Author results

2R7C
  • Download 2r7c
  • View 2r7c
Molmil generated image of 2r7c
CRYSTALLOGRAPHIC AND BIOCHEMICAL ANALYSIS OF ROTAVIRUS NSP2 WITH NUCLEOTIDES REVEALS AN NDP KINASE LIKE ACTIVITY
Descriptor:Non-structural RNA-binding protein 35, PHOSPHATE ION
Authors:Kumar, M., Prasad, B.V.V.
Deposit date:2007-09-07
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
J.Virol., 81, 2007
2R7J
  • Download 2r7j
  • View 2r7j
Molmil generated image of 2r7j
CRYSTAL STRUCTURE OF ROTAVIRUS NON STRUCTURAL PROTEIN NSP2 WITH H225A MUTATION
Descriptor:Non-structural RNA-binding protein 35
Authors:Kumar, M., Jayaram, H., Prasad, B.V.V.
Deposit date:2007-09-09
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
J.Virol., 81, 2007
2R7P
  • Download 2r7p
  • View 2r7p
Molmil generated image of 2r7p
CRYSTAL STRUCTURE OF H225A NSP2 AND AMPPNP COMPLEX
Descriptor:Non-structural RNA-binding protein 35, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Kumar, M., Prasad, B.V.V.
Deposit date:2007-09-09
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
J.Virol., 81, 2007
2R8F
  • Download 2r8f
  • View 2r8f
Molmil generated image of 2r8f
CRYSTAL STRUCTURE OF H225A NSP2 AND ATP-GS COMPLEX
Descriptor:Non-structural RNA-binding protein 35, PHOSPHATE ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Kumar, M., Prasad, B.V.V.
Deposit date:2007-09-10
Release date:2007-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity
J.Virol., 81, 2007
2AEN
  • Download 2aen
  • View 2aen
Molmil generated image of 2aen
CRYSTAL STRUCTURE OF THE ROTAVIRUS STRAIN DS-1 VP8* CORE
Descriptor:Outer capsid protein VP4, VP8* core, ETHANOL, ...
Authors:Monnier, N., Higo-Moriguchi, K., Sun, Z.-Y.J., Prasad, B.V.V., Taniguchi, K., Dormitzer, P.R.
Deposit date:2005-07-22
Release date:2006-02-07
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (1.604 Å)
Cite:High-resolution molecular and antigen structure of the VP8* core of a sialic acid-independent human rotavirus strain
J.Virol., 80, 2006
2C86
  • Download 2c86
  • View 2c86
Molmil generated image of 2c86
X-RAY STRUCTURE OF THE N AND C-TERMINAL DOMAIN OF CORONAVIRUS NUCLEOCAPSID PROTEIN.
Descriptor:NUCLEOCAPSID PROTEIN
Authors:Jayaram, H., Fan, H., Bowman, B.R., Ooi, A., Jayaram, J., Collinson, E.W., Lescar, J., Prasad, B.V.V.
Deposit date:2005-12-02
Release date:2006-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-Ray Structures of the N- and C-Terminal Domains of a Coronavirus Nucleocapsid Protein: Implications for Nucleocapsid Formation.
J.Virol., 80, 2006
2CA1
  • Download 2ca1
  • View 2ca1
Molmil generated image of 2ca1
CRYSTAL STRUCTURE OF THE IBV CORONAVIRUS NUCLEOCAPSID
Descriptor:NUCLEOCAPSID PROTEIN
Authors:Jayaram, H., Fan, H., Bowman, B.R., Ooi, A., Jayaram, J., Collison, E.W., Lescar, J., Prasad, B.V.V.
Deposit date:2005-12-16
Release date:2006-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:X-Ray Structures of the N- and C-Terminal Domains of a Coronavirus Nucleocapsid Protein: Implications for Nucleocapsid Formation.
J.Virol., 80, 2006
2GU0
  • Download 2gu0
  • View 2gu0
Molmil generated image of 2gu0
CRYSTAL STRUCTURE OF HUMAN ROTAVIRUS NSP2 (GROUP C / BRISTOL STRAIN)
Descriptor:Nonstructural protein 2
Authors:Jiang, X., Prasad, B.V.V.
Deposit date:2006-04-28
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-function analysis of rotavirus NSP2 octamer by using a novel complementation system
J.Virol., 80, 2006
2ZL5
  • Download 2zl5
  • View 2zl5
Molmil generated image of 2zl5
ATOMIC RESOLUTION STRUCTURAL CHARACTERIZATION OF RECOGNITION OF HISTO-BLOOD GROUP ANTIGEN BY NORWALK VIRUS
Descriptor:58 kd capsid protein, CALCIUM ION, ACETATE ION, ...
Authors:Choi, J.M., Huston, A.M., Estes, M.K., Prasad, B.V.V.
Deposit date:2008-04-02
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus
Proc.Natl.Acad.Sci.Usa, 105, 2008
2ZL6
  • Download 2zl6
  • View 2zl6
Molmil generated image of 2zl6
ATOMIC RESOLUTION STRUCTURAL CHARACTERIZATION OF RECOGNITION OF HISTO-BLOOD GROUP ANTIGENS BY NORWALK VIRUS
Descriptor:58 kd capsid protein, MAGNESIUM ION, ACETATE ION, ...
Authors:Choi, J.M., Huston, A.M., Estes, M.K., Prasad, B.V.V.
Deposit date:2008-04-02
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus
Proc.Natl.Acad.Sci.Usa, 105, 2008
2ZL7
  • Download 2zl7
  • View 2zl7
Molmil generated image of 2zl7
ATOMIC RESOLUTION STRUCTURAL CHARACTERIZATION OF RECOGNITION OF HISTO-BLOOD GROUP ANTIGENS BY NORWALK VIRUS
Descriptor:58 kd capsid protein, CALCIUM ION, MAGNESIUM ION, ...
Authors:Choi, J.M., Huston, A.M., Estes, M.K., Prasad, B.V.V.
Deposit date:2008-04-02
Release date:2008-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus
Proc.Natl.Acad.Sci.Usa, 105, 2008
3F5T
  • Download 3f5t
  • View 3f5t
Molmil generated image of 3f5t
X-RAY STRUCTURE OF H5N1 NS1
Descriptor:Nonstructural protein 1
Authors:Bornholdt, Z.A., Prasad, B.V.V.
Deposit date:2008-11-04
Release date:2008-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus
Nature, 456, 2008
5TW6
  • Download 5tw6
  • View 5tw6
Molmil generated image of 5tw6
CTX-M-14 P167S:E166A MUTANT WITH ACYLATED CEFTAZIDIME MOLECULE
Descriptor:Beta-lactamase, ACYLATED CEFTAZIDIME, 1,2-ETHANEDIOL
Authors:Patel, M., Stojanoski, V., Sankaran, B., Prasad, B.V.V., Palzkill, T.
Deposit date:2016-11-11
Release date:2017-06-28
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M beta-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation.
Biochemistry, 56, 2017
5TWD
  • Download 5twd
  • View 5twd
Molmil generated image of 5twd
CTX-M-14 P167S APOENZYME
Descriptor:Beta-lactamase
Authors:Patel, M., Stojanoski, V., Sankaran, B., Prasad, B.V.V., Palzkill, T.
Deposit date:2016-11-12
Release date:2017-06-28
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M beta-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation.
Biochemistry, 56, 2017
5TWE
  • Download 5twe
  • View 5twe
Molmil generated image of 5twe
CTX-M-14 P167S:S70G MUTANT ENZYME CRYSTALLIZED WITH CEFTAZIDIME
Descriptor:Beta-lactamase, ACYLATED CEFTAZIDIME
Authors:Patel, M., Stojanoski, V., Sankaran, B., Prasad, B.V.V., Palzkill, T.
Deposit date:2016-11-12
Release date:2017-06-28
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M beta-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation.
Biochemistry, 56, 2017
5U53
  • Download 5u53
  • View 5u53
Molmil generated image of 5u53
CTX-M-14 E166A WITH ACYLATED CEFTAZIDIME MOLECULE
Descriptor:Beta-lactamase, ACYLATED CEFTAZIDIME, NITRATE ION
Authors:Patel, M., Stojanoski, V., Sankaran, B., Prasad, B.V.V., Palzkill, T.
Deposit date:2016-12-06
Release date:2017-06-28
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M beta-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation.
Biochemistry, 56, 2017
5VTH
  • Download 5vth
  • View 5vth
Molmil generated image of 5vth
CTX-M-14 P167S:E166A MUTANT
Descriptor:Beta-lactamase
Authors:Hu, L., Patel, M., Prasad, B.V.V., Palzkill, T.
Deposit date:2017-05-17
Release date:2017-06-28
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Drug-Resistant Variant P167S Expands the Substrate Profile of CTX-M beta-Lactamases for Oxyimino-Cephalosporin Antibiotics by Enlarging the Active Site upon Acylation.
Biochemistry, 56, 2017
6CY9
  • Download 6cy9
  • View 6cy9
Molmil generated image of 6cy9
SA11 ROTAVIRUS NSP2 WITH DISULFIDE BRIDGE
Descriptor:Non-structural protein 2, MAGNESIUM ION
Authors:Anish, R., Hu, L., Prasad, B.V.V.
Deposit date:2018-04-05
Release date:2018-12-05
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.615 Å)
Cite:Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CYA
  • Download 6cya
  • View 6cya
Molmil generated image of 6cya
ROTAVIRUS SA11 NSP2 S313A MUTANT
Descriptor:Non-structural protein 2, GLYCEROL, CHLORIDE ION
Authors:Anish, R., Hu, L., Prasad, B.V.V.
Deposit date:2018-04-05
Release date:2018-12-05
Last modified:2019-01-02
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6CYK
  • Download 6cyk
  • View 6cyk
Molmil generated image of 6cyk
CTX-M-14 N106S MUTANT
Descriptor:Beta-lactamase, ACETATE ION
Authors:Patel, M.P., Hu, L., Brown, C., Prasad, B.V.V., Palzkill, T.
Deposit date:2018-04-06
Release date:2018-10-10
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Synergistic effects of functionally distinct substitutions in beta-lactamase variants shed light on the evolution of bacterial drug resistance.
J. Biol. Chem., 293, 2018
6CYN
  • Download 6cyn
  • View 6cyn
Molmil generated image of 6cyn
CTX-M-14 N106S/D240G MUTANT
Descriptor:Beta-lactamase
Authors:Patel, M.P., Hu, L., Browm, C., Prasad, B.V.V., Palzkill, T.
Deposit date:2018-04-06
Release date:2018-10-10
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Synergistic effects of functionally distinct substitutions in beta-lactamase variants shed light on the evolution of bacterial drug resistance.
J. Biol. Chem., 293, 2018
6CYQ
  • Download 6cyq
  • View 6cyq
Molmil generated image of 6cyq
CRYSTAL STRUCTURE OF CTX-M-14 S70G/N106S BETA-LACTAMASE IN COMPLEX WITH HYDROLYZED CEFOTAXIME
Descriptor:Beta-lactamase, (2R)-2-[(R)-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}(carboxy)methyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, GLYCEROL
Authors:Patel, M.P., Hu, L., Brown, C., Prasad, B.V.V., Palzkill, T.
Deposit date:2018-04-06
Release date:2018-10-10
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Synergistic effects of functionally distinct substitutions in beta-lactamase variants shed light on the evolution of bacterial drug resistance.
J. Biol. Chem., 293, 2018
6CYU
  • Download 6cyu
  • View 6cyu
Molmil generated image of 6cyu
CRYSTAL STRUCTURE OF CTX-M-14 S70G/N106S/D240G BETA-LACTAMASE IN COMPLEX WITH HYDROLYZED CEFOTAXIME
Descriptor:Beta-lactamase, (2R)-2-[(R)-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}(carboxy)methyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
Authors:Patel, M.P., Hu, L., Brown, C., Prasad, B.V.V., Palzkill, T.
Deposit date:2018-04-06
Release date:2018-10-10
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Synergistic effects of functionally distinct substitutions in beta-lactamase variants shed light on the evolution of bacterial drug resistance.
J. Biol. Chem., 293, 2018
4IMQ
  • Download 4imq
  • View 4imq
Molmil generated image of 4imq
STRUCTURAL BASIS OF SUBSTRATE SPECIFICITY AND PROTEASE INHIBITION IN NORWALK VIRUS
Descriptor:3C-like protease, PEPTIDE INHIBITOR, syc8, ...
Authors:Prasad, B.V.V., Muhaxhiri, Z., Deng, L., Shanker, S., Sankaran, B., Estes, M.K., Palzkill, T., Song, Y.
Deposit date:2013-01-03
Release date:2013-02-20
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013
4IMZ
  • Download 4imz
  • View 4imz
Molmil generated image of 4imz
STRUCTURAL BASIS OF SUBSTRATE SPECIFICITY AND PROTEASE INHIBITION IN NORWALK VIRUS
Descriptor:Genome polyprotein, peptide inhibitor, syc 10, ...
Authors:Prasad, B.V.V., Muhaxhiri, Z., Deng, L., Shanker, S., Sankaran, B., Estes, M.K., Palzkill, T., Song, Y.
Deposit date:2013-01-03
Release date:2013-02-20
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis of substrate specificity and protease inhibition in norwalk virus.
J.Virol., 87, 2013