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2F9T
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STRUCTURE OF THE TYPE III COAA FROM PSEUDOMONAS AERUGINOSA
Descriptor:Pantothenate Kinase
Authors:Leonardi, R., Yun, M.K., Chohnan, S., White, S.W., Rock, C.O., Jackowski, S.
Deposit date:2005-12-06
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Prokaryotic Type II and Type III Pantothenate Kinases: The Same Monomer Fold Creates Dimers with Distinct Catalytic Properties.
Structure, 14, 2006
2F9W
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STRUCTURE OF THE TYPE III COAA FROM PSEUDOMONAS AERUGINOSA
Descriptor:Pantothenate Kinase, PANTOTHENOIC ACID, 1,2-ETHANEDIOL, ...
Authors:Leonardi, R., Yun, M.K., Chohnan, S., White, S.W., Rock, C.O., Jackowski, S.
Deposit date:2005-12-06
Release date:2006-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Prokaryotic Type II and Type III Pantothenate Kinases: The Same Monomer Fold Creates Dimers with Distinct Catalytic Properties.
Structure, 14, 2006
1ESM
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STRUCTURAL BASIS FOR THE FEEDBACK REGULATION OF ESCHERICHIA COLI PANTOTHENATE KINASE BY COENZYME A
Descriptor:PANTOTHENATE KINASE, COENZYME A
Authors:Yun, M., Park, C.G., Kim, J.Y., Rock, C.O., Jackowski, S., Park, H.W.
Deposit date:2000-04-10
Release date:2000-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A.
J.Biol.Chem., 275, 2000
1ESN
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STRUCTURAL BASIS FOR THE FEEDBACK REGULATION OF ESCHERICHIA COLI PANTOTHENATE KINASE BY COENZYME A
Descriptor:PANTOTHENATE KINASE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Yun, M., Park, C.G., Kim, J.Y., Rock, C.O., Jackowski, S., Park, H.W.
Deposit date:2000-04-10
Release date:2000-11-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A.
J.Biol.Chem., 275, 2000
1SQ5
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CRYSTAL STRUCTURE OF E. COLI PANTOTHENATE KINASE
Descriptor:Pantothenate kinase, PANTOTHENOIC ACID, ADENOSINE-5'-DIPHOSPHATE
Authors:Ivey, R.A., Zhang, Y.-M., Virga, K.G., Hevener, K., Lee, R.E., Rock, C.O., Jackowski, S., Park, H.-W.
Deposit date:2004-03-17
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites.
J.Biol.Chem., 279, 2004
2EWS
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CRYSTAL STRUCTURE OF S.AUREUS PANTOTHENATE KINASE
Descriptor:Pantothenate kinase, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Hong, B.S., Park, H.W., Structural Genomics Consortium (SGC)
Deposit date:2005-11-06
Release date:2006-09-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Prokaryotic Type II and Type III Pantothenate Kinases: The Same Monomer Fold Creates Dimers with Distinct Catalytic Properties.
Structure, 14, 2006
1JYK
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CATALYTIC MECHANISM OF CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE FROM STREPTOCOCCUS PNEUMONIAE (LICC)
Descriptor:CTP:phosphocholine Cytidylyltransferase
Authors:Kwak, B.-Y., Yun, M., Park, H.-w.
Deposit date:2001-09-12
Release date:2002-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure and mechanism of CTP:phosphocholine cytidylyltransferase (LicC) from Streptococcus pneumoniae.
J.Biol.Chem., 277, 2002
1JYL
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CATALYTIC MECHANISM OF CTP:PHOSPHOCHOLINE CYTIDYLYLTRANSFERASE FROM STREPTOCOCCUS PNEUMONIAE (LICC)
Descriptor:CTP:phosphocholine Cytidylyltransferase, MAGNESIUM ION, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM
Authors:Kwak, B.-Y., Yun, M., Park, H.-w.
Deposit date:2001-09-12
Release date:2002-02-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and mechanism of CTP:phosphocholine cytidylyltransferase (LicC) from Streptococcus pneumoniae.
J.Biol.Chem., 277, 2002
2H3G
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STRUCTURE OF THE TYPE III PANTOTHENATE KINASE (COAX) FROM BACILLUS ANTHRACIS
Descriptor:BIOSYNTHETIC PROTEIN, 1,2-ETHANEDIOL
Authors:Nicely, N.I.
Deposit date:2006-05-22
Release date:2007-03-20
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Type III Pantothenate Kinase from Bacillus anthracis at 2.0 A Resolution: Implications for Coenzyme A-Dependent Redox Biology.
Biochemistry, 46, 2007
2I7N
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CRYSTAL STRUCTURE OF HUMAN PANK1 ALPHA: THE CATALYTIC CORE DOMAIN IN COMPLEX WITH ACCOA
Descriptor:Pantothenate kinase 1, ACETYL COENZYME *A
Authors:Hong, B.S., Wang, L., Tempel, W., Loppnau, P., Allali-Hassani, A., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H.W.
Deposit date:2006-08-31
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.
J.Biol.Chem., 282, 2007
2I7P
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CRYSTAL STRUCTURE OF HUMAN PANK3 IN COMPLEX WITH ACCOA
Descriptor:Pantothenate kinase 3, ACETYL COENZYME *A
Authors:Hong, B.S., Wang, L., Shen, L., Tempel, W., Loppnau, P., Finerty, P., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Park, H.W., Structural Genomics Consortium (SGC)
Deposit date:2006-08-31
Release date:2006-12-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structures of human pantothenate kinases. Insights into allosteric regulation and mutations linked to a neurodegeneration disorder.
J.Biol.Chem., 282, 2007
3MK6
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SUBSTRATE AND INHIBITOR BINDING TO PANK
Descriptor:Pantothenate kinase 3, ACETYL COENZYME *A, GLYCEROL
Authors:Yun, M.-K., White, S.W.
Deposit date:2010-04-14
Release date:2010-09-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Modulation of Pantothenate Kinase 3 Activity by Small Molecules that Interact with the Substrate/Allosteric Regulatory Domain.
Chem.Biol., 17, 2010
5KPR
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PANK3-AMPPNP-PANTOTHENATE COMPLEX
Descriptor:Pantothenate kinase 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:White, S.W., Yun, M.
Deposit date:2016-07-05
Release date:2016-08-31
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (1.827 Å)
Cite:Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
5KPT
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PANK3-AMPPNP COMPLEX
Descriptor:Pantothenate kinase 3, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:White, S.W., Yun, M.
Deposit date:2016-07-05
Release date:2016-08-31
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
5KPZ
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PANK3-ADP-PHOSPHOPANTOTHENATE COMPLEX
Descriptor:Pantothenate kinase 3, N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanine, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:White, S.W., Yun, M.
Deposit date:2016-07-05
Release date:2016-08-31
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
5KQ8
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PANK3-AMPPN COMPLEX
Descriptor:Pantothenate kinase 3, AMP PHOSPHORAMIDATE, MAGNESIUM ION, ...
Authors:White, S.W., Yun, M.
Deposit date:2016-07-05
Release date:2016-08-31
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
5KQD
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PANK3:PALMITOYL-COA COMPLEX
Descriptor:Pantothenate kinase 3, Palmitoyl-CoA, SULFATE ION
Authors:White, S.W., Yun, M.
Deposit date:2016-07-06
Release date:2016-08-31
Last modified:2016-10-26
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Allosteric Regulation of Mammalian Pantothenate Kinase.
J.Biol.Chem., 291, 2016
6B3V
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PANK3 COMPLEX WITH COMPOUND PZ-2891
Descriptor:Pantothenate kinase 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ...
Authors:White, S.W., Yun, M.
Deposit date:2017-09-25
Release date:2018-08-29
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.601 Å)
Cite:A therapeutic approach to pantothenate kinase associated neurodegeneration.
Nat Commun, 9, 2018
1EBL
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THE 1.8 A CRYSTAL STRUCTURE AND ACTIVE SITE ARCHITECTURE OF BETA-KETOACYL-[ACYL CARRIER PROTEIN] SYNTHASE III (FABH) FROM ESCHERICHIA COLI
Descriptor:BETA-KETOACYL-ACP SYNTHASE III, COENZYME A
Authors:Davies, C., Heath, R.J., White, S.W., Rock, C.O.
Deposit date:2000-01-24
Release date:2000-02-11
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli.
Structure Fold.Des., 8, 2000