T. thermophilus 70S ribosome in complex with mRNA, tRNAs and EF-Tu.GDP.kirromycin ternary complex, fitted to a 6.4 A Cryo-EM map.

This is a large structure.

Summary for 4V68

Integrates3FIC 3FIN
EMDB information5030
Descriptor16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S4, ... (64 entities in total)
Functional Keywordscryo-electron microscopy/elongation factor/gtpase/ribosome/translation, ribonucleoprotein, ribosomal protein, rna-binding, rrna-binding, metal-binding, zinc-finger, trna-binding, elongation factor, gtp-binding, nucleotide-binding, phosphoprotein, protein biosynthesis, ribosome
Biological sourceThermus thermophilus
Cellular locationCytoplasm Q5SHN6 P60339
Total number of polymer chains60
Total molecular weight2263662.84
Schuette, J.-C.,Spahn, C.M.T. (deposition date: 2008-12-11, release date: 2014-07-09, Last modification date: 2015-03-25)
Primary citation
Schuette, J.C.,Murphy, F.V.,Kelley, A.C.,Weir, J.R.,Giesebrecht, J.,Connell, S.R.,Loerke, J.,Mielke, T.,Zhang, W.,Penczek, P.A.,Ramakrishnan, V.,Spahn, C.M.
GTPase activation of elongation factor EF-Tu by the ribosome during decoding
Embo J., 28:755-765, 2009
PubMed: 19229291 (PDB entries with the same primary citation)
DOI: 10.1038/emboj.2009.26
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone4813.8%10.3%0.53MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 4v68
no rotation
Molmil generated image of 4v68
rotated about x axis by 90°
Molmil generated image of 4v68
rotated about y axis by 90°