Author results

1AM4
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COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS)
分子名称:P50-RHOGAP, CDC42HS, MAGNESIUM ION, ...
著者Rittinger, K., Walker, P., Gamblin, S.J., Smerdon, S.J.
登録日1997-06-22
公開日1998-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP.
Nature, 388, 1997
1QJA
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14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2)
分子名称:14-3-3 PROTEIN ZETA, PHOSPHOPEPTIDE
著者Rittinger, K., Budman, J., Xu, J., Volinia, S., Cantley, L.C., Smerdon, S.J., Gamblin, S.J., Yaffe, M.B.
登録日1999-06-23
公開日1999-09-15
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding
Mol.Cell, 4, 1999
1QJB
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14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 1)
分子名称:14-3-3 PROTEIN ZETA/DELTA, PHOSPHOPEPTIDE
著者Rittinger, K., Budman, J., Xu, J., Volinia, S., Cantley, L.C., Smerdon, S.J., Gamblin, S.J., Yaffe, M.B.
登録日1999-06-23
公開日1999-09-15
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding
Mol.Cell, 4, 1999
1TX4
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RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX
分子名称:P50-RHOGAP, TRANSFORMING PROTEIN RHOA, MAGNESIUM ION, ...
著者Rittinger, K., Walker, P.A., Smerdon, S.J., Gamblin, S.J.
登録日1997-07-29
公開日1998-09-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue.
Nature, 389, 1997
5FER
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COMPLEX OF TRIM25 RING WITH UBCH5-UB
分子名称:E3 ubiquitin/ISG15 ligase TRIM25, Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-40S ribosomal protein S27a, ...
著者Rittinger, K., Koliopoulos, M.G., Esposito, D.
登録日2015-12-17
公開日2016-05-18
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Embo J., 35, 2016
5FEY
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TRIM32 RING
分子名称:E3 ubiquitin-protein ligase TRIM32, ZINC ION
著者Rittinger, K., Esposito, D., Koliopoulos, M.G.
登録日2015-12-17
公開日2016-05-18
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Embo J., 35, 2016
1E96
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STRUCTURE OF THE RAC/P67PHOX COMPLEX
分子名称:RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, RESIDUES 1-203, ...
著者Lapouge, K., Smith, S.J.M., Walker, P.A., Gamblin, S.J., Smerdon, S.J., Rittinger, K.
登録日2000-10-10
公開日2000-11-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the Tpr Domain of P67Phox in Complex with Rac.GTP
Mol.Cell, 6, 2000
1NG2
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STRUCTURE OF AUTOINHIBITED P47PHOX
分子名称:Neutrophil cytosolic factor 1
著者Groemping, Y., Lapouge, K., Smerdon, S.J., Rittinger, K.
登録日2002-12-16
公開日2003-05-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003
1OV3
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STRUCTURE OF THE P22PHOX-P47PHOX COMPLEX
分子名称:Neutrophil cytosol factor 1, Flavocytochrome b558 alpha polypeptide
著者Groemping, Y., Lapouge, K., Smerdon, S.J., Rittinger, K.
登録日2003-03-25
公開日2003-05-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003
6GZY
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HOIP-FRAGMENT5 COMPLEX
分子名称:E3 ubiquitin-protein ligase RNF31, methyl 4-[(2-oxidanylidene-1,5,6,7-tetrahydrocyclopenta[b]pyridin-3-yl)carbonylamino]butanoate, ZINC ION, ...
著者Johansson, H., Tsai, Y.C.I., Fantom, K., Chung, C.W., Martino, L., House, D., Rittinger, K.
登録日2018-07-05
公開日2019-01-30
最終更新日2019-02-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Fragment-Based Covalent Ligand Screening Enables Rapid Discovery of Inhibitors for the RBR E3 Ubiquitin Ligase HOIP.
J. Am. Chem. Soc., 141, 2019
5NT1
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COMPLEX OF INFLUENZA A NS1 EFFECTOR DOMAIN WITH TRIM25 COILED COIL
分子名称:E3 ubiquitin/ISG15 ligase TRIM25, Non-structural protein 1
著者Koliopoulos, M.G., Rittinger, K.
登録日2017-04-27
公開日2018-05-16
最終更新日2018-05-23
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
5NT2
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COMPLEX OF INFLUENZA A NS1 WITH TRIM25 COILED COIL DOMAIN
分子名称:Non-structural protein 1, E3 ubiquitin/ISG15 ligase TRIM25
著者Koliopoulos, M.G., Rittinger, K.
登録日2017-04-27
公開日2018-05-23
実験手法X-RAY DIFFRACTION (4.259 Å)
主引用文献Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
Nat Commun, 9, 2018
6EYR
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CRYSTAL STRUCTURE OF THE SALMONELLA EFFECTOR SSEK3
分子名称:Type III secretion system effector protein
著者Esposito, D., Rittinger, K.
登録日2017-11-13
公開日2018-02-28
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the glycosyltransferase activity of theSalmonellaeffector SseK3.
J. Biol. Chem., 293, 2018
6EYT
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CRYSTAL STRUCTURE OF THE SALMONELLA EFFECTOR SSEK3 IN COMPLEX WITH UDP-GLCNAC AND MANGANESE
分子名称:Type III secretion system effector protein, IODIDE ION, MANGANESE (II) ION, ...
著者Esposito, D., Rittinger, K.
登録日2017-11-13
公開日2018-02-28
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Structural basis for the glycosyltransferase activity of theSalmonellaeffector SseK3.
J. Biol. Chem., 293, 2018
1OW3
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CRYSTAL STRUCTURE OF RHOA.GDP.MGF3-IN COMPLEX WITH RHOGAP
分子名称:Rho-GTPase-activating protein 1, Transforming protein RhoA, MAGNESIUM ION, ...
著者Graham, D.L., Lowe, P.N., Grime, G.W., Marsh, M., Rittinger, K., Smerdon, S.J., Gamblin, S.J., Eccleston, J.F.
登録日2003-03-28
公開日2003-05-06
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer
Chem.Biol., 9, 2002
2AK5
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BETA PIX-SH3 COMPLEXED WITH A CBL-B PEPTIDE
分子名称:Rho guanine nucleotide exchange factor 7, 8-residue peptide from a signal transduction protein CBL-B
著者Jozic, D., Cardenes, N., Deribe, Y.L., Moncalian, G., Hoeller, D., Groemping, Y., Dikic, I., Rittinger, K., Bravo, J.
登録日2005-08-03
公開日2005-10-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Cbl promotes clustering of endocytic adaptor proteins.
Nat.Struct.Mol.Biol., 12, 2005
2VRW
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CRITICAL STRUCTURAL ROLE FOR THE PH AND C1 DOMAINS OF THE VAV1 EXCHANGE FACTOR
分子名称:RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, PROTO-ONCOGENE VAV, ZINC ION
著者Rapley, J., Tybulewicz, V., Rittinger, K.
登録日2008-04-16
公開日2008-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crucial Structural Role for the Ph and C1 Domains of the Vav1 Exchange Factor.
Embo Rep., 9, 2008
2W6A
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X-RAY STRUCTURE OF THE DIMERIC GIT1 COILED-COIL DOMAIN
分子名称:ARF GTPASE-ACTIVATING PROTEIN GIT1
著者Schlenker, O., Rittinger, K.
登録日2008-12-17
公開日2009-01-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structures of Dimeric Git1 and Trimeric Beta-Pix and Implications for Git-Pix Complex Assembly.
J.Mol.Biol., 386, 2009
2W6B
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CRYSTAL STRUCTURE OF THE TRIMERIC BETA-PIX COILED-COIL DOMAIN
分子名称:RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 7
著者Schlenker, O., Rittinger, K.
登録日2008-12-17
公開日2009-01-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Dimeric Git1 and Trimeric Beta-Pix and Implications for Git-Pix Complex Assembly.
J.Mol.Biol., 386, 2009
4EMO
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CRYSTAL STRUCTURE OF THE PH DOMAIN OF SHARPIN
分子名称:Sharpin
著者Stieglitz, B., Haire, L.F., Dikic, I., Rittinger, K.
登録日2012-04-12
公開日2012-05-02
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold.
J.Biol.Chem., 287, 2012
4LJO
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STRUCTURE OF AN ACTIVE LIGASE (HOIP)/UBIQUITIN TRANSFER COMPLEX
分子名称:E3 ubiquitin-protein ligase RNF31, Polyubiquitin-C, ZINC ION, ...
著者Rana, R.R., Stieglitz, B., Koliopoulos, M.G., Morris-Davies, A.C., Christodoulou, E., Howell, S., Brown, N.R., Rittinger, K.
登録日2013-07-05
公開日2013-10-16
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (1.564 Å)
主引用文献Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503, 2013
4LJP
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STRUCTURE OF AN ACTIVE LIGASE (HOIP-H889A)/UBIQUITIN TRANSFER COMPLEX
分子名称:E3 ubiquitin-protein ligase RNF31, Polyubiquitin-C, ZINC ION
著者Rana, R.R., Stieglitz, B., Koliopoulos, M.G., Morris-Davies, A.C., Christodoulou, E., Howell, S., Brown, N.R., Rittinger, K.
登録日2013-07-05
公開日2013-10-16
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503, 2013
4LJQ
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CRYSTAL STRUCTURE OF THE CATALYTIC CORE OF E3 LIGASE HOIP
分子名称:E3 ubiquitin-protein ligase RNF31, ZINC ION
著者Stieglitz, B., Rana, R.R., Koliopoulos, M.G., Morris-Davies, A.C., Christodoulou, E., Howell, S., Brown, N.R., Rittinger, K.
登録日2013-07-05
公開日2013-10-16
最終更新日2013-12-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503, 2013
6GGO
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CRYSTAL STRUCTURE OF SALMONELLA ZINC METALLOPROTEASE EFFECTOR GTGA
分子名称:Bacteriophage virulence determinant, ZINC ION, CHLORIDE ION
著者Jennings, E., Esposito, D., Rittinger, K., Thurston, T.
登録日2018-05-03
公開日2018-08-29
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-kappa B.
J. Biol. Chem., 293, 2018
6GGR
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CRYSTAL STRUCTURE OF SALMONELLA ZINC METALLOPROTEASE EFFECTOR GTGA IN COMPLEX WITH P65
分子名称:Transcription factor p65, Bacteriophage virulence determinant, CHLORIDE ION
著者Jennings, E., Esposito, D., Rittinger, K., Thurston, T.
登録日2018-05-03
公開日2018-08-29
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Structure-function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-kappa B.
J. Biol. Chem., 293, 2018
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