6MAQ

F9 Pilus Adhesin FmlH Lectin Domain from E. coli UTI89 in Complex with Galactoside 2'-{[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-nitro-[1,1'-biphenyl]-3-carboxylic acid

Summary for 6MAQ

Entry DOI	10.2210/pdb6maq/pdb
Descriptor	Fimbrial adhesin FmlD, GLYCEROL, 2'-{[2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl]oxy}-5-nitro[1,1'-biphenyl]-3-carboxylic acid, ... (4 entities in total)
Functional Keywords	pilus, adhesin, galactose, lectin, sugar binding protein, sugar binding protein-inhibitor complex, sugar binding protein/inhibitor
Biological source	Escherichia coli UTI89
Total number of polymer chains	1
Total formula weight	19029.09
Authors	Klein, R.D.,Hultgren, S.J. (deposition date: 2018-08-28, release date: 2019-09-04, Last modification date: 2023-12-13)
Primary citation	Maddirala, A.R.,Klein, R.,Pinkner, J.S.,Kalas, V.,Hultgren, S.J.,Janetka, J.W. Biphenyl Gal and GalNAc FmlH Lectin Antagonists of Uropathogenic E. coli (UPEC): Optimization through Iterative Rational Drug Design. J.Med.Chem., 62:467-479, 2019 Cited by PubMed: 30540910 DOI: 10.1021/acs.jmedchem.8b01561 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.31 Å)

Structure validation