Author results

4V4B
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STRUCTURE OF THE RIBOSOMAL 80S-EEF2-SORDARIN COMPLEX FROM YEAST OBTAINED BY DOCKING ATOMIC MODELS FOR RNA AND PROTEIN COMPONENTS INTO A 11.7 A CRYO-EM MAP.
Descriptor:18S ribosomal RNA, Elongation factor 2, 40S ribosomal protein S0-A, ...
Authors:Spahn, C.M., Gomez-Lorenzo, M.G., Grassucci, R.A., Jorgensen, R., Andersen, G.R., Beckmann, R., Penczek, P.A., Ballesta, J.P.G., Frank, J.
Deposit date:2004-01-06
Release date:2014-07-09
Last modified:2015-03-18
Method:ELECTRON MICROSCOPY (11.7 Å)
Cite:Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
1RY1
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STRUCTURE OF THE SIGNAL RECOGNITION PARTICLE INTERACTING WITH THE ELONGATION-ARRESTED RIBOSOME
Descriptor:SRP Alu domain, SRP S domain, SRP RNA, ...
Authors:Halic, M., Becker, T., Pool, M.R., Spahn, C.M., Grassucci, R.A., Frank, J., Beckmann, R.
Deposit date:2003-12-19
Release date:2004-04-20
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Structure of the signal recognition particle interacting with the elongation-arrested ribosome
Nature, 427, 2004
1T1M
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BINDING POSITION OF RIBOSOME RECYCLING FACTOR (RRF) ON THE E. COLI 70S RIBOSOME
Descriptor:dodecamer fragment of double helix from 23S rRNA, 42-mer fragment of double helix from 16S rRNA, ribosome recycling factor
Authors:Agrawal, R.K., Sharma, M.R., Kiel, M.C., Hirokawa, G., Booth, T.M., Spahn, C.M., Grassucci, R.A., Kaji, A., Frank, J.
Deposit date:2004-04-16
Release date:2004-06-15
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications
Proc.Natl.Acad.Sci.USA, 101, 2004
1T1O
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COMPONENTS OF THE CONTROL 70S RIBOSOME TO PROVIDE REFERENCE FOR THE RRF BINDING SITE
Descriptor:dodecamer fragment of double helix from 23S rRNA, 19-mer fragment of the 23S rRNA, 42-mer fragment of double helix from 16S rRNA
Authors:Agrawal, R.K., Sharma, M.R., Kiel, M.C., Hirokawa, G., Booth, T.M., Spahn, C.M., Grassucci, R.A., Kaji, A., Frank, J.
Deposit date:2004-04-16
Release date:2004-06-15
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: Functional implications
Proc.Natl.Acad.Sci.USA, 101, 2004
1TRJ
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HOMOLOGY MODEL OF YEAST RACK1 PROTEIN FITTED INTO 11.7A CRYO-EM MAP OF YEAST 80S RIBOSOME
Descriptor:Helix 39 of 18S rRNA, Helix 40 of 18S rRNA, Guanine nucleotide-binding protein beta subunit-like protein
Authors:Sengupta, J., Nilsson, J., Gursky, R., Spahn, C.M., Nissen, P., Frank, J.
Deposit date:2004-06-21
Release date:2004-09-28
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (11.7 Å)
Cite:Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM
Nat.Struct.Mol.Biol., 11, 2004
1YSH
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LOCALIZATION AND DYNAMIC BEHAVIOR OF RIBOSOMAL PROTEIN L30E
Descriptor:RNA (28-MER), RNA (34-MER), RNA (101-MER), ...
Authors:Halic, M., Becker, T., Frank, J., Spahn, C.M., Beckmann, R.
Deposit date:2005-02-08
Release date:2005-07-05
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:Localization and dynamic behavior of ribosomal protein L30e
Nat.Struct.Mol.Biol., 12, 2005
3J0L
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 9.8A CRYO-EM MAP: CLASSIC PRE STATE 1
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S5, Ribosomal protein S14, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-04
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3J0O
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 9A CRYO-EM MAP: CLASSIC PRE STATE 2
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S5, Ribosomal protein S14, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-05
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3J0P
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 10.6A CRYO-EM MAP: ROTATED PRE STATE 1
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S15, Ribosomal protein S23, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-06
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10.6 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
3J0Q
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CORE OF MAMMALIAN 80S PRE-RIBOSOME IN COMPLEX WITH TRNAS FITTED TO A 10.6A CRYO-EM MAP: ROTATED PRE STATE 2
Descriptor:40S ribosomal RNA fragment, Ribosomal protein S15, Ribosomal protein S23, ...
Authors:Budkevich, T., Giesebrecht, J., Altman, R., Munro, J., Mielke, T., Nierhaus, K., Blanchard, S., Spahn, C.M.
Deposit date:2011-10-11
Release date:2011-11-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (10.6 Å)
Cite:Structure and dynamics of the Mammalian ribosomal pretranslocation complex.
Mol.Cell, 44, 2011
1EG0
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FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME
Descriptor:FRAGMENT OF 16S RRNA HELIX 23, FRAGMENT OF 23S RRNA, HELIX 95 OF 23S RRNA, ...
Authors:Gabashvili, I.S., Agrawal, R.K., Spahn, C.M.T., Grassucci, R.A., Svergun, D.I., Frank, J., Penczek, P.
Deposit date:2000-02-11
Release date:2000-03-06
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Solution structure of the E. coli 70S ribosome at 11.5 A resolution.
Cell(Cambridge,Mass.), 100, 2000
1FCW
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TRNA POSITIONS DURING THE ELONGATION CYCLE
Descriptor:TRNAPHE
Authors:Agrawal, R.K., Spahn, C.M.T., Penczek, P., Grassucci, R.A., Nierhaus, K.H., Frank, J.
Deposit date:2000-07-19
Release date:2000-08-11
Last modified:2011-07-13
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle.
J.Cell Biol., 150, 2000
2NOQ
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STRUCTURE OF RIBOSOME-BOUND CRICKET PARALYSIS VIRUS IRES RNA
Descriptor:CrPV IRES, 18S ribosomal RNA, 25S ribosomal RNA, ...
Authors:Schuler, M., Connell, S.R., Lescoute, A., Giesebrecht, J., Dabrowski, M., Schroeer, B., Mielke, T., Penczek, P.A., Westhof, E., Spahn, C.M.T.
Deposit date:2006-10-26
Release date:2006-11-21
Last modified:2012-02-15
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structure of the ribosome-bound cricket paralysis virus IRES RNA.
Nat.Struct.Mol.Biol., 13, 2006
2OM7
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STRUCTURAL BASIS FOR INTERACTION OF THE RIBOSOME WITH THE SWITCH REGIONS OF GTP-BOUND ELONGATION FACTORS
Descriptor:Fragment of 16S rRNA (h14), Fragment of 16S rRNA (h15), Fragment of 16S rRNA (h44), ...
Authors:Connell, S.R., Wilson, D.N., Rost, M., Schueler, M., Giesebrecht, J., Dabrowski, M., Mielke, T., Fucini, P., Spahn, C.M.T.
Deposit date:2007-01-21
Release date:2008-01-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.
Mol.Cell, 25, 2007
2ZJP
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THIOPEPTIDE ANTIBIOTIC NOSIHEPTIDE BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS
Descriptor:50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-07
Release date:2008-06-17
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
2ZJQ
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INTERACTION OF L7 WITH L11 INDUCED BY MICROCCOCIN BINDING TO THE DEINOCOCCUS RADIODURANS 50S SUBUNIT
Descriptor:ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-08
Release date:2008-06-17
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
2ZJR
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REFINED NATIVE STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) FROM DEINOCOCCUS RADIODURANS
Descriptor:ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-08
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
3CF5
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THIOPEPTIDE ANTIBIOTIC THIOSTREPTON BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS
Descriptor:50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ...
Authors:Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
Deposit date:2008-03-02
Release date:2008-06-17
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
3JCJ
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STRUCTURES OF RIBOSOME-BOUND INITIATION FACTOR 2 REVEAL THE MECHANISM OF SUBUNIT ASSOCIATION
Descriptor:5S ribosomal RNA, 30S ribosomal protein S18, 30S ribosomal protein S21, ...
Authors:Sprink, T., Ramrath, D.J.F., Yamamoto, H., Yamamoto, K., Loerke, J., Ismer, J., Hildebrand, P.W., Scheerer, P., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2015-12-18
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
3JCN
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STRUCTURES OF RIBOSOME-BOUND INITIATION FACTOR 2 REVEAL THE MECHANISM OF SUBUNIT ASSOCIATION: INITIATION COMPLEX I
Descriptor:50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, ...
Authors:Sprink, T., Ramrath, D.J.F., Yamamoto, H., Yamamoto, K., Loerke, J., Ismer, J., Hildebrand, P.W., Scheerer, P., Buerger, J., Mielke, T., Spahn, C.M.T.
Deposit date:2016-01-04
Release date:2016-03-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
3RGW
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CRYSTAL STRUCTURE AT 1.5 A RESOLUTION OF AN H2-REDUCED, O2-TOLERANT HYDROGENASE FROM RALSTONIA EUTROPHA UNMASKS A NOVEL IRON-SULFUR CLUSTER
Descriptor:Membrane-bound hydrogenase (NIFE) large subunit HOXG, Membrane-bound hydrogenase (NIFE) small subunit HOXK, formyl[bis(hydrocyanato-1kappaC)]ironnickel(Fe-Ni), ...
Authors:Scheerer, P., Fritsch, J., Frielingsdorf, S., Kroschinsky, S., Friedrich, B., Lenz, O., Spahn, C.M.T.
Deposit date:2011-04-10
Release date:2011-10-26
Last modified:2011-11-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre.
Nature, 479, 2011
4CXG
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:18S RRNA - H44, 28S RRNA - H89, ELONGATION FACTOR 1A, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-07
Release date:2014-07-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.7 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4CXH
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:18S RRNA - H44, 28S RRNA - H89, ELONGATION FACTOR 1A, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-07
Release date:2014-07-16
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4UJE
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REGULATION OF THE MAMMALIAN ELONGATION CYCLE BY 40S SUBUNIT ROLLING: A EUKARYOTIC-SPECIFIC RIBOSOME REARRANGEMENT
Descriptor:TRNA-LYS, TRNA-PHE, Messenger RNA, ...
Authors:Budkevich, T.V., Giesebrecht, J., Behrmann, E., Loerke, J., Ramrath, D.J.F., Mielke, T., Ismer, J., Hildebrand, P., Tung, C.-S., Nierhaus, K.H., Sanbonmatsu, K.Y., Spahn, C.M.T.
Deposit date:2014-04-05
Release date:2014-07-16
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Regulation of the Mammalian Elongation Cycle by Subunit Rolling: A Eukaryotic-Specific Ribosome Rearrangement.
Cell(Cambridge,Mass.), 158, 2014
4V68
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T. THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH MRNA, TRNAS AND EF-TU.GDP.KIRROMYCIN TERNARY COMPLEX, FITTED TO A 6.4 A CRYO-EM MAP.
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S4, ...
Authors:Schuette, J.-C., Spahn, C.M.T.
Deposit date:2008-12-11
Release date:2014-07-09
Last modified:2015-03-25
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:GTPase activation of elongation factor EF-Tu by the ribosome during decoding
Embo J., 28, 2009
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