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3WIH
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CRYSTAL STRUCTURE OF THE THIRD FIBRONECTIN DOMAIN (FN3) OF HUMAN ROBO1 IN COMPLEX WITH THE FAB FRAGMENT OF MURINE MONOCLONAL ANTIBODY B2212A.
Descriptor:Roundabout homolog 1, anti-human ROBO1 antibody B2212A Fab light chain, anti-human ROBO1 antibody B2212A Fab heavy chain, ...
Authors:Nakayama, T., Mizohata, E., Yamashita, T., Nagatoishi, M., Iwanari, H., Mochizuki, Y., Kado, Y., Yokota, Y., Sato, R., Tsumoto, K., Fujitani, H., Kodama, T., Hamakubo, T., Inoue, T.
Deposit date:2013-09-12
Release date:2015-01-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses
Protein Sci., 24, 2015
3WII
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CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF B2212A, A MURINE MONOCLONAL ANTIBODY SPECIFIC FOR THE THIRD FIBRONECTIN DOMAIN (FN3) OF HUMAN ROBO1.
Descriptor:anti-human ROBO1 antibody B2212A Fab light chain, anti-human ROBO1 antibody B2212A Fab heavy chain
Authors:Nakayama, T., Mizohata, E., Yamashita, T., Nagatoishi, S., Nakakido, M., Iwanari, H., Mochizuki, Y., Kado, Y., Yokota, Y., Sato, R., Tsumoto, K., Fujitani, H., Kodama, T., Hamakubo, T., Inoue, T.
Deposit date:2013-09-12
Release date:2015-01-21
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural features of interfacial tyrosine residue in ROBO1 fibronectin domain-antibody complex: Crystallographic, thermodynamic, and molecular dynamic analyses
Protein Sci., 24, 2015
1ZVJ
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STRUCTURE OF KUMAMOLISIN-AS MUTANT, D164N
Descriptor:kumamolisin-As, CALCIUM ION, SULFATE ION
Authors:Li, M., Wlodawer, A., Gustchina, A., Nakayama, T.
Deposit date:2005-06-02
Release date:2006-05-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Processing, catalytic activity and crystal structures of kumamolisin-As with an engineered active site.
Febs J., 273, 2006
1ZVK
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STRUCTURE OF DOUBLE MUTANT, D164N, E78H OF KUMAMOLISIN-AS
Descriptor:kumamolisin-As, CALCIUM ION
Authors:Li, M., Wlodawer, A., Gustchina, A., Nakayama, T.
Deposit date:2005-06-02
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Processing, catalytic activity and crystal structures of kumamolisin-As with an engineered active site.
Febs J., 273, 2006
5AZ2
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CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF 9E5, A MURINE MONOCLONAL ANTIBODY SPECIFIC FOR HUMAN EPIREGULIN
Descriptor:anti-human epiregulin antibody 9E5 Fab heavy chain, anti-human epiregulin antibody 9E5 Fab light chain
Authors:Kado, Y., Mizohata, E., Nagatoishi, S., Iijima, M., Shinoda, K., Miyafusa, T., Nakayama, T., Yoshizumi, T., Sugiyama, A., Kawamura, T., Lee, Y.H., Matsumura, H., Doi, H., Fujitani, H., Kodama, T., Shibasaki, Y., Tsumoto, K., Inoue, T.
Deposit date:2015-09-16
Release date:2015-12-09
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES
J.Biol.Chem., 291, 2016
5E8D
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CRYSTAL STRUCTURE OF HUMAN EPIREGULIN IN COMPLEX WITH THE FAB FRAGMENT OF MURINE MONOCLONAL ANTIBODY 9E5
Descriptor:Proepiregulin, anti-human epiregulin antibody 9E5 Fab heavy chain, anti-human epiregulin antibody 9E5 Fab light chain, ...
Authors:Kado, Y., Mizohata, E., Nagatoishi, S., Iijima, M., Shinoda, K., Miyafusa, T., Nakayama, T., Yoshizumi, T., Sugiyama, A., Kawamura, T., Lee, Y.H., Matsumura, H., Doi, H., Fujitani, H., Kodama, T., Shibasaki, Y., Tsumoto, K., Inoue, T.
Deposit date:2015-10-14
Release date:2015-12-09
Last modified:2016-02-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Epiregulin Recognition Mechanisms by Anti-epiregulin Antibody 9E5: STRUCTURAL, FUNCTIONAL, AND MOLECULAR DYNAMICS SIMULATION ANALYSES
J.Biol.Chem., 291, 2016
6A76
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CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF B5209B, A MURINE MONOCLONAL ANTIBODY SPECIFIC FOR THE FIFTH IMMUNOGLOBULIN DOMAIN (IG5) OF HUMAN ROBO1
Descriptor:Light chain of the anti-human Robo1 antibody B5209B Fab, Heavy chain of the anti-human Robo1 antibody B5209B Fab, GLYCEROL, ...
Authors:Mizohata, E., Nakayama, T., Kado, Y., Inoue, T.
Deposit date:2018-07-02
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
6A77
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CRYSTAL STRUCTURE OF THE FIFTH IMMUNOGLOBULIN DOMAIN (IG5) OF HUMAN ROBO1 IN COMPLEX WITH THE FAB FRAGMENT OF MURINE MONOCLONAL ANTIBODY B5209B
Descriptor:Roundabout homolog 1, Light chain of the anti-human Robo1 antibody B5209B Fab, Heavy chain of the anti-human Robo1 antibody B5209B Fab
Authors:Mizohata, E., Nakayama, T., Kado, Y., Inoue, T.
Deposit date:2018-07-02
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
6A78
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CRYSTAL STRUCTURE OF THE FIFTH IMMUNOGLOBULIN DOMAIN (IG5) OF HUMAN ROBO1 IN COMPLEX WITH THE SCFV FRAGMENT OF MURINE MONOCLONAL ANTIBODY B5209B
Descriptor:Roundabout homolog 1, Light chain region of the anti-human Robo1 antibody B5209B scFv, Heavy chain and linker region of the anti-human Robo1 antibody B5209B scFv, ...
Authors:Mizohata, E., Nakayama, T., Kado, Y., Inoue, T.
Deposit date:2018-07-02
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
6A79
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CRYSTAL STRUCTURE OF THE FIFTH IMMUNOGLOBULIN DOMAIN (IG5) OF HUMAN ROBO1 IN COMPLEX WITH THE MUTANT SCFV FRAGMENT (P103A) OF MURINE MONOCLONAL ANTIBODY B5209B
Descriptor:Roundabout homolog 1, Light chain region of the anti-human Robo1 antibody B5209B scFv, Heavy chain of the anti-human Robo1 antibody B5209B scFv, ...
Authors:Mizohata, E., Nakayama, T., Kado, Y., Yokota, Y., Inoue, T.
Deposit date:2018-07-02
Release date:2019-01-30
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface.
Structure, 27, 2019
2ZRU
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CRYSTAL STRUCTURE OF SULFOLOBUS SHIBATAE ISOPENTENYL DIPHOSPHATE ISOMERASE IN COMPLEX WITH FMN
Descriptor:Isopentenyl-diphosphate delta-isomerase, FLAVIN MONONUCLEOTIDE
Authors:Unno, H., Yamashita, S., Ikeda, Y., Sekiguchi, S., Yoshida, N., Yoshimura, T., Kusunoki, M., Nakayama, T., Nishino, T., Hemmi, H.
Deposit date:2008-09-01
Release date:2009-01-20
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
2ZRV
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CRYSTAL STRUCTURE OF SULFOLOBUS SHIBATAE ISOPENTENYL DIPHOSPHATE ISOMERASE IN COMPLEX WITH REDUCED FMN.
Descriptor:Isopentenyl-diphosphate delta-isomerase, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL
Authors:Unno, H., Yamashita, S., Ikeda, Y., Sekiguchi, S., Yoshida, N., Yoshimura, T., Kusunoki, M., Nakayama, T., Nishino, T., Hemmi, H.
Deposit date:2008-09-01
Release date:2009-01-20
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
2ZRW
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CRYSTAL STRUCTURE OF SULFOLOBUS SHIBATAE ISOPENTENYL DIPHOSPHATE ISOMERASE IN COMPLEX WITH FMN AND IPP.
Descriptor:Isopentenyl-diphosphate delta-isomerase, FLAVIN MONONUCLEOTIDE, ISOPENTYL PYROPHOSPHATE, ...
Authors:Unno, H., Yamashita, S., Ikeda, Y., Sekiguchi, S., Yoshida, N., Yoshimura, T., Kusunoki, M., Nakayama, T., Nishino, T., Hemmi, H.
Deposit date:2008-09-01
Release date:2009-01-20
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
2ZRX
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CRYSTAL STRUCTURE OF SULFOLOBUS SHIBATAE ISOPENTENYL DIPHOSPHATE ISOMERASE IN COMPLEX WITH FMN AND DMAPP.
Descriptor:Isopentenyl-diphosphate delta-isomerase, FLAVIN MONONUCLEOTIDE, DIMETHYLALLYL DIPHOSPHATE, ...
Authors:Unno, H., Yamashita, S., Ikeda, Y., Sekiguchi, S., Yoshida, N., Yoshimura, T., Kusunoki, M., Nakayama, T., Nishino, T., Hemmi, H.
Deposit date:2008-09-01
Release date:2009-01-20
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
2ZRY
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CRYSTAL STRUCTURE OF SULFOLOBUS SHIBATAE ISOPENTENYL DIPHOSPHATE ISOMERASE IN COMPLEX WITH REDUCED FMN AND IPP.
Descriptor:Isopentenyl-diphosphate delta-isomerase, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ...
Authors:Unno, H., Yamashita, S., Ikeda, Y., Sekiguchi, S., Yoshida, N., Yoshimura, T., Kusunoki, M., Nakayama, T., Nishino, T., Hemmi, H.
Deposit date:2008-09-01
Release date:2009-01-20
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
2ZRZ
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CRYSTAL STRUCTURE OF SULFOLOBUS SHIBATAE ISOPENTENYL DIPHOSPHATE ISOMERASE IN COMPLEX WITH REDUCED FMN AND DMAPP
Descriptor:Isopentenyl-diphosphate delta-isomerase, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, DIMETHYLALLYL DIPHOSPHATE, ...
Authors:Unno, H., Yamashita, S., Ikeda, Y., Sekiguchi, S., Yoshida, N., Yoshimura, T., Kusunoki, M., Nakayama, T., Nishino, T., Hemmi, H.
Deposit date:2008-09-01
Release date:2009-01-20
Last modified:2012-05-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:New role of flavin as a general acid-base catalyst with no redox function in type 2 isopentenyl-diphosphate isomerase.
J.Biol.Chem., 284, 2009
5B2C
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CRYSTAL STRUCTURE OF MUMPS VIRUS HEMAGGLUTININ-NEURAMINIDASE
Descriptor:HN protein, N-ACETYL-D-GLUCOSAMINE, SULFATE ION
Authors:Kubota, M., Takeuchi, K., Watanabe, S., Ohno, S., Matsuoka, R., Kohda, D., Hiramatsu, H., Suzuki, Y., Nakayama, T., Terada, T., Shimizu, K., Shimizu, N., Yanagi, Y., Hashiguchi, T.
Deposit date:2016-01-14
Release date:2016-09-28
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.238 Å)
Cite:Trisaccharide containing alpha 2,3-linked sialic acid is a receptor for mumps virus
Proc.Natl.Acad.Sci.USA, 113, 2016
5B2D
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CRYSTAL STRUCTURE OF MUMPS VIRUS HEMAGGLUTININ-NEURAMINIDASE BOUND TO 3-SIALYLLACTOSE
Descriptor:HN protein, N-ACETYL-D-GLUCOSAMINE, 5-(ACETYLAMINO)-3,5-DIDEOXYNON-2-ULOPYRANONOSYL-(2->3)-BETA-D-LYXO-HEXOPYRANOSYL-(1->4)HEXOPYRANOSE, ...
Authors:Kubota, M., Takeuchi, K., Watanabe, S., Ohno, S., Matsuoka, R., Kohda, D., Hiramatsu, H., Suzuki, Y., Nakayama, T., Terada, T., Shimizu, K., Shimizu, N., Yanagi, Y., Hashiguchi, T.
Deposit date:2016-01-14
Release date:2016-09-28
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.177 Å)
Cite:Trisaccharide containing alpha 2,3-linked sialic acid is a receptor for mumps virus
Proc.Natl.Acad.Sci.USA, 113, 2016
1SIO
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STRUCTURE OF KUMAMOLISIN-AS COMPLEXED WITH A COVALENTLY-BOUND INHIBITOR, ACIPF
Descriptor:kumamolisin-As, Ace-ILE-PRO-PHL peptide inhibitor, SULFATE ION, ...
Authors:Li, M., Wlodawer, A., Gustchina, A., Tsuruoka, N., Ashida, M., Minakata, H., Oyama, H., Oda, K., Nishino, T., Nakayama, T.
Deposit date:2004-03-01
Release date:2004-03-30
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity
J.Biol.Chem., 279, 2004
1SIU
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KUMAMOLISIN-AS E78H MUTANT
Descriptor:kumamolisin-As, SULFATE ION, CALCIUM ION
Authors:Li, M., Wlodawer, A., Gustchina, A., Tsuruoka, N., Ashida, M., Minakata, H., Oyama, H., Oda, K., Nishino, T., Nakayama, T.
Deposit date:2004-03-01
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Crystallographic and biochemical investigations of kumamolisin-As, a serine-carboxyl peptidase with collagenase activity
J.Biol.Chem., 279, 2004
2E1T
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CRYSTAL STRUCTURE OF DENDRANTHEMA MORIFOLIUM DMAT COMPLEXED WITH MALONYL-COA
Descriptor:acyl transferase, MALONYL-COENZYME A
Authors:Unno, H., Ichimaida, F., Kusunoki, M., Nakayama, T.
Deposit date:2006-10-28
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mutational Studies of Anthocyanin Malonyltransferases Establish the Features of BAHD Enzyme Catalysis
J.Biol.Chem., 282, 2007
2E1U
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CRYSTAL STRUCTURE OF DENDRANTHEMA MORIFOLIUM DMAT
Descriptor:acyl transferase
Authors:Unno, H., Ichimaida, F., Kusunoki, M., Nakayama, T.
Deposit date:2006-10-28
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and Mutational Studies of Anthocyanin Malonyltransferases Establish the Features of BAHD Enzyme Catalysis
J.Biol.Chem., 282, 2007
2E1V
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CRYSTAL STRUCTURE OF DENDRANTHEMA MORIFOLIUM DMAT, SELENO-METHIONINE DERIVATIVE
Descriptor:acyl transferase
Authors:Unno, H., Ichimaida, F., Kusunoki, M., Nakayama, T.
Deposit date:2006-10-28
Release date:2007-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Mutational Studies of Anthocyanin Malonyltransferases Establish the Features of BAHD Enzyme Catalysis
J.Biol.Chem., 282, 2007
3WJ1
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CRYSTAL STRUCTURE OF SSHESTI
Descriptor:Carboxylesterase, B-OCTYLGLUCOSIDE
Authors:Ohara, K., Unno, H., Oshima, Y., Furukawa, K., Fujino, N., Hirooka, K., Hemmi, H., Takahashi, S., Nishino, T., Kusunoki, M., Nakayama, T.
Deposit date:2013-10-03
Release date:2014-07-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Insights into the Low-pH Adaptation of a Unique Carboxylesterase from Ferroplasma: Altering the pH Optima of Two Carboxylesterases
J.Biol.Chem., 2014
3WJ2
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CRYSTAL STRUCTURE OF ESTFA (FE-LACKING APO FORM)
Descriptor:Carboxylesterase
Authors:Ohara, K., Unno, H., Oshima, Y., Furukawa, K., Fujino, N., Hirooka, K., Hemmi, H., Takahashi, S., Nishino, T., Kusunoki, M., Nakayama, T.
Deposit date:2013-10-03
Release date:2014-07-30
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural Insights into the Low-pH Adaptation of a Unique Carboxylesterase from Ferroplasma: Altering the pH Optima of Two Carboxylesterases
J.Biol.Chem., 2014
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