6PD2

PntC-AEPT: fusion protein of phosphonate-specific cytidylyltransferase and 2-aminoethylphosphonate (AEP) transaminase from Treponema denticola in complex with cytidine monophosphate-AEP

Summary for 6PD2

Entry DOI	10.2210/pdb6pd2/pdb
Descriptor	Nucleotidyl transferase/aminotransferase, class V, PYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, ... (9 entities in total)
Functional Keywords	phosphonate, cytidylyltransferase, cytidine monophosphate- 2-aminoethylphosphonate (cmp-aep), biosynthetic protein
Biological source	Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222)
Total number of polymer chains	4
Total formula weight	286580.54
Authors	Suits, M.D.L.,Whiteside, J. (deposition date: 2019-06-18, release date: 2019-08-07, Last modification date: 2023-10-11)
Primary citation	Rice, K.,Batul, K.,Whiteside, J.,Kelso, J.,Papinski, M.,Schmidt, E.,Pratasouskaya, A.,Wang, D.,Sullivan, R.,Bartlett, C.,Weadge, J.T.,Van der Kamp, M.W.,Moreno-Hagelsieb, G.,Suits, M.D.,Horsman, G.P. The predominance of nucleotidyl activation in bacterial phosphonate biosynthesis. Nat Commun, 10:3698-3698, 2019 Cited by PubMed: 31420548 DOI: 10.1038/s41467-019-11627-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation