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3O41
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CRYSTAL STRUCTURE OF 101F FAB BOUND TO 15-MER PEPTIDE EPITOPE
Descriptor:Mouse monoclonal antibody 101F Fab light chain, Mouse monoclonal antibody 101F Fab heavy chain, Fusion glycoprotein F1, ...
Authors:McLellan, J.S., Chen, M., Chang, J.S., Yang, Y., Kim, A., Graham, B.S., Kwong, P.D.
Deposit date:2010-07-26
Release date:2010-10-13
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F.
J.Virol., 84, 2010
3O45
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CRYSTAL STRUCTURE OF 101F FAB BOUND TO 17-MER PEPTIDE EPITOPE
Descriptor:Mouse monoclonal antibody 101F 101F Fab light chain, Mouse monoclonal antibody 101F 101F Fab heavy chain, Fusion glycoprotein F1, ...
Authors:McLellan, J.S., Chen, M., Chang, J.S., Yang, Y., Kim, A., Graham, B.S., Kwong, P.D.
Deposit date:2010-07-26
Release date:2010-10-13
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.872 Å)
Cite:Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F.
J.Virol., 84, 2010
2IBB
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CRYSTAL STRUCTURE OF THE FIRST AND SECOND FNIII DOMAINS OF IHOG
Descriptor:CG9211-PA, SULFATE ION
Authors:McLellan, J.S., Leahy, D.J.
Deposit date:2006-09-11
Release date:2006-10-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2IBG
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CRYSTAL STRUCTURE OF HEDGEHOG BOUND TO THE FNIII DOMAINS OF IHOG
Descriptor:CG9211-PA, Protein hedgehog, PHOSPHATE ION
Authors:McLellan, J.S., Leahy, D.J.
Deposit date:2006-09-11
Release date:2006-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2IC2
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CRYSTAL STRUCTURE OF THE FIRST FNIII DOMAIN OF IHOG
Descriptor:CG9211-PA, SULFATE ION
Authors:McLellan, J.S., Leahy, D.J.
Deposit date:2006-09-12
Release date:2006-10-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of a heparin-dependent complex of Hedgehog and Ihog.
Proc.Natl.Acad.Sci.Usa, 103, 2006
3D1M
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CRYSTAL STRUCTURE OF SONIC HEDGEHOG BOUND TO THE THIRD FNIII DOMAIN OF CDO
Descriptor:Sonic hedgehog protein, Cell adhesion molecule, ZINC ION, ...
Authors:McLellan, J.S., Leahy, D.J.
Deposit date:2008-05-06
Release date:2008-09-23
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla.
Nature, 455, 2008
3IXT
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CRYSTAL STRUCTURE OF MOTAVIZUMAB FAB BOUND TO PEPTIDE EPITOPE
Descriptor:Motavizumab Fab light chain, Motavizumab Fab heavy chain, Fusion glycoprotein F1, ...
Authors:McLellan, J.S., Chen, M., Kim, A., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2009-09-04
Release date:2010-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis of respiratory syncytial virus neutralization by motavizumab.
Nat.Struct.Mol.Biol., 17, 2010
3QWO
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CRYSTAL STRUCTURE OF A MOTAVIZUMAB EPITOPE-SCAFFOLD BOUND TO MOTAVIZUMAB FAB
Descriptor:motavizumab light chain, motavizumab heavy chain, motavizumab epitope scaffold, ...
Authors:McLellan, J.S., Kwong, P.D.
Deposit date:2011-02-28
Release date:2011-05-04
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus.
J.Mol.Biol., 409, 2011
3RRR
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STRUCTURE OF THE RSV F PROTEIN IN THE POST-FUSION CONFORMATION
Descriptor:Fusion glycoprotein F0, N-ACETYL-D-GLUCOSAMINE
Authors:McLellan, J.S., Yongping, Y., Graham, B.S., Kwong, P.D.
Deposit date:2011-04-30
Release date:2011-06-08
Last modified:2014-04-02
Method:X-RAY DIFFRACTION (2.821 Å)
Cite:Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
J.Virol., 85, 2011
3RRT
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STRUCTURE OF THE RSV F PROTEIN IN THE POST-FUSION CONFORMATION
Descriptor:Fusion glycoprotein F0
Authors:McLellan, J.S., Yongping, Y., Graham, B.S., Kwong, P.D.
Deposit date:2011-04-30
Release date:2011-06-08
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of respiratory syncytial virus fusion glycoprotein in the postfusion conformation reveals preservation of neutralizing epitopes.
J.Virol., 85, 2011
3U2S
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CRYSTAL STRUCTURE OF PG9 FAB IN COMPLEX WITH V1V2 REGION FROM HIV-1 STRAIN ZM109
Descriptor:PG9 heavy chain, PG9 light chain, Envelope glycoprotein gp120, ...
Authors:McLellan, J.S., Pancera, M., Kwong, P.D.
Deposit date:2011-10-04
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U36
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CRYSTAL STRUCTURE OF PG9 FAB
Descriptor:PG9 Fab heavy chain, PG9 Fab light chain, SULFATE ION
Authors:McLellan, J.S., Kwong, P.D.
Deposit date:2011-10-04
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (3.281 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
4JHA
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CRYSTAL STRUCTURE OF RSV-NEUTRALIZING HUMAN ANTIBODY D25
Descriptor:D25 antigen-binding fragment heavy chain, D25 light chain
Authors:Mclellan, J.S., Chen, M., Leung, S., Graepel, K.W., Du, X., Yang, Y., Zhou, T., Baxa, U., Yasuda, E., Beaumont, T., Kumar, A., Modjarrad, K., Zheng, Z., Zhao, M., Xia, N., Kwong, P.D., Graham, B.S.
Deposit date:2013-03-04
Release date:2013-05-01
Last modified:2013-06-12
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
4JHW
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CRYSTAL STRUCTURE OF RESPIRATORY SYNCYTIAL VIRUS FUSION GLYCOPROTEIN STABILIZED IN THE PREFUSION CONFORMATION BY HUMAN ANTIBODY D25
Descriptor:D25 antigen-binding fragment heavy chain, D25 light chain, Fusion glycoprotein F0
Authors:Mclellan, J.S., Chen, M., Leung, S., Graepel, K.W., Du, X., Yang, Y., Zhou, T., Baxa, U., Yasuda, E., Beaumont, T., Kumar, A., Modjarrad, K., Zheng, Z., Zhao, M., Xia, N., Kwong, P.D., Graham, B.S.
Deposit date:2013-03-05
Release date:2013-05-01
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody.
Science, 340, 2013
4MMQ
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT DS
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain, SULFATE ION
Authors:Mclellan, J.S., Joyce, M.G., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.253 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMS
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT CAV1 AT PH 5.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain, SULFATE ION
Authors:Mclellan, J.S., Joyce, M.G., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.397 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4R4B
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CRYSTAL STRUCTURE OF THE ANTI-HIV-1 ANTIBODY 2.2C
Descriptor:FAB 2.2C LIGHT CHAIN, FAB 2.2C HEAVY CHAIN, SULFATE ION, ...
Authors:McLellan, J.S., Acharya, P., Huang, C.-C., Robinson, J., Kwong, P.D.
Deposit date:2014-08-19
Release date:2014-09-10
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (2.199 Å)
Cite:Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection.
J.Virol., 88, 2014
3TCL
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CRYSTAL STRUCTURE OF HIV-1 NEUTRALIZING ANTIBODY CH04
Descriptor:CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE
Authors:Louder, R.K., McLellan, J.S., Pancera, M., Yang, Y., Zhang, B., Bonsignori, M., Kwong, P.D.
Deposit date:2011-08-09
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (1.906 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U46
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CH04H/CH02L P212121
Descriptor:CH04 Heavy chain Fab, CH02 Light chain Fab
Authors:Louder, R., Pancera, M., McLellan, J.S., Kwong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
3U4B
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CH04H/CH02L FAB P4
Descriptor:CH04 Heavy chain, CH02 Light chain
Authors:Pancera, M., Louder, R., Mclellan, J.S., KWong, P.D.
Deposit date:2011-10-07
Release date:2011-11-30
Last modified:2011-12-21
Method:X-RAY DIFFRACTION (2.893 Å)
Cite:Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.
Nature, 480, 2011
4HPO
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CRYSTAL STRUCTURE OF RV144-ELICITED ANTIBODY CH58 IN COMPLEX WITH V2 PEPTIDE
Descriptor:CH58 Fab heavy chain, CH58 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S., Gorman, J., Haynes, B.F., Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.694 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HPY
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CRYSTAL STRUCTURE OF RV144-ELICITED ANTIBODY CH59 IN COMPLEX WITH V2 PEPTIDE
Descriptor:CH59 Fab heavy chain, CH59 Fab light chain, Envelope glycoprotein gp160, ...
Authors:McLellan, J.S., Gorman, J., Haynes, B.F., Kwong, P.D.
Deposit date:2012-10-24
Release date:2013-02-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4HQQ
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CRYSTAL STRUCTURE OF RV144-ELICITED ANTIBODY CH58
Descriptor:CH58 Fab heavy chain, CH58 Fab light chain
Authors:McLellan, J.S., Haynes, B.F., Kwong, P.D.
Deposit date:2012-10-25
Release date:2013-02-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2.
Immunity, 38, 2013
4MMR
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT CAV1 AT PH 9.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain
Authors:Stewart-Jones, G.B.E., McLellan, J.S., Joyce, M.G., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013
4MMT
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CRYSTAL STRUCTURE OF PREFUSION-STABILIZED RSV F VARIANT DS-CAV1 AT PH 9.5
Descriptor:Fusion glycoprotein F2, Fusion glycoprotein F1 fused with Fibritin trimerization domain
Authors:Joyce, M.G., Mclellan, J.S., Stewart-Jones, G.B.E., Sastry, M., Yang, Y., Graham, B.S., Kwong, P.D.
Deposit date:2013-09-09
Release date:2013-11-20
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus.
Science, 342, 2013