2A5R
| Complex of tetra-(4-n-methylpyridyl) porphin with monomeric parallel-stranded DNA tetraplex, snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, C-MYC promoter, NMR, 6 struct. | Descriptor: | (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3' | Authors: | Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J. | Deposit date: | 2005-06-30 | Release date: | 2005-07-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter. Nat.Chem.Biol., 1, 2005
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2A5P
| Monomeric parallel-stranded DNA tetraplex with snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, NMR, 8 struct. | Descriptor: | 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3' | Authors: | Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J. | Deposit date: | 2005-06-30 | Release date: | 2005-07-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter. Nat.Chem.Biol., 1, 2005
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1Y8D
| Dimeric parallel-stranded tetraplex with 3+1 5' G-tetrad interface, single-residue chain reversal loops and GAG triad in the context of A(GGGG) pentad | Descriptor: | 5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*GP*T)-3' | Authors: | Phan, A.T, Kuryavyi, V.V, Ma, J.-B, Faure, A, Andreola, M.-L, Patel, D.J. | Deposit date: | 2004-12-11 | Release date: | 2005-02-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | An interlocked dimeric parallel-stranded DNA quadruplex: A potent inhibitor of HIV-1 integrase Proc.Natl.Acad.Sci.USA, 102, 2005
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1ELN
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1EL2
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2O3M
| Monomeric G-DNA tetraplex from human C-kit promoter | Descriptor: | 5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3' | Authors: | Phan, A.T, Kuryavyi, V.V, Burge, S, Neidle, S, Patel, D.J. | Deposit date: | 2006-12-01 | Release date: | 2007-05-22 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter. J.Am.Chem.Soc., 129, 2007
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6H1K
| The major G-quadruplex form of HIV-1 LTR | Descriptor: | DNA (28-MER) | Authors: | Phan, A.T, Heddi, B, Butovskaya, E, Bakalar, B, Richter, S.N. | Deposit date: | 2018-07-11 | Release date: | 2018-10-17 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop. J. Am. Chem. Soc., 140, 2018
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2JSK
| Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, 16 G Form 1, NMR, 10 Structures | Descriptor: | HUMAN TELOMERE DNA | Authors: | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | Deposit date: | 2007-07-07 | Release date: | 2008-07-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
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2JSL
| Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 Natural, NMR, 10 Structures | Descriptor: | HUMAN TELOMERE DNA | Authors: | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | Deposit date: | 2007-07-08 | Release date: | 2008-07-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
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2JSQ
| Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 15BrG, NMR, 10 Structures | Descriptor: | HUMAN TELOMERE DNA | Authors: | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | Deposit date: | 2007-07-11 | Release date: | 2008-07-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
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2JSM
| MONOMERIC HUMAN TELOMERE DNA TETRAPLEX WITH 3+1 STRAND FOLD TOPOLOGY, TWO EDGEWISE LOOPS AND DOUBLE-CHAIN REVERSAL LOOP, NMR, 10 STRUCTURES, Form 1 Natural | Descriptor: | HUMAN TELOMERE DNA | Authors: | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | Deposit date: | 2007-07-09 | Release date: | 2008-07-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution Nucleic Acids Res., 35, 2007
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2KBP
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8IPP
| Crystal structure of the complex between an ankyrin and a parallel G-quadruplex | Descriptor: | 93del-T12, DARPin protein 2E4, MAGNESIUM ION, ... | Authors: | Ngo, K.H, Liew, C.W, Heddi, B, Phan, A.T. | Deposit date: | 2023-03-14 | Release date: | 2024-07-31 | Method: | X-RAY DIFFRACTION (2.007 Å) | Cite: | Structural Basis for Parallel G-Quadruplex Recognition by an Ankyrin Protein. J.Am.Chem.Soc., 146, 2024
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8IPF
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6Q6R
| Recognition of different base tetrads by RHAU: X-ray crystal structure of G4 recognition motif bound to the 3-end tetrad of a DNA G-quadruplex | Descriptor: | ATP-dependent DNA/RNA helicase DHX36, POTASSIUM ION, Parallel stranded DNA G-quadruplex | Authors: | Heddi, B, Cheong, V.V, Schmitt, E, Mechulam, Y, Phan, A.T. | Deposit date: | 2018-12-11 | Release date: | 2019-10-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Recognition of different base tetrads by RHAU (DHX36): X-ray crystal structure of the G4 recognition motif bound to the 3'-end tetrad of a DNA G-quadruplex. J.Struct.Biol., 209, 2020
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6QJO
| DNA containing both right- and left-handed parallel-stranded G-quadruplexes | Descriptor: | DNA (28-MER), POTASSIUM ION | Authors: | Winnerdy, F.R, Bakalar, B, Maity, A, Vandana, J.J, Schmitt, E, Mechulam, Y, Phan, A.T. | Deposit date: | 2019-01-24 | Release date: | 2019-07-03 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | NMR solution and X-ray crystal structures of a DNA molecule containing both right- and left-handed parallel-stranded G-quadruplexes. Nucleic Acids Res., 47, 2019
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7CV4
| Quadruplex-duplex hybrid structure in the PIM1 gene, Form 2 | Descriptor: | DNA (26-MER) | Authors: | Winnerdy, F.R, Tan, D.T.J, Lim, K.W, Phan, A.T. | Deposit date: | 2020-08-25 | Release date: | 2020-10-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Coexistence of two quadruplex-duplex hybrids in the PIM1 gene. Nucleic Acids Res., 48, 2020
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7CUK
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7DFY
| Novel motif for left-handed G-quadruplex formation | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2xMotif2, POTASSIUM ION, ... | Authors: | Das, P, Winnerdy, F.R, Maity, A, Mechulam, Y, Phan, A.T. | Deposit date: | 2020-11-10 | Release date: | 2021-09-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | A novel minimal motif for left-handed G-quadruplex formation. Chem.Commun.(Camb.), 57, 2021
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7CV3
| Quadruplex-duplex hybrid structure in the PIM1 gene, Form 1 | Descriptor: | PIM1 promoter, Form 1 | Authors: | Winnerdy, F.R, Tan, D.J.Y, Lim, K.W, Phan, A.T. | Deposit date: | 2020-08-25 | Release date: | 2020-10-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Coexistence of two quadruplex-duplex hybrids in the PIM1 gene. Nucleic Acids Res., 48, 2020
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7CLS
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7D5D
| Left-handed G-quadruplex containing one bulge | Descriptor: | 1xBulge-LHG4motif, POTASSIUM ION, SPERMINE | Authors: | Das, P, Ngo, K.H, Winnerdy, F.R, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | Deposit date: | 2020-09-25 | Release date: | 2021-02-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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7D5E
| Left-handed G-quadruplex containing two bulges | Descriptor: | 2xBulge-LHG4motif, POTASSIUM ION, SODIUM ION, ... | Authors: | Das, P, Maity, A, Ngo, K.H, Winnerdy, F.R, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | Deposit date: | 2020-09-25 | Release date: | 2021-02-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.296 Å) | Cite: | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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7D5F
| Left-handed G-quadruplex containing 3 bulges | Descriptor: | 3xBulge-LHG4motif | Authors: | Winnerdy, F.R, Das, P, Ngo, K.H, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | Deposit date: | 2020-09-25 | Release date: | 2021-02-10 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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2KF8
| Structure of a two-G-tetrad basket-type intramolecular G-quadruplex formed by human telomeric repeats in K+ solution | Descriptor: | HUMAN TELOMERE DNA | Authors: | Lim, K.W, Amrane, S, Bouaziz, S, Xu, W, Mu, Y, Patel, D.J, Luu, K.N, Phan, A.T. | Deposit date: | 2009-02-12 | Release date: | 2009-03-24 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of the human telomere in K+ solution: a stable basket-type G-quadruplex with only two G-tetrad layers J.Am.Chem.Soc., 131, 2009
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