Author results

2FM8
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CRYSTAL STRUCTURE OF THE SALMONELLA SECRETION CHAPERONE INVB IN COMPLEX WITH SIPA
Descriptor:Surface presentation of antigens protein spaK, Cell invasion protein sipA
Authors:Lilic, M., Vujanac, M., Stebbins, C.E.
Deposit date:2006-01-08
Release date:2006-03-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A common structural motif in the binding of virulence factors to bacterial secretion chaperones.
Mol.Cell, 21, 2006
2FM9
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STRUCTURE OF SALMONELLA SIPA RESIDUES 48-264
Descriptor:Cell invasion protein sipA
Authors:Lilic, M., Vujanac, M., Stebbins, C.E.
Deposit date:2006-01-08
Release date:2006-03-21
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:A common structural motif in the binding of virulence factors to bacterial secretion chaperones.
Mol.Cell, 21, 2006
1Q5Z
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CRYSTAL STRUCTURE OF THE C-TERMINAL ACTIN BINDING DOMAIN OF SALMONELLA INVASION PROTEIN A (SIPA)
Descriptor:SipA
Authors:Stebbins, C.E., Lilic, M., Galkin, V.E., Orlova, A., VanLoock, M.S., Egelman, E.H.
Deposit date:2003-08-11
Release date:2003-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Salmonella SipA polymerizes actin by stapling filaments with nonglobular protein arms.
Science, 301, 2003
3LW9
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STRUCTURE OF A CYTOPLASMIC DOMAIN OF SALMONELLA INVA
Descriptor:Invasion protein invA
Authors:Stebbins, C.E., Lilic, M., Quezada, C.M.
Deposit date:2010-02-23
Release date:2010-05-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A conserved domain in type III secretion links the cytoplasmic domain of InvA to elements of the basal body.
Acta Crystallogr.,Sect.D, 66, 2010
6CCE
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CRYSTAL STRUCTURE OF A MYCOBACTERIUM SMEGMATIS RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH INHIBITOR KANGLEMYCIN A
Descriptor:RNA polymerase-binding protein RbpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M., Darst, S.A., Campbell, E.A.
Deposit date:2018-02-07
Release date:2018-08-15
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
6CCV
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CRYSTAL STRUCTURE OF A MYCOBACTERIUM SMEGMATIS RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH INHIBITOR RIFAMPICIN
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lilic, M., Darst, S.A., Campbell, E.A.
Deposit date:2018-02-07
Release date:2018-08-15
Last modified:2019-05-15
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
6DCF
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CRYSTAL STRUCTURE OF A MYCOBACTERIUM SMEGMATIS TRANSCRIPTION INITIATION COMPLEX WITH RIFAMPICIN-RESISTANT RNA POLYMERASE AND BOUND TO KANGLEMYCIN A
Descriptor:RNA polymerase-binding protein RbpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M., Darst, S.A., Campbell, E.A.
Deposit date:2018-05-06
Release date:2018-09-05
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
6C04
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MTB RNAP HOLO/RBPA/DOUBLE FORK DNA -CLOSED CLAMP
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Darst, S.A., Campbell, E.A., Boyaci Selcuk, H., Chen, J., Lilic, M.
Deposit date:2017-12-27
Release date:2018-03-28
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
6C05
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MYCOBACTERIUM TUBERCULOSIS RNAP HOLO/RBPA IN RELAXED STATE
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Darst, S.A., Campbell, E.A., Boyaci Selcuk, H., Chen, J., Lilic, M.
Deposit date:2017-12-27
Release date:2018-03-28
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
6C06
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MYCOBACTERIUM TUBERCULOSIS RNAP HOLO/RBPA/FIDAXOMICIN
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Darst, S.A., Campbell, E.A., Boyaci Selcuk, H., Chen, J., Lilic, M.
Deposit date:2017-12-27
Release date:2018-03-28
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
5VI5
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STRUCTURE OF MYCOBACTERIUM SMEGMATIS TRANSCRIPTION INITIATION COMPLEX WITH A FULL TRANSCRIPTION BUBBLE
Descriptor:DNA (49-MER), DNA (44-MER), RNA (5'-R(*UP*CP*GP*A)-3'), ...
Authors:Darst, S.A., Campbell, E.A., Lilic, M.
Deposit date:2017-04-14
Release date:2017-07-26
Method:X-RAY DIFFRACTION (3.196 Å)
Cite:Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.
Nat Commun, 8, 2017
6BZO
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MTB RNAP HOLO/RBPA/FIDAXOMICIN/UPSTREAM FORK DNA
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Darst, S.A., Campbell, E.A., Boyaci Selcuk, H., Chen, J.
Deposit date:2017-12-25
Release date:2018-03-28
Last modified:2019-04-24
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Fidaxomicin jamsMycobacterium tuberculosisRNA polymerase motions needed for initiation via RbpA contacts.
Elife, 7, 2018
4YX1
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SPAO(SPOA2)
Descriptor:Surface presentation of antigens protein SpaO, CALCIUM ION
Authors:Notti, R.Q., Stebbins, C.E.
Deposit date:2015-03-21
Release date:2015-06-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4YX5
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SPAO(SPOA1,2)
Descriptor:Surface presentation of antigens protein SpaO, CHLORIDE ION
Authors:Notti, R.Q., Stebbins, C.E.
Deposit date:2015-03-22
Release date:2015-06-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.9001 Å)
Cite:A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4YX7
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COMPLEX OF SPAO(SPOA1,2) AND ORGB(APAR)::T4LYSOZYME FUSION PROTEIN
Descriptor:Surface presentation of antigens protein SpaO, Oxygen-regulated invasion protein OrgB,Endolysin
Authors:Notti, R.Q., Stebbins, C.E.
Deposit date:2015-03-22
Release date:2015-06-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.0007 Å)
Cite:A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4YXA
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COMPLEX OF SPAO(SPOA1,2 SEMET) AND ORGB(APAR)::T4LYSOZYME FUSION PROTEIN
Descriptor:Surface presentation of antigens protein SpaO, Oxygen-regulated invasion protein OrgB,Endolysin
Authors:Notti, R.Q., Stebbins, C.E.
Deposit date:2015-03-22
Release date:2015-06-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4YXB
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FLIM(SPOA)::FLIN FUSION PROTEIN
Descriptor:Flagellar motor switch protein FliM,Flagellar motor switch protein FliN, FliM::FliN fragment, Ambiguous peptide density, ...
Authors:Notti, R.Q., Stebbins, C.E.
Deposit date:2015-03-22
Release date:2015-06-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
4YXC
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COMPLEX OF FLIM(SPOA)::FLIN FUSION PROTEIN AND FLIH(APAR)::T4LYSOZYME FUSION PROTEIN
Descriptor:Flagellar assembly protein H,Endolysin, Flagellar motor switch protein FliM,Flagellar motor switch protein FliN
Authors:Notti, R.Q., Stebbins, C.E.
Deposit date:2015-03-23
Release date:2015-06-03
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A common assembly module in injectisome and flagellar type III secretion sorting platforms.
Nat Commun, 6, 2015
5VI8
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STRUCTURE OF A MYCOBACTERIUM SMEGMATIS TRANSCRIPTION INITIATION COMPLEX WITH AN UPSTREAM-FORK PROMOTER FRAGMENT
Descriptor:RNA polymerase-binding protein RbpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Hubin, E.A., Campbell, E.A., Darst, S.A.
Deposit date:2017-04-14
Release date:2017-04-26
Last modified:2019-01-30
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.
Nat Commun, 8, 2017
6ELC
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CRYSTAL STRUCTURE OF O-LINKED GLYCOSYLATED VSG3
Descriptor:Variant surface glycoprotein, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Stebbins, C.E.
Deposit date:2017-09-28
Release date:2018-07-11
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:African trypanosomes evade immune clearance by O-glycosylation of the VSG surface coat.
Nat Microbiol, 3, 2018