteriorhodopsin, RETINAL
Authors:Yohannan, S, Yang, D, Faham, S, Boulting, G, Whitelegge, J, Bowie, J.U.
Deposit date:2004-06-11
Release date:2004-10-19
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Proline substitutions are not easily accommodated in a membrane protein
J.Mol.Biol., 341, 2004
6E0B
DownloadVisualize
BU of 6e0b by Molmil
Plasmodium falciparum dihydroorotate dehydrogenase C276F mutant bound with triazolopyrimidine-based inhibitor DSM1
Descriptor: 5-methyl-7-(naphthalen-2-ylamino)-1H-[1,2,4]triazolo[1,5-a]pyrimidine-3,8-diium, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Tomchick, D.R, Phillips, M.A, Deng, X.
Deposit date:2018-07-06
Release date:2018-11-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Identification and Mechanistic Understanding of Dihydroorotate Dehydrogenase Point Mutations in Plasmodium falciparum that Confer in Vitro Resistance to the Clinical Candidate DSM265.
ACS Infect Dis, 5, 2019
5FI8
DownloadVisualize
BU of 5fi8 by Molmil
Crystal structure of plasmodium falciparum dihydroorotate dehydrogenase bounded with DSM422 (Tetrahydro-2-naphthyl and 2-indanyl triazolopyrimidine)
Descriptor: 2-[1,1-bis(fluoranyl)ethyl]-~{N}-[(2~{S})-7-bromanyl-1,2,3,4-tetrahydronaphthalen-2-yl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine, Dihydroorotate dehydrogenase (quinone), mitochondrial, ...
Authors:Deng, X, Kokkonda, S, Tomchick, D, Phillips, M.
Deposit date:2015-12-22
Release date:2016-05-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity.
J.Med.Chem., 59, 2016
6VTN
DownloadVisualize
BU of 6vtn by Molmil
Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with Inhibitor DSM557
Descriptor: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ...
Authors:Deng, X, Phillips, M.
Deposit date:2020-02-13
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.
J.Med.Chem., 63, 2020

 

1234>

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon