1ZBF | | CRYSTAL STRUCTURE OF B. HALODURANS RNASE H CATALYTIC DOMAIN MUTANT D132N | | Descriptor: | ribonuclease H-related protein, SULFATE ION | | Authors: | Nowotny, M., Gaidamakov, S.A., Crouch, R.J., Yang, W. | | Deposit date: | 2005-04-08 | | Release date: | 2005-07-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
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1ZBI | | BACILLUS HALODURANS RNASE H CATALYTIC DOMAIN MUTANT D132N IN COMPLEX WITH 12-MER RNA/DNA HYBRID | | Descriptor: | 5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3', 5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3', ribonuclease H-related protein, ... | | Authors: | Nowotny, M., Gaidamakov, S.A., Crouch, R.J., Yang, W. | | Deposit date: | 2005-04-08 | | Release date: | 2005-07-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
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1ZBL | | BACILLUS HALODURANS RNASE H CATALYTIC DOMAIN MUTANT D192N IN COMPLEX WITH 12-MER RNA/DNA HYBRID | | Descriptor: | 5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3', 5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3', ribonuclease H-related protein, ... | | Authors: | Nowotny, M., Gaidamakov, S.A., Crouch, R.J., Yang, W. | | Deposit date: | 2005-04-08 | | Release date: | 2005-07-12 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
Cell(Cambridge,Mass.), 121, 2005
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2G8F | |
2G8H | |
2G8I | |
2G8K | |
2G8U | |
2G8V | |
2G8W | |
2QK9 | | HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 18-MER RNA/DNA HYBRID | | Descriptor: | 5'-R(*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*T)-3', Ribonuclease H1, ... | | Authors: | Nowotny, M., Gaidamakov, S.A., Ghirlando, R., Cerritelli, S.M., Crouch, R.J., Yang, W. | | Deposit date: | 2007-07-10 | | Release date: | 2007-11-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
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2QKB | | HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 20-MER RNA/DNA HYBRID | | Descriptor: | 5'-R(*GP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3'), 5'-D(*DGP*DGP*DAP*DAP*DTP*DCP*DAP*DGP*DGP*DTP*DGP*DTP*DCP*DGP*DCP*DAP*DCP*DTP*DCP*DT)-3', Ribonuclease H1, ... | | Authors: | Nowotny, M., Gaidamakov, S.A., Ghirlando, R., Cerritelli, S.M., Crouch, R.J., Yang, W. | | Deposit date: | 2007-07-10 | | Release date: | 2007-11-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
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2QKK | | HUMAN RNASE H CATALYTIC DOMAIN MUTANT D210N IN COMPLEX WITH 14-MER RNA/DNA HYBRID | | Descriptor: | 5'-R(*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*G)-3', Ribonuclease H1, ... | | Authors: | Nowotny, M., Gaidamakov, S.A., Ghirlando, R., Cerritelli, S.M., Crouch, R.J., Yang, W. | | Deposit date: | 2007-07-11 | | Release date: | 2007-11-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription
Mol.Cell, 28, 2007
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3BSU | | HYBRID-BINDING DOMAIN OF HUMAN RNASE H1 IN COMPLEX WITH 12-MER RNA/DNA | | Descriptor: | RNA (5'-R(*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*C)-3'), DNA (5'-D(*DGP*DAP*DAP*DTP*DCP*DAP*DGP*DGP*(5IU)P*DGP*DTP*DC)-3'), Ribonuclease H1, ... | | Authors: | Nowotny, M., Cerritelli, S.M., Ghirlando, R., Gaidamakov, S.A., Crouch, R.J., Yang, W. | | Deposit date: | 2007-12-26 | | Release date: | 2008-03-25 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD.
Embo J., 27, 2008
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6F3H | | CRYSTAL STRUCTURE OF DSS1 EXORIBONUCLEASE ACTIVE SITE MUTANT D477N FROM CANDIDA GLABRATA | | Descriptor: | Exoribonuclease II, mitochondrial, RNA (5'-R(P*AP*GP*AP*UP*AP*C)-3'), ... | | Authors: | Razew, M., Nowak, E., Nowotny, M. | | Deposit date: | 2017-11-28 | | Release date: | 2018-01-17 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.
Nat Commun, 9, 2018
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6F4A | | YEAST MITOCHONDRIAL RNA DEGRADOSOME COMPLEX MTEXO | | Descriptor: | Exoribonuclease II, mitochondrial, Suv3 helicase, ... | | Authors: | Razew, M., Nowak, E., Nowotny, M. | | Deposit date: | 2017-11-29 | | Release date: | 2018-01-17 | | Method: | X-RAY DIFFRACTION (3.55 Å) | | Cite: | Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components.
Nat Commun, 9, 2018
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3PIH | | T. MARITIMA UVRA IN COMPLEX WITH FLUORESCEIN-MODIFIED DNA | | Descriptor: | UvrABC system protein A, DNA (32-MER), PYROPHOSPHATE, ... | | Authors: | Jaciuk, M., Nowak, E., Nowotny, M. | | Deposit date: | 2010-11-06 | | Release date: | 2011-01-19 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of UvrA nucleotide excision repair protein in complex with modified DNA.
Nat.Struct.Mol.Biol., 18, 2011
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3PUF | | CRYSTAL STRUCTURE OF HUMAN RNASE H2 COMPLEX | | Descriptor: | Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C | | Authors: | Figiel, M., Chon, H., Cerritelli, S.M., Cybulska, M., Crouch, R.J., Nowotny, M. | | Deposit date: | 2010-12-04 | | Release date: | 2010-12-22 | | Last modified: | 2012-08-29 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutieres syndrome defects.
J.Biol.Chem., 286, 2011
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4HHT | |
4N48 | | CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 PROTEIN IN COMPLEX WITH CAPPED RNA FRAGMENT | | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, capped RNA, S-ADENOSYLMETHIONINE, ... | | Authors: | Smietanski, M., Werener, M., Purta, E., Kaminska, K.H., Stepinski, J., Darzynkiewicz, E., Nowotny, M., Bujnicki, J.M. | | Deposit date: | 2013-10-08 | | Release date: | 2014-01-22 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (2.704 Å) | | Cite: | Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.
Nat Commun, 5, 2014
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4N49 | | CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 PROTEIN IN COMPLEX WITH M7GPPPG AND SAM | | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, S-ADENOSYLMETHIONINE, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Smietanski, M., Werener, M., Purta, E., Kaminska, K.H., Stepinski, J., Darzynkiewicz, E., Nowotny, M., Bujnicki, J.M. | | Deposit date: | 2013-10-08 | | Release date: | 2014-01-22 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.
Nat Commun, 5, 2014
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4N4A | | CYSTAL STRUCTURE OF CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 | | Descriptor: | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 | | Authors: | Smietanski, M., Werener, M., Purta, E., Kaminska, K.H., Stepinski, J., Darzynkiewicz, E., Nowotny, M., Bujnicki, J.M. | | Deposit date: | 2013-10-08 | | Release date: | 2014-01-22 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.
Nat Commun, 5, 2014
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4PY5 | | THERMOVIBRIO AMMONIFICANS RNASE H3 IN COMPLEX WITH 19-MER RNA/DNA | | Descriptor: | Ribonuclease, 5'-R(*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*TP*C)-3', ... | | Authors: | Figiel, M., Nowotny, M. | | Deposit date: | 2014-03-26 | | Release date: | 2014-07-30 | | Last modified: | 2014-10-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of RNase H3-substrate complex reveals parallel evolution of RNA/DNA hybrid recognition.
Nucleic Acids Res., 42, 2014
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4Q0R | | THE CATALYTIC CORE OF RAD2 (COMPLEX I) | | Descriptor: | DNA repair protein RAD2, DNA (5'-D(*CP*TP*GP*AP*GP*TP*CP*AP*GP*AP*GP*CP*AP*AP*A)-3') | | Authors: | Mietus, M., Nowak, E., Jaciuk, M., Kustosz, P., Nowotny, M. | | Deposit date: | 2014-04-02 | | Release date: | 2014-08-27 | | Last modified: | 2017-08-09 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Crystal structure of the catalytic core of Rad2: insights into the mechanism of substrate binding.
Nucleic Acids Res., 42, 2014
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4Q0W | | HE CATALYTIC CORE OF RAD2 IN COMPLEX WITH DNA SUBSTRATE (COMPLEX II) | | Descriptor: | DNA repair protein RAD2, DNA (5'-D(*TP*TP*TP*GP*AP*TP*CP*CP*GP*TP*CP*CP*AP*CP*CP*TP*TP*T)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*TP*GP*GP*AP*CP*GP*GP*AP*TP*CP*AP*TP*T)-3'), ... | | Authors: | Mietus, M., Nowak, E., Jaciuk, M., Kustosz, P., Nowotny, M. | | Deposit date: | 2014-04-02 | | Release date: | 2014-08-27 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of the catalytic core of Rad2: insights into the mechanism of substrate binding.
Nucleic Acids Res., 42, 2014
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