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4BK4
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CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN
Descriptor:EPHRIN TYPE-A RECEPTOR 4
Authors:Seiradake, E., Schaupp, A., del Toro Ruiz, D., Kaufmann, R., Mitakidis, N., Harlos, K., Aricescu, A.R., Klein, R., Jones, E.Y.
Deposit date:2013-04-22
Release date:2013-07-03
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BK5
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CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN IN COMPLEX WITH HUMAN EPHRIN A5 (AMINE-METHYLATED SAMPLE)
Descriptor:EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5
Authors:Seiradake, E., Schaupp, A., del Toro Ruiz, D., Kaufmann, R., Mitakidis, N., Harlos, K., Aricescu, A.R., Klein, R., Jones, E.Y.
Deposit date:2013-04-22
Release date:2013-07-03
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BKA
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CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN IN COMPLEX WITH HUMAN EPHRIN A5
Descriptor:EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5
Authors:Seiradake, E., Schaupp, A., del Toro Ruiz, D., Kaufmann, R., Mitakidis, N., Harlos, K., Aricescu, A.R., Klein, R., Jones, E.Y.
Deposit date:2013-04-23
Release date:2013-07-03
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (5.3 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BKF
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CRYSTAL STRUCTURE OF THE HUMAN EPHA4 ECTODOMAIN IN COMPLEX WITH HUMAN EPHRINB3
Descriptor:EPHRIN TYPE-A RECEPTOR 4, EPHRIN-B3
Authors:Seiradake, E., Schaupp, A., del Toro Ruiz, D., Kaufmann, R., Mitakidis, N., Harlos, K., Aricescu, A.R., Klein, R., Jones, E.Y.
Deposit date:2013-04-24
Release date:2013-07-03
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (4.65 Å)
Cite:Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4V2A
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HUMAN UNC5A ECTODOMAIN
Descriptor:NETRIN RECEPTOR UNC5A, N-ACETYL-D-GLUCOSAMINE
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2B
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RAT UNC5D IG DOMAIN 1
Descriptor:PROTEIN UNC5D
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2C
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MOUSE FLRT2 LRR DOMAIN IN COMPLEX WITH RAT UNC5D IG1 DOMAIN
Descriptor:FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2, PROTEIN UNC5D
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (4 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2D
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FLRT2 LRR DOMAIN
Descriptor:FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-07-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2E
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FLRT3 LRR DOMAIN
Descriptor:FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 3
Authors:Seiradake, E., del Toro, D., Nagel, D., Cop, F., Haertl, R., Ruff, T., Seyit-Bremer, G., Harlos, K., Border, E.C., Acker-Palmer, A., Jones, E.Y., Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2015-08-12
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development.
Neuron, 84, 2014
5AFB
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CRYSTAL STRUCTURE OF THE LATROPHILIN3 LECTIN AND OLFACTOMEDIN DOMAINS
Descriptor:LATROPHILIN-3, N-ACETYL-D-GLUCOSAMINE, SODIUM ION, ...
Authors:Jackson, V.A., del Toro, D., Carrasquero, M., Roversi, P., Harlos, K., Klein, R., Seiradake, E.
Deposit date:2015-01-21
Release date:2015-03-18
Last modified:2016-03-09
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural Basis of Latrophilin-Flrt Interaction.
Structure, 23, 2015
5FTT
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OCTAMERIC COMPLEX OF LATROPHILIN 3 (LEC, OLF) , UNC5D (IG, IG2, TSP1) AND FLRT2 (LRR)
Descriptor:NETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3, ...
Authors:Jackson, V.A., Mehmood, S., Chavent, M., Roversi, P., Carrasquero, M., del Toro, D., Seyit-Bremer, G., Ranaivoson, F.M., Comoletti, D., Sansom, M.S.P., Robinson, C.V., Klein, R., Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
5FTU
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TETRAMERIC COMPLEX OF LATROPHILIN 3, UNC5D AND FLRT2
Descriptor:NETRIN RECEPTOR UNC5D, LEUCINE-RICH REPEAT TRANSMEMBRANE PROTEIN FLRT2, ADHESION G PROTEIN-COUPLED RECEPTOR L3, ...
Authors:Jackson, V.A., Mehmood, S., Chavent, M., Roversi, P., Carrasquero, M., del Toro, D., Seyit-Bremer, G., Ranaivoson, F.M., Comoletti, D., Sansom, M.S.P., Robinson, C.V., Klein, R., Seiradake, E.
Deposit date:2016-01-15
Release date:2016-05-04
Last modified:2016-05-11
Method:X-RAY DIFFRACTION (6.01 Å)
Cite:Super-Complexes of Adhesion Gpcrs and Neural Guidance Receptors
Nat.Commun., 7, 2016
2XWH
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HCV-J6 NS5B POLYMERASE STRUCTURE AT 1.8 ANGSTROM
Descriptor:RNA DEPENDENT RNA POLYMERASE, POLYETHYLENE GLYCOL (N=34), DI(HYDROXYETHYL)ETHER
Authors:Scrima, N., Bressanelli, S.
Deposit date:2010-11-03
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes.
J.Virol., 85, 2011
2XXD
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HCV-JFH1 NS5B POLYMERASE STRUCTURE AT 1.9 ANGSTROM
Descriptor:RNA-DIRECTED RNA POLYMERASE, PHOSPHATE ION
Authors:Caillet-Saguy, C., Bressanelli, S.
Deposit date:2010-11-10
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.881 Å)
Cite:A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes.
J.Virol., 85, 2011
2XYM
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HCV-JFH1 NS5B T385A MUTANT
Descriptor:RNA-DIRECTED RNA POLYMERASE, PHOSPHATE ION
Authors:Simister, P.C., Caillet-Saguy, C., Bressanelli, S.
Deposit date:2010-11-18
Release date:2011-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.774 Å)
Cite:A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes.
J.Virol., 85, 2011
2NA4
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CURLI SECRETION SPECIFICITY FACTOR CSGE W48A/F79A MUTANT
Descriptor:Curli production assembly/transport component CsgE
Authors:Shu, Q., Krezel, A.M., Frieden, C.
Deposit date:2015-12-21
Release date:2016-06-15
Last modified:2016-08-31
Method:SOLUTION NMR
Cite:Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation.
Proc.Natl.Acad.Sci.USA, 113, 2016
3I5K
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CRYSTAL STRUCTURE OF THE NS5B POLYMERASE FROM HEPATITIS C VIRUS (HCV) STRAIN JFH1
Descriptor:RNA-directed RNA polymerase, PHOSPHATE ION
Authors:Simister, P.C., Schmitt, M., Lohmann, V., Bressanelli, S.
Deposit date:2009-07-05
Release date:2009-09-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of hepatitis C virus strain JFH1 polymerase
J.Virol., 83, 2009
5F2F
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CRYSTAL STRUCTURE OF PARA-BIPHENYL-2-METHYL-3', 5' DI-METHYL AMIDE MANNOSIDE BOUND TO FIMH LECTIN DOMAIN
Descriptor:Protein FimH, 5-[4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3-methyl-phenyl]-~{N}1,~{N}3-dimethyl-benzene-1,3-dicarboxamide, GLYCEROL
Authors:Kalas, V., Hultgren, S.J.
Deposit date:2015-12-01
Release date:2016-05-04
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.665 Å)
Cite:Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI.
Chemmedchem, 11, 2016
6B0B
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CRYSTAL STRUCTURE OF HUMAN APOBEC3H
Descriptor:APOBEC3H, RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3'), RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
Authors:Shaban, N.M., Shi, K., Banerjee, S., Harris, R.S., Aihara, H.
Deposit date:2017-09-14
Release date:2017-10-25
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.280062 Å)
Cite:The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.
Mol. Cell, 69, 2018
6BBO
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CRYSTAL STRUCTURE OF HUMAN APOBEC3H/RNA COMPLEX
Descriptor:APOBEC3H, RNA (5'-R(*UP*AP*AP*AP*AP*AP*AP*A)-3'), RNA (5'-R(*UP*UP*UP*UP*UP*UP*UP*U)-3'), ...
Authors:Shaban, N.M., Shi, K., Banerjee, S., Harris, R.S., Aihara, H.
Deposit date:2017-10-19
Release date:2018-01-10
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (3.428 Å)
Cite:The Antiviral and Cancer Genomic DNA Deaminase APOBEC3H Is Regulated by an RNA-Mediated Dimerization Mechanism.
Mol. Cell, 69, 2018